Abstract：
:This is a commentary on Besser and colleagues' article "Associations between neighbourhood built environment and cognition vary by apolipoprotein E genotype: Multi-Ethnic Study on Atherosclerosis" published in Health & Place. Unlike previous studies, the authors found significant environment-cognition associations in apolipoprotein E (APOE) ε2 carriers and no significant associations in ε4 carriers. This commentary discusses the possible reasons for these findings and, in doing so, proposes an ecological model of cognitive health. The model highlights the importance of accounting for multiple environmental influences including the built and natural environment and air and noise pollution indicators. It also stresses the importance of studying the underlying biological mechanisms explaining differences in environment-cognition associations across APOE genotype categories.
journal_name
Health Placejournal_title
Health & placeauthors
Cerin Edoi
10.1016/j.healthplace.2019.102206subject
Has Abstractpub_date
2019-11-01 00:00:00pages
102206eissn
1353-8292issn
1873-2054pii
S1353-8292(19)31000-7journal_volume
60pub_type
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