Prognostic value of the preoperative prognostic nutritional index in oldest-old patients with colorectal cancer.

Abstract:

BACKGROUND:The prognostic nutritional index (PNI), which is calculated using serum albumin and the peripheral lymphocyte count, is a simple and useful score for predicting the prognosis in patients with various cancers. The correlation between the preoperative PNI and long-term outcomes is unclear in oldest-old patients with colorectal cancer. METHODS:A total of 84 consecutive patients ≥ 85 years old who underwent resection for primary colon adenocarcinoma at our institution between April 2008 and March 2017 were retrospectively reviewed. The cut-off value of the PNI for predicting the relapse-free survival (RFS) was 42.4 on a receiver operating characteristic curve analysis. The clinical characteristics and markers of systemic inflammation were then compared between patients with a low PNI (PNI < 42.4, n = 33) and a high PNI (PNI ≥ 42.4, n = 51). RESULTS:A low PNI was associated with systemic inflammation marker levels, including a low neutrophil-to-lymphocyte ratio (p = 0.048), a low platelet-to-lymphocyte ratio (p = 0.006), and a high lymphocyte-to-monocyte ratio (p < 0.001). The median follow-up period of this cohort was 34 months (1-151 months). The 5-year RFS, overall survival (OS), and cancer-specific survival were significantly worse in the low-PNI group than in the high-PNI group (p = 0.032, p = 0.004, p = 0.049, respectively). In the multivariate analysis, a low PNI was an independent predictor for both the RFS (HR 3.188, p = 0.041) and OS (HR 3.953, p = 0.027). CONCLUSIONS:A low-preoperative PNI was significantly associated with a poor prognosis in oldest-old colorectal cancer patients. Perioperative nutritional support may be important for prolonging the survival.

journal_name

Surg Today

journal_title

Surgery today

authors

Tominaga T,Nonaka T,Hisanaga M,Fukuda A,Tanoue Y,Yoshimoto T,Hidaka S,Sawai T,Nagayasu T

doi

10.1007/s00595-019-01910-w

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

449-459

issue

5

eissn

0941-1291

issn

1436-2813

pii

10.1007/s00595-019-01910-w

journal_volume

50

pub_type

杂志文章
  • Clinical manifestations of acute appendicitis in hemodialysis patients.

    abstract:PURPOSE:Acute appendicitis has been suggested to be more aggravated in hemodialysis (HD) patients in comparison to non-HD patients but only scanty evidence demonstrates the conditions. METHODS:A retrospective cohort study was done for HD and non-HD patients with a discharge diagnosis of acute appendicitis in a single ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0349-8

    authors: Wu HC,Yan MT,Lu KC,Chu P,Lin SH,Yu JC,Wu CC

    更新日期:2013-09-01 00:00:00

  • Revascularization to prevent postoperative bowel infarction after surgery for acute superior mesenteric artery thromboembolism.

    abstract:PURPOSE:Postoperative bowel infarction is a major contributing factor to the high mortality rate associated with acute thromboembolism of the superior mesenteric artery (SMA). This study was conducted to evaluate the prophylactic role of thrombectomy to prevent postoperative mesenteric infarction. METHODS:An autologou...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950200028

    authors: Sakaguchi S,Minowa K,Shibanushi T,Ichino M,Mitsuoka H,Unno N,Yamamoto N,Nakamura S

    更新日期:2002-01-01 00:00:00

  • Super-elderly patient-specific perioperative complications in breast cancer surgery.

    abstract:PURPOSE:Geriatric surgery poses specific challenges due to patient vulnerability in relation to aging. We analyzed perioperative challenges concerning super-elderly patients with breast cancer. METHODS:Between 2013 and 2018, 908 patients with breast cancer were treated surgically. Of these, two patient groups were com...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-01812-x

    authors: Ogawa Y,Ikeda K,Watanabe C,Kamei Y,Goto W,Shiraishi C,Tokunaga S,Tsuboguchi Y

    更新日期:2019-10-01 00:00:00

  • Adenocarcinoma in the jejunal pouch after proximal gastrectomy for early stage upper gastric cancer: report of a case.

    abstract::An 84-year-old male was admitted to a local clinic suffering from general fatigue with associated anemia, and therefore was referred to our hospital. His medical history included a proximal gastrectomy with the formation of a jejunal pouch as a reconstructive treatment for early upper gastric cancer at 78 years of age...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0125-9

    authors: Kurokawa T,Kanai M,Kaneko Y,Takahashi H,Motohara T

    更新日期:2012-06-01 00:00:00

  • Effects of resveratrol on incisional wound healing in rats.

    abstract:PURPOSE:The objective of this study was to investigate the effect of resveratrol on the healing process after midline laparotomy in rats. METHODS:The study was performed on adult female Wistar-Albino rats. The study group was orally administered 0.5 mg/kg resveratrol once a day for 7 days before the operation until 12...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0455-7

    authors: Yaman I,Derici H,Kara C,Kamer E,Diniz G,Ortac R,Sayin O

    更新日期:2013-12-01 00:00:00

  • Videothoracoscopic management of middle esophageal diverticulum with secondary bronchoesophageal fistula: report of a case.

    abstract::Middle esophageal diverticulum is rare, but can result in bronchoesophageal fistula. Previous reports have described open surgical techniques to treat esophageal diverticula, but few have evaluated the effectiveness of a videothoracoscopy approach. We report a case of middle esophageal diverticulum associated with bro...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3797-4

    authors: Braghetto I,Cardemil G,Schwartz E,Valladares H,Rencoret G,Estay R,Rodriguez-Navarro AJ

    更新日期:2008-01-01 00:00:00

  • Laparoscopic management of small bowel incarceration caused by a broad ligament defect: report of a case.

    abstract::We report the case of a 94-year-old woman who presented with signs of a small bowel obstruction many years after an appendectomy. Abdominal computed tomography (CT) scan showed discontinuity of the small bowel at a point next to the uterus. We made a provisional diagnosis of an internal hernia through a defect in the ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3397-0

    authors: Takayama S,Hirokawa T,Sakamoto M,Takahashi H,Yamamoto M,Sato M,Manabe T

    更新日期:2007-01-01 00:00:00

  • Epidural administration of droperidol suppresses cisplatin-induced emesis: preliminary findings.

    abstract::To evaluate the antiemetic effect of the epidural administration of droperidol on cisplatin-induced emesis, nine adult gastric cancer patients receiving intraoperative cisplatin chemotherapy were studied. After removal of the stomach, 0.05 mg/kg droperidol with 5 ml saline was injected into the epidural space through ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050114

    authors: Iwama H,Arai M

    更新日期:1998-01-01 00:00:00

  • Clinical evaluation of leukocyte filtration as an alternative anti-inflammatory strategy to aprotinin in high-risk patients undergoing coronary revascularization.

    abstract:PURPOSE:The use of aprotinin in cardiac surgery is associated with overriding safety concerns. Therefore, there is increased research on alternatives. This study investigated the relative benefits of strategic leukofiltration on polymer-coated extracorporeal circuits (ECC), aprotinin, and combined therapy in high-risk ...

    journal_title:Surgery today

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00595-011-0012-9

    authors: Farsak B,Gunaydin S,Yildiz U,Sari T,Zorlutuna Y

    更新日期:2012-04-01 00:00:00

  • Laparoscopic management of an obstructing granulocytic sarcoma of the jejunum causing intussusception in a nonleukemic patient: report of a case.

    abstract::Granulocytic sarcoma is an extramedullary tumor of immature myeloid cells which is often a forerunner to the development of acute myelogenous leukemia. Granulocytic sarcoma of the gastrointestinal tract frequently involves the small intestine and often presents with abdominal pain and obstruction. Our patient presente...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-007-3807-y

    authors: Palanivelu C,Rangarajan M,Senthilkumar R,Annapoorni S

    更新日期:2009-01-01 00:00:00

  • Peripheral edema after esophagectomy.

    abstract::Patients who have undergone major surgery such as esophagectomy may develop peripheral edema in the immediate postoperative period, the cause of which is not fully understood. The purpose of this study was therefore to determine the mechanism of this phenomenon. Finger edema was measured as a marker for peripheral ede...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02483601

    authors: Minamiya Y,Kitamura M,Saito R,Saito H,Matsumoto H,Abo S

    更新日期:1998-01-01 00:00:00

  • Concomitant pulmonary carcinoma and abdominal aortic aneurysm: therapeutic strategies.

    abstract:PURPOSE:A diagnosis of concomitant pulmonary carcinoma and abdominal aortic aneurysm is rare (<1% of treated cases). However, such an association makes the therapeutic decisions critical, especially regarding the priority and timing of treatment. This article reports on our experience of 14 cases of concomitant pulmona...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3672-0

    authors: Borzellino G,Giovinazzo F,Minicozzi AM,Dusi R,Politi L,Veraldi GF

    更新日期:2008-01-01 00:00:00

  • Indications for total esophagogastric dissociation in children with gastroesophageal reflux disease.

    abstract::Total esophagogastric dissociation (TED) is used to treat gastroesophageal reflux (GER) after failed fundoplication in neurologically impaired patients. It is now performed for some otherwise healthy patients with severe GER. In this procedure, the gastrointestinal tract is reconstructed in a non-physiological way wit...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-018-1636-9

    authors: Tanaka Y,Tainaka T,Uchida H

    更新日期:2018-11-01 00:00:00

  • Risk factors for short bowel syndrome in patients with Crohn's disease.

    abstract:PURPOSE:Patients with Crohn's disease (CD) often need home parenteral nutrition for short bowel syndrome (SBS), as a result of frequent surgery and extended bowel resections. We conducted this study to evaluate the influence of the patient's condition on the occurrence of SBS in CD. METHODS:The subjects of this study ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-011-0098-0

    authors: Uchino M,Ikeuchi H,Bando T,Matsuoka H,Takahashi Y,Takesue Y,Matsumoto T,Tomita N

    更新日期:2012-05-01 00:00:00

  • Systematic review of the feasibility and future of laparoscopic liver resection for difficult lesions.

    abstract::Laparoscopic liver resection (LLR) is now performed widely, but is difficult to accomplish in some anatomical locations, such as the posterosuperior segments (S7 and S8) and caudate lobe (S1). An international survey revealed that lesions in these locations are less frequently indicated for LLR than those in other seg...

    journal_title:Surgery today

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00595-017-1607-6

    authors: Araki K,Kubo N,Watanabe A,Kuwano H,Shirabe K

    更新日期:2018-07-01 00:00:00

  • Extended central bisegmentectomy--an en bloc resection of hepatic segments 4, 5, 8 and 7: report of a case.

    abstract::We herein present an example of an extended central bisegmentectomy in a patient with a large hepatocellular carcinoma. According to a magnetic resonance imaging study, the right hepatic vein was displaced and narrowed at its origin and a large inferior right hepatic vein was revealed. In this case, owing to the only ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02473403

    authors: Tanaka K,Nishimura A,Takenaka K,Yamada K,Ishibe R,Ogata S,Ishizaki N,Taira A

    更新日期:1994-01-01 00:00:00

  • Laparoscopic lymph node dissection around the inferior mesenteric artery for left-sided colon and rectal cancer.

    abstract::Lymph node dissection is a critical part of surgery for colorectal cancer. Japanese D3 and complete mesocolic excision are two unique principles for lymph node dissection in colorectal cancer. Laparoscopic surgery magnifies the targets and provides insight about the micro-anatomy through high-quality, high-definition ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-017-1595-6

    authors: Takahashi H,Haraguchi N,Nishimura J,Hata T,Matsuda C,Yamamoto H,Mizushima T,Doki Y,Mori M

    更新日期:2018-03-01 00:00:00

  • A patient with early gallbladder cancer derived from a Rokitanski-Aschoff sinus.

    abstract::We present herein a case of a 40-year-old male with early gallbladder cancer derived from a Rokitanski-Aschoff sinus (RAS). The patient originally presented at our hospital with epigastric discomfort, following which a diagnosis of adenomyomatosis (ADM) of the gallbladder was made, and a cholecystectomy performed. His...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00309054

    authors: Funabiki T,Matsumoto S,Tsukada N,Kimura T,Yoshizaki S,Horibe Y

    更新日期:1993-01-01 00:00:00

  • The ability of polymorphonuclear leukocytes to produce active oxygen in a model of peritonitis in rats.

    abstract::To elucidate the mechanism of enhancing survival in peritonitis rats treated with lentinan, a fully purified beta-1,3-glucan, we measured the active oxygen-producing ability of polymorphonuclear leukocytes (PMNs). Four groups of rats (group I, fecal peritonitis control; II, rats receiving 3 mg/kg lentinan intraperiton...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311908

    authors: Shen SC,Nakao A,Kishimoto W,Harada A,Nonami T,Nakano M,Takagi H

    更新日期:1993-01-01 00:00:00

  • Role of age as a prognostic factor in breast cancer.

    abstract::The effect of age on the prognosis of breast cancer remains controversial. To investigate the role of age, we reviewed 316 patients with stage I or II breast cancer. There were 14 patients below 34, 146 between 35 and 49, 115 between 50 and 65, and 41 over 66 years of age. No correlations were observed between age and...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00941647

    authors: Tsuchiya A,Abe R,Kanno M,Ohtake T,Fukushima T,Nomizu T,Kimijima I

    更新日期:1997-01-01 00:00:00

  • Complete endobronchial obstruction and left non-aerated hemithorax caused by a leiomyoma: report of a case.

    abstract::Presented herein is the case of a 27-year-old man in whom an endobronchial tumor was found causing complete obstruction of the left main bronchus. The tumor was successfully removed by performing sleeve resection of the left main bronchus without pulmonary resection, immediately following which the left lung became re...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311091

    authors: Sung DF

    更新日期:1995-01-01 00:00:00

  • Occurrence of intraperitoneal septic complications after hepatic resections between 1985 and 1990.

    abstract::In this study, the risk factors related to intraperitoneal septic complications occurring after hepatectomy (IPSCH) as well as the effect of various perioperative variables on the outcome of IPSCH between 1985 and 1990 were analyzed. Twenty-one of 211 patients (10.0%) developed IPSCH. The findings in the patients with...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00309385

    authors: Matsumata T,Yanaga K,Shimada M,Shirabe K,Taketomi A,Sugimachi K

    更新日期:1995-01-01 00:00:00

  • Diaphragmatic hernia with ischemic bowel obstruction in pregnancy: report of a case.

    abstract::Diaphragmatic hernia complicating pregnancy is rare and is associated with high morbidity and mortality, particularly if surgical intervention is delayed. We report a case of diaphragmatic hernia in a pregnant 25-year-old woman. The patient was referred to our hospital in respiratory distress in the 28th week of her p...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-007-3718-y

    authors: Sano A,Kato H,Hamatani H,Sakai M,Tanaka N,Inose T,Kimura H,Kuwano H

    更新日期:2008-01-01 00:00:00

  • Jejunal cancer detected after a resection of bilateral ovarian metastasis: report of a case.

    abstract::A 50-year-old woman was admitted to our hospital because of abdominal distension and fullness. Computed tomography and magnetic resonance imaging showed bilateral ovarian tumors. Although these ovarian tumors were suspected of being metastatic, the primary tumor site could not be detected before the bilateral salpingo...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-4174-7

    authors: Maekawa H,Sato K,Komatsu Y,Orita H,Sakurada M

    更新日期:2010-11-01 00:00:00

  • Successful perioperative management of patients with Parkinson's disease following gastrointestinal surgery: report of three cases.

    abstract::Parkinson's disease is a chronic progressive disease with symptoms of tremors, rigidity, and akinesia. Parkinson's disease is a major risk factor for postoperative complications and it is difficult to manage patients with Parkinson's disease after gastrointestinal surgery. This report presents the cases of three patie...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3938-9

    authors: Fujii T,Nakabayashi T,Hashimoto S,Kuwano H

    更新日期:2009-01-01 00:00:00

  • Risk factors for postoperative complications after gastrectomy in gastric cancer patients with comorbidities.

    abstract:PURPOSE:We conducted this retrospective cohort study to evaluate which preoperative comorbidities and their combinations are most strongly associated with postoperative complications after gastrectomy. METHODS:We collected data on 214 consecutive patients who underwent gastrectomy for gastric cancer. Preoperative como...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-015-1175-6

    authors: Hamakawa T,Kurokawa Y,Mikami J,Miyazaki Y,Takahashi T,Yamasaki M,Miyata H,Nakajima K,Takiguchi S,Mori M,Doki Y

    更新日期:2016-02-01 00:00:00

  • Limited effectiveness of FK506 administration for ongoing rejection in heterotopic rat heart transplantation.

    abstract::A comparison was made of the histological findings for myocardial tissue of heterotopic transplanted rat hearts administered with FK506. ACI rats were used as donors and Lewis rats as recipients. FK506 was used for 6 days except for group I (control group). Group II received 0.32 mg/kg/day of FK506 from the day of ope...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02032897

    authors: Hisatomi K,Sato T,Nishimi M,Hirano A,Isomura T,Aoyagi S,Kosuga K,Ohishi K

    更新日期:1994-01-01 00:00:00

  • A new preoperative grading system for predicting the operative conditions for abdominal wall-lifting laparoscopic cholecystectomy.

    abstract:PURPOSE:This study was performed to evaluate the operative conditions for an abdominal wall-lifting laparoscopic cholecystectomy (ALLC) using a new preoperative grading system. METHODS:One hundred forty-five patients who underwent a cholecystectomy for cholecystolithiasis from January 1997 to December 1999 were retros...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950200005

    authors: Takegami K,Sata N,Kawaguchi Y,Kubota Y

    更新日期:2002-01-01 00:00:00

  • Portal vein thrombosis after splenectomy successfully treated by an enormous dosage of fibrinolytic agent in a short period: report of two cases.

    abstract::Portal vein thrombosis (PVT) after splenectomy in a patient with portal hypertension occurs with unusually high frequency. Recently, two patients with PVT following splenectomy were treated by fibrinolytic therapy with an enormous dosage of urokinase (UK) in a short period. PVT was quickly dissolved without side effec...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00308800

    authors: Suzuki S,Nakamura S,Baba S,Sakaguchi S,Ohnuki Y,Yokoi Y,Nishiyama R

    更新日期:1992-01-01 00:00:00

  • Laparotomy versus interventional radiological procedures for the implantation of arterial infusion devices.

    abstract::Although there have been numerous reports on implantable infusion devices for chemotherapy of patients with malignancy, we occasionally face problems with this therapy due to trouble with implantation. We performed a retrospective review of 81 implantations in 77 patients, who were treated with intraarterial chemother...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02385701

    authors: Matsuda T,Yamagishi H,Jin MB,Kobayashi Y,Sonoyama T,Oka T

    更新日期:1997-01-01 00:00:00