Pulmonary venous invasion, determined by chest computed tomographic scan, as a potential early indicator of zygomycosis infection: a case series.

Abstract:

:Zygomycosis is a life-threatening fungal infection, and its successful treatment requires early diagnosis. To establish radiologic and clinical criteria for early diagnosis, we reviewed 3 post-mortem cases with zygomycosis secondary to hematological diseases. In all cases, an irregular dilatation of pulmonary veins on computed tomography suggested venous invasion by fungal hyphae, which was confirmed at autopsy. In addition, serum samples tested negative for the Aspergillus galactomannan antigen in all cases. These distinguishing radiologic and clinical features may contribute to an earlier diagnosis; more radical treatments, such as amphotericin-B or pulmonary resection; and a more successful outcome for patients with zygomycosis.

journal_name

J Thorac Imaging

authors

Kitagawa H,Watanabe K,Kage H,Inoh S,Goto A,Fukayama M,Nagase T,Ohishi N,Takai D

doi

10.1097/RTI.0b013e3182282d17

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

W97-9

issue

4

eissn

0883-5993

issn

1536-0237

journal_volume

27

pub_type

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