Abstract:
: Objectives: Malignant ureteral obstruction (MUO) is a devastating complication of cancer, and it is commonly treated by drainage via percutaneous nephrostomy (PCN). The objective of this study was to determine the efficacy, safety, and functional outcome of tandem ureteral stents (TUS) in the management of MUO. Materials and Methods: The medical records of all patients with MUO who underwent balloon dilation and TUS insertion in Sheba Medical Center between 2014 and 2018 were retrospectively analyzed. Safety was measured by intra- and postoperative complications, efficacy by time to event analysis, and failure by the requirement of PCN attributable to renal failure or infection. Independent risk predictors of TUS failure were determined by a multivariable Cox regression analysis. Results: A total of 103 procedures were performed on 81 patients during the study period. The median follow-up was 32 weeks (interquartile range [IQR] 24-67). Fifty-nine (72.9%) patients remained with TUS while 22 patients required PCNs. The median time to procedural failure was 4 months (IQR 2-8). Complications developed after 18 (22.2%) procedures. Two patients requested stent removal due to lower urinary tract symptoms. Independent predictors for TUS failure were metastasis (hazard ratio [HR] 3.03, 95% confidence interval [CI] 1.27, 7.23, p = 0.013) and prior PCN (HR 3.38, 95% CI 1.40, 8.13, p = 0.007). Conclusions: TUS is an efficient and safe management option for patients with MUO. It can alleviate renal failure without the need for an external PCN. Metastasis and prior PCN are associated with TUS failure.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Haifler M,Shvero A,Zilberman D,Ramon J,Winkler H,Margel D,Kleinmann Ndoi
10.1089/end.2019.0685subject
Has Abstractpub_date
2020-02-01 00:00:00pages
222-226issue
2eissn
0892-7790issn
1557-900Xjournal_volume
34pub_type
杂志文章abstract:OBJECTIVE:Hospitalization and general anesthesia to perform transurethral resection of bladder tumors (BTs) may not be necessary for small recurrent BTs. We developed a new outpatient procedure. PATIENTS AND METHODS:Patients with recurrent small tumors who had previously undergone transurethral resection of BTs for lo...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2009.0250
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:The impact of drainage type after percutaneous nephrolithotomy (PCNL) on the health-related quality of life (HRQoL) has been rarely studied. We conducted a prospective randomized study to evaluate the differences in HRQoL among patients who received different drainage types. METHODS:A total of 90 patients who ...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
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更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Biodegradable urethral stents have been used clinically for some years mainly in order to prevent postoperative urinary retention after minimally invasive thermotreatment of benign prostatic hyperplasia. We previously reported a 15-month-follow-up pilot study of a bioabsorbable self-expandable, s...
journal_title:Journal of endourology
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
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doi:10.1089/end.1999.13.299
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pub_type: 杂志文章
doi:10.1089/end.1994.8.131
更新日期:1994-04-01 00:00:00
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
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更新日期:2011-11-01 00:00:00
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277903322145521
更新日期:2003-06-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章,评审
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更新日期:2019-10-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2009-03-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/end.1999.13.141
更新日期:1999-04-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2008-04-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2010-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2008-06-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2008-07-01 00:00:00
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
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更新日期:2008-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2011-03-01 00:00:00
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:1997-12-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2009-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-10-01 00:00:00
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