Abstract：
BACKGROUND:Most patients with primary hyperparathyroidism undergo localization prior to operation with variable success. Therefore, in this study we investigated the safety of parathyroidectomy without imaging. METHODS:A prospective database of 2057 surgical patients with primary hyperparathyroidism from 2001 to 2019 was reviewed. Patients were categorized by use of preoperative imaging (ultrasound, sestamibi, CT scan), pathology, and cure. RESULTS:1879 (91%) patients underwent preoperative imaging. CT scan was the most sensitive study (92%), though specificity was only 64%. Patients with imaging were older, had higher pre- and postoperative calcium, more likely to undergo unilateral exploration and have an adenoma (p < 0.001-0.038). No differences were seen in nerve injury (<1%), postoperative hypocalcemia (<1%), or cure rate. CONCLUSIONS:While localization may lead to minimally-invasive operations, we observed no differences in postoperative complications or cure rates in the hands of an experienced surgeon. Therefore, preoperative parathyroid localization does not improve outcomes for hyperparathyroidism and can be ordered sparingly.
journal_name
Am J Surgjournal_title
American journal of surgeryauthors
Fazendin JM,Lindeman B,Chen Hdoi
10.1016/j.amjsurg.2020.04.029subject
Has Abstractpub_date
2020-09-01 00:00:00pages
533-535issue
3eissn
0002-9610issn
1879-1883pii
S0002-9610(20)30234-8journal_volume
220pub_type
杂志文章abstract：:A patient with the classic manifestations of the glucagonoma syndrome and hepatic metastases is presented. Clinical improvement occurred after removal of the primary tumor by distal pancreatectomy and splenectomy. No further antitumor therapy has been needed over a 15 month postoperative follow-up despite metastatic d...
journal_title：American journal of surgery
pub_type： 杂志文章
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更新日期：1980-03-01 00:00:00
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journal_title：American journal of surgery
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journal_title：American journal of surgery
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journal_title：American journal of surgery
pub_type： 杂志文章
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journal_title：American journal of surgery
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journal_title：American journal of surgery
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journal_title：American journal of surgery
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journal_title：American journal of surgery
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journal_title：American journal of surgery
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journal_title：American journal of surgery
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更新日期：1989-02-01 00:00:00
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journal_title：American journal of surgery
pub_type： 杂志文章
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更新日期：1977-08-01 00:00:00
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journal_title：American journal of surgery
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journal_title：American journal of surgery
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更新日期：1979-06-01 00:00:00
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doi：10.1016/j.amjsurg.2008.01.004
更新日期：2008-05-01 00:00:00
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journal_title：American journal of surgery
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更新日期：1995-08-01 00:00:00
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journal_title：American journal of surgery
pub_type： 杂志文章
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journal_title：American journal of surgery
pub_type： 杂志文章,随机对照试验
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更新日期：2006-10-01 00:00:00
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journal_title：American journal of surgery
pub_type： 评论,杂志文章
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更新日期：2008-07-01 00:00:00
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journal_title：American journal of surgery
pub_type： 杂志文章
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更新日期：1993-12-01 00:00:00
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journal_title：American journal of surgery
pub_type： 历史文章,杂志文章
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更新日期：1984-06-01 00:00:00
