Abstract：
BACKGROUND/PURPOSE:The aim of this study was to establish a prenatal prognostic classification system for risk-stratified management in fetuses with isolated congenital diaphragmatic hernia (CDH). METHODS:A multi-institutional retrospective cohort study of isolated CDH, diagnosed prenatally in fetuses delivered during the 2002 to 2007 period at 5 participating institutions in Japan, was conducted. The risk stratification system was formulated based on the odds ratios of prenatal parameters for mortality at 90 days. The clinical severity in CDH infants were compared among the stratified risk groups. RESULTS:Patients were classified into the 3 risk groups: group A (n = 48) consisted of infants showing liver-down with contralateral lung-to-thorax transverse area ratio (L/T) ratio ≥0.08; group B of infants showing liver-down with L/T ratio <0.08 or liver-up with L/T ratio ≥0.08 (n = 35), and group C of infants showing liver-up with L/T ratio <0.08 (n = 20). The mortality at 90 days in groups A, B, and C were 0.0%, 20.0%, and 65.0%, respectively. The intact discharge rates were 95.8%, 60.0%, and 5.0%, respectively. This system also accurately reflected the clinical severity in CDH infants. CONCLUSIONS:Our prenatal risk stratification system, which demonstrated a significant difference in postnatal status and final outcome, would allow for accurate estimation of the severity of disease in fetuses with isolated CDH, although it needs prospective validation in a different population.
journal_name
J Pediatr Surgjournal_title
Journal of pediatric surgeryauthors
Usui N,Kitano Y,Okuyama H,Saito M,Masumoto K,Morikawa N,Takayasu H,Nakamura T,Hayashi S,Kawataki M,Ishikawa H,Nose K,Inamura N,Sago Hdoi
10.1016/j.jpedsurg.2011.06.007subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1873-80issue
10eissn
0022-3468issn
1531-5037pii
S0022-3468(11)00537-9journal_volume
46pub_type
杂志文章,多中心研究abstract：PURPOSE:Cloacal exstrophy is a rare and complex congenital anomaly requiring coordination among multiple pediatric subspecialties. There is currently no consensus regarding the fate and function of the hindgut, which plays an integral role in patients' long-term gastrointestinal health and genitourinary reconstruction....
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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abstract：:Extracorporeal membrane oxygenation (ECMO) has been used for 20 years in neonates and children with cardiac and respiratory failure. The number of neonates treated with ECMO has increased exponentially, but the number of older children treated is small. The selection and exclusion criteria for pediatric ECMO are poorl...
journal_title：Journal of pediatric surgery
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doi：10.1016/0022-3468(91)90511-q
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abstract：:Gastrointestinal manifestations of collagen diseases are very rare. The authors report on a patient who has features of Marfan syndrome with mobile liver caused by the absence of its suspensory ligaments. This patient presented with an acute intestinal obstruction secondary to a congenital band across the distal trans...
journal_title：Journal of pediatric surgery
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abstract：BACKGROUND:During recovery from intestinal ischemic injury, there is rapid growth of intestinal epithelia with regeneration of damaged villi. This study examines the effects of heparin-binding EGF-like growth factor (HB-EGF) on the recovery of intestinal epithelial cells exposed to hypoxia. METHODS:The cytoprotective ...
journal_title：Journal of pediatric surgery
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doi：10.1016/s0022-3468(98)90517-6
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abstract：BACKGROUND/PURPOSE:This study aims to elucidate the clinical presentation, the effectiveness of investigations, and treatment of foreign body ingestion in children and to formulate an algorithm of management. METHODS:The records of children admitted to a single institution who had a history of foreign body ingestion o...
journal_title：Journal of pediatric surgery
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abstract：:Only one third of the applicants for training in pediatric surgery obtain a position through the pediatric surgery matching program. In order to identify factors that contribute to a successful outcome, we conducted a retrospective survey of all participants in the matching process for positions during the years 1983 ...
journal_title：Journal of pediatric surgery
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更新日期：1992-02-01 00:00:00
abstract：PURPOSE:The aim of this study was to investigate the prenatal courses and management of abdominal surgical diseases. METHODS:Of the 327 patients registered with our fetal treatment board since March 2002, 83 fetuses referred to the surgical department were enrolled for the current study. The prenatal diagnosis, sequen...
journal_title：Journal of pediatric surgery
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abstract：:For infants with omphalocele, the size of the defect and the presence of associated anomalies are well known prognostic factors. However, the prognostic importance of the respiratory status at birth has not been well defined. The authors reviewed the records of 30 infants with omphalocele (treated during a 10-year per...
journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jpedsurg.2014.10.046
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abstract：:The ability of external imaging to demonstrate intestinal infarction in neonatal necrotizing enterocolitis (NEC) was prospectively evaluated. The radiopharmaceutical technetium--99m diphosphonate was injected intravenously and the patients subsequently underwent abdominal scanning. Clinical patient care and interpreta...
journal_title：Journal of pediatric surgery
pub_type： 临床试验,杂志文章
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：2011-06-01 00:00:00
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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更新日期：2013-10-01 00:00:00
abstract：BACKGROUND/PURPOSE:The U.S. has an alarming rate of firearm injuries. Racial disparities among victims and predictors of outcomes are not well established. Our objective was to assess costs, length of stay (LOS), and inpatient mortality among nonfatal and fatal pediatric firearm injuries that required hospitalization. ...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2020.02.021
更新日期：2020-08-01 00:00:00
abstract：:From 1958 to March 1987 we corrected 704 patients with pectus excavatum. The condition occurred more frequently in boys (544 patients) than girls (160 patients). In the majority of patients (86%), the defect was evident at birth or within the first year of life. Musculoskeletal abnormalities were identified in 133 pat...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(88)80629-8
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abstract：BACKGROUND:Crossed fused renal ectopia (CFRE) is a rare congenital malformation. Renal bladder ultrasound (RBUS) is a good tool for establishing the diagnosis, however, additional imaging with a voiding cystourethrogram (VCUG) and dimercaptosuccinic acid scan (DMSA) might be required. We assessed the need for postnatal...
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doi：10.1016/j.jpedsurg.2020.08.030
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abstract：BACKGROUND:Hepatoblastoma (HB) is a highly malignant primary liver tumor in children. Although liver transplantation (LT) is an effective treatment for unresectable HB with good long-term outcomes, post-transplant survival is mainly affected by recurrence, despite adjuvant chemotherapy. Novel strategies are needed to i...
journal_title：Journal of pediatric surgery
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doi：10.1016/j.jpedsurg.2016.04.021
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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abstract：:Extrahepatic portal hypertension was induced in rats by portal venous constriction. Portal pressures on the fourth postconstriction day were significantly elevated in PVC rats when compared to control rats. Splenoportograms showed decreased hepatic flow and venous collaterals. Histologic sections showed gastric mucosa...
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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abstract：:The existence of Helicobacter pylori (HP) infection in those children who had previous bladder augmentation with gastric patch has not been described before. In this report, a girl with bladder exstrophy, who previously underwent gastric augmentation is presented. She had multiple admissions to our unit with persistin...
journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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更新日期：2001-01-01 00:00:00
