Abstract:
OBJECTIVES:To use two population-based samples of prostate cancer-free men to develop and validate a novel multivariable equation for estimating prostate volume (PV). Previous investigators have demonstrated the ability to use serum prostate-specific antigen (PSA) levels to estimate PV in men without prostate cancer; however, the ability of additional clinical variables to further enhance PV estimation in these men remains unclear. METHODS:We applied linear regression modeling to data from an 80% random sample (n = 366) of the baseline cohort from the Olmsted County Study of Urinary Symptoms and Health Status among Men (OCS) to develop an equation for estimating PV in men without prostate cancer. We then evaluated the predictive ability of this equation by comparing estimated and measured PV values in 3 additional validation sets of men. RESULTS:The final linear regression model included PSA, age, and weight as independent predictors of PV. For prediction in baseline OCS men, the multiple correlation coefficients increased from 0.62(PSAalone) to 0.71(fullmodel). In addition, the area under the curve estimates from the receiver operating characteristic curves increased from 0.79(PSAalone) to 0.85(fullmodel) for predicting PV >30 mL. CONCLUSIONS:Our data suggest that PV can be estimated with easily obtained clinical variables. Moreover, we demonstrate that age and weight can be added to PSA level to achieve greater accuracy in predicting PV. This methodology may prove useful for estimating PV in men in settings where costs and practicality preclude the use of imaging techniques.
journal_name
Urologyjournal_title
Urologyauthors
Jacobson DJ,St Sauver JL,Parker AS,McGree ME,Sarma AV,Girman CJ,Lieber MM,Jacobsen SJdoi
10.1016/j.urology.2010.05.044subject
Has Abstractpub_date
2011-02-01 00:00:00pages
422-6issue
2eissn
0090-4295issn
1527-9995pii
S0090-4295(10)00783-1journal_volume
77pub_type
杂志文章相关文献
UROLOGY文献大全abstract:OBJECTIVES:To assess the effects of saw palmetto on voiding symptoms and urodynamic parameters in men with lower urinary tract symptoms (LUTS) presumed secondary to benign prostatic hyperplasia (BPH). METHODS:Fifty men with previously untreated LUTS and a minimum International Prostate Symptom Score (IPSS) of 10 or gr...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(98)00143-5
更新日期:1998-06-01 00:00:00
abstract::A total of 152 patients had cytology and cystoscopy performed for either initial or recurrent bladder tumors and postoperative control examinations. Positive cytology was found in 97 per cent of patients with pathologically proved bladder tumors. However, 23 per cent of the patients with negative cytology had positive...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(79)90024-4
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVES:Demographic information on patients presenting for the diagnosis and treatment of male factor infertility has been limited in the past by the paucity of subspecialty trained providers and concentrated sequential patient information. Previously reported studies looking at the characteristics of patients being...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(01)01400-5
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVES:Prostate cancer incidence varies significantly among different ethnic groups. However, little is known about the survival outcome among groups. We sought to compare the survival outcome in patients with metastatic prostate cancer among different ethnic groups and to identify independent prognostic factors af...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2008.01.026
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:To investigate the clinical utility of the subforms of free prostate-specific antigen (PSA), namely proPSA and "benign" PSA (BPSA), to improve cancer detection when the percent free PSA level is less than 15%. Percent free PSA, while maintaining sensitivity, has greatly improved the specificity of PSA for th...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2004.06.033
更新日期:2004-12-01 00:00:00
abstract::A Cowper's Duct syringocele is a rare diagnosis and currently there exists no clinical guidelines for evaluation and management. This clinical challenge illustrates the case presentation, evaluation, diagnosis, and treatment options for of a newly diagnosed Cowper's Duct syringocele. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.10.032
更新日期:2020-11-04 00:00:00
abstract::The clinical necessities of replacing all or part of the diseased or destroyed ureter have plagued surgeons for many years. In the past seventy years more than 100 surgical techniques have been described for ureteral replacement. Methods of replacement have fallen into four categories; nonbiologic substitutes, pedicle...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/0090-4295(75)90001-1
更新日期:1975-02-01 00:00:00
abstract:OBJECTIVES:To examine clinical and pathologic features and postoperative survival outcomes of men with prostate cancer detected by digital rectal examination (DRE) alone, elevated prostate-specific antigen (PSA) level alone, or abnormalities in both. METHODS:From 1989 to 2001, approximately 36,000 men participated in ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.07.019
更新日期:2007-12-01 00:00:00
abstract::A classification of the various ganglionic stimulants and blockers is presented, and their pharmacologic effects on the urinary bladder and urethra are discussed. Ganglionic stimulating drugs are of considerable interest in investigational work but are not presently used therapeutically. Ganglionic blockers include he...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/0090-4295(78)90252-2
更新日期:1978-04-01 00:00:00
abstract::Renal angiomyolipoma has traditionally been considered a benign tumor. Recently, a variety of epithelioid angiomyolipomas with malignant potential have been described. We report an adrenal recurrence in a patient who had a cellular angiomyolipoma removed 4 years earlier. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(02)02584-0
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:Patients with posterior urethral valves (PUV) are at significant risk for progression to end-stage renal disease, despite early correction of the obstruction. Experimental models of urinary obstruction demonstrate increased renal expression of the profibrotic inflammatory mediator, transforming growth factor...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(00)00591-4
更新日期:2000-08-01 00:00:00
abstract::We report a case of invasive cytomegalovirus (CMV) infection in the native ureter of a patient 7 years after liver-kidney transplantation. Previous reports of CMV ureteritis in transplant patients have involved only the allograft ureter, usually within 3 months of transplantation. The common characteristics of these p...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00084-9
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:To determine if partial nephrectomy (PN) confers a renal functional benefit compared to radical nephrectomy (RN) for clinical T2 renal masses (T2RM) when adjusting for tumor complexity characterized by the RENAL nephrometry score. METHODS:A 2-center study of 202 patients with T2RM undergoing RN (122) or PN (...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2015.02.067
更新日期:2015-08-01 00:00:00
abstract::A great variety of self-inflicted foreign bodies have been removed from the lower urinary tract and male external genitalia. These foreign bodies were inserted or applied for autoerotic, psychiatric, therapeutic, or no definite reasons by the patient. Most patients were too ashamed to admit they had inserted or applie...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(85)90245-6
更新日期:1985-07-01 00:00:00
abstract:OBJECTIVES:In this pilot study, the effect of dosing schedule on the efficacy and safety of the long-acting alpha 1-adrenergic blocker doxazosin (DOX) was evaluated in 48 consecutive, normotensive men (mean age, 61.2 years) with symptoms of prostatism. METHODS:In this titration to fixed dose study, patients were rando...
journal_title:Urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0090-4295(94)80092-8
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:To determine the effect irrigation fluid temperature has on core body temperature changes in patients undergoing transurethral resection of the prostate (TURP). METHODS:Fifty-six male patients (mean age 71.2 +/- 8.2 years) scheduled for TURP were enrolled in the study. Patients were randomized to one of two...
journal_title:Urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0090-4295(01)00993-1
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To report our experience with salvage high-intensity focused ultrasound (HIFU) in patients with local failure after brachytherapy for prostate cancer. PATIENTS AND METHODS:Whole-gland HIFU was administered to prospectively recruited patients with local histologic failure after brachytherapy at 2 institutions...
journal_title:Urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.urology.2014.06.054
更新日期:2014-11-01 00:00:00
abstract::We present an eighty-three-year-old man with an exophytic lesion in the prostatic cavity, diagnosed three years after transurethral resection of the prostate, and extending into the bladder. Histopathologically, the tumor was recognized as a papillary ductal adenocarcinoma (primary duct type) with endometrioid feature...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/0090-4295(94)90202-x
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVES:To study the role of urethral sonography and color Doppler imaging in the evaluation of patients with urethral strictures and associated abnormalities. METHODS:We reviewed our experience with 41 urethral sonographic studies in 35 patients and compared them to 33 retrograde urethrograms. For 6 recent cases, ...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(99)80391-4
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:To assess the hemodynamics of the cavernous arteries (CAs) and helicine arteries (HAs) using power Doppler imaging (PDI) in patients with erectile dysfunction (ED). METHODS:Forty-two patients with and without a definite vascular component of ED were examined by PDI. The hemodynamic variables of the CAs and ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(02)01764-8
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:To assess the correlations in males with spinal cord injury (SCI) between the neurologic status and type of detrusor-sphincter dyssynergia (DSD) observed during urodynamic examinations and to evaluate the change in the DSD pattern over time. METHODS:A total of 105 male patients with chronic SCI were neurolo...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2004.09.024
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVES:Androgen ablation with luteinizing hormone-releasing hormone (LHRH) agonists, orchiectomy, or oral estrogens has significant untoward sexual side effects. We evaluated a combination of finasteride and flutamide as potency-sparing androgen ablative therapy (AAT) for advanced adenocarcinoma of the prostate. In...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(97)00091-5
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVES:The presence of metastatic lesions is the only acceptable fact to confirm malignant pheochromocytoma. Patients with malignant pheochromocytomas, however, have a very poor survival rate. The aim of our study was to postulate predictive values for malignant pheochromocytomas. METHODS:We evaluated symptoms, di...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00612-8
更新日期:1999-04-01 00:00:00
abstract::Ninety-three cases of germinal testicular tumors with urinary gonadotropin (HCG) values, estimated by biologic or radioimmunoassay techniques, were reviewed. Preoperative values of HCG and subsequent postoperative values were related to response to treatment and prognosis. Twenty-five patients (26.9 per cent) comprise...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(75)90074-6
更新日期:1975-04-01 00:00:00
abstract::We report the case of a calcified angiomyolipoma of the kidney, fortuitously discovered on a computed tomography scan of the abdomen. Because of the presence of intratumoral calcification and macroscopic fat, renal cell carcinoma could not be ruled out by imaging. Biopsy of the mass was performed, and pathological stu...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.07.011
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To review the evidence suggesting a significant association between gout and erectile dysfunction (ED) and evaluate possible underlying pathways that may explain this relationship. METHODS:English medical literature was searched from January 1, 2010, to January 1, 2020, for randomized or quasi-randomized con...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2020.12.005
更新日期:2020-12-17 00:00:00
abstract::The surgical riks were analyzed in 305 patients with end stage renal failure who underwent bilateral nephrectomy through midabdominal approach in preparation for kidney transplantation. The over-all mortality rate was 3.6 per cent. Age was the most significant risk factor in the mortality. Patients less than fifty yea...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(78)90367-9
更新日期:1978-07-01 00:00:00
abstract:OBJECTIVES:Several studies have shown that 5-aminolevulinic acid (5-ALA)-induced fluorescence cystoscopy improves the detection of superficial bladder cancer. The results have suggested a reduced rate of recurrent tumors with the use of 5-ALA fluorescence before bladder tumor resection. We performed a prospective, rand...
journal_title:Urology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.urology.2006.12.023
更新日期:2007-04-01 00:00:00
abstract::A patient with bilateral cryptorchidism and gynecomastia due to Leydig cell tumor involving the left intra-abdominal testis is described. Raised serum estrogen, low serum testosterone, and ultrasonic demonstration of a tumor in the left testis allowed the diagnosis to be suspected preoperatively. The relevant literatu...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(93)90546-m
更新日期:1993-12-01 00:00:00
abstract::We devised an intracorporeal one-hand tie technique to ligate the renal pedicle during hand-assisted retroperitoneoscopic nephrectomy. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.09.035
更新日期:2007-11-01 00:00:00