The global Edoxaban Treatment in routine cliNical prActice (ETNA) noninterventional study program: rationale and design.

abstract：BACKGROUND:Percutaneous interventions for aorto-ostial narrowing of native coronary arteries are challenging because of early elastic recoil after the procedure and the high restenosis rate. Cutting balloon angioplasty may reduce this complication. HYPOTHESIS:The purpose of the study was to evaluate the clinical outco...

journal_title：Clinical cardiology

authors： Nassar H,Gotsman I,Gerganski P,Moseri M,Lotan C,Gotsman M

更新日期：2009-04-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is a major independent risk factor for cardiovascular disease, and diabetic dyslipidemia is a major contributor to cardiovascular risk in these patients. Here we report the rationale and design of a phase 3, double-blind study specifically designed to evaluate the lipid-lowering efficac...

journal_title：Clinical cardiology

authors： Lorenzatti AJ,Eliaschewitz FG,Chen Y,Fialkow J,Lu J,Baass A,Monsalvo ML,Hsu HC,Somaratne R,Ge J

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Marfan's syndrome is an inherited disorder of connective tissue associated with characteristic abnormalities of the skeletal, ocular, and cardiovascular systems. Marked clinical variability and age dependency of all manifestations of Marfan's syndrome may render the unequivocal diagnosis difficult in mildly ...

journal_title：Clinical cardiology

authors： Mercuro G,Carpiniello B,Ruscazio M,Zoncu S,Montisci R,Rudas N,Cherchi A

更新日期：1997-03-01 00:00:00

abstract：:K-strophanthin or digoxin were added to diuretics (all cases) and vasodilators (most cases) for treating advanced congestive heart failure in 22 patients with dilated cardiomyopathy and sinus rhythm. K-strophanthin (0.125 mg intravenously) or digoxin (0.25 mg orally) were administered daily in two 3-month periods, dur...

journal_title：Clinical cardiology

authors： Agostoni PG,Doria E,Berti M,Guazzi MD

更新日期：1994-10-01 00:00:00

abstract：:Dynamic cardiomyoplasty is a new surgical procedure proposed for treatment of the failing heart. Clinically, the latissimus dorsi muscle is raised as a pedicled flap and wrapped around the heart. The skeletal muscle is transformed to produce a myocardium-like fatigue-resistant muscle. It is stimulated to contract in s...

journal_title：Clinical cardiology

authors： Hill AB,Chiu RC

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:The incidence of congestive heart failure (CHF) has not significantly declined over the past 50 years, and overall survival rates are low at 5 years following diagnosis. Numerous studies have shown low serum sodium to be a poor prognostic indicator of all cause mortality in CHF patients. HYPOTHESIS:The goal...

journal_title：Clinical cardiology

authors： DeWolfe A,Lopez B,Arcement LM,Hebert K

更新日期：2010-12-01 00:00:00

abstract：:The pharmacologic management of the patient post myocardial infarction (MI) aims to achieve several goals. Chief among these is to prevent subsequent events, which include death, reinfarction, and rehospitalization. Secondary goals include preventing arrhythmias, minimizing left ventricular (LV) remodeling, and preven...

journal_title：Clinical cardiology

authors： Reiffel JA,American Heart Association.,American College of Cardiology.

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Carotid artery stenting (CAS) is increasingly used for treatment of severe carotid artery stenosis, but only few procedural risk factors for complications of CAS are clearly defined yet. A possible impact of the patient's gender on the outcome of patients undergoing CAS has not been investigated properly and...

journal_title：Clinical cardiology

authors： Werner N,Zeymer U,Mark B,Hochadel M,Hauptmann KE,Jung J,Hoffmann E,Elsässer A,Fürste T,Leschke M,Mudra H,Zahn R,Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK).

更新日期：2012-02-01 00:00:00

abstract：:Recent clinical investigations have provided new insights into physiologic alterations taking place as heart failure progresses. As a result, new end points may be more relevant to monitor in patients, rather than the classical assessment of severity based on subjective evaluation of functional capacity. Structural ch...

journal_title：Clinical cardiology

authors： Cohn JN

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Myocardial perfusion imaging (MPI) provides incremental diagnostic and prognostic information, even in patients with high exercise tolerance. HYPOTHESIS:Myocardial perfusion imaging provides significant diagnostic value, specifically in women with high exercise tolerance. METHODS:Our study population consi...

journal_title：Clinical cardiology

authors： Chatziioannou SN,Moore WH,Dhekne RD,Ford PV

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the relationship between left atrial (LA) myocardial function and left ventricular (LV) diastolic dysfunction in subjects with preserved LV ejection fraction (LVEF). METHODS:The study included a group of 118 hypertensive patients and normal subjects. LV diastolic...

journal_title：Clinical cardiology

authors： Guan Z,Zhang D,Huang R,Zhang F,Wang Q,Guo S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Recent data suggests that low molecular weight heparins (LMWHs) may be superior to unfractionated heparin (UFH) as an adjunct to fibrinolytic therapy in patients with acute ST-segment elevation myocardial infarction (STEMI). HYPOTHESIS:We evaluated cardiac outcomes and the risk of major bleeding with LMWHs ...

journal_title：Clinical cardiology

authors： Singh S,Bahekar A,Molnar J,Khosla S,Arora R

更新日期：2009-07-01 00:00:00

abstract：:Since the initial report of balloon coarctation angioplasty in 1982, several workers used this technique in native coarctation and postoperative recoarctation. Immediate and intermediate-term follow-up results are generally good with a small chance for recoarctation and aneurysmal formation at the site of coarctation....

journal_title：Clinical cardiology

authors： Rao PS

更新日期：1989-11-01 00:00:00

abstract：:Severe aortic regurgitation may be associated with premature aortic valve opening. Several possible etiologies for this diastolic opening have been suggested. We present a patient with hemodynamic data, M-mode and 2-D echocardiography in the setting of severe aortic regurgitation and diastolic aortic valve opening. Ou...

journal_title：Clinical cardiology

authors： Martinez EE,Herman MV,Kay RH,Pontes SC Jr,Brandao AC,Pfefferman A,Arroyo JB,Portugal OP

更新日期：1986-05-01 00:00:00

abstract：:Fourteen morbidly obese patients scheduled for gastric bypass surgery were diagnosed preoperatively as suffering from sleep apnea syndrome. There were 13 males and 1 female aged 24 to 59 years. Mean preoperative excessive body weight was 222 +/- 38%; mean apnea index prior to surgery was 84 +/- 44. A whole night lead ...

journal_title：Clinical cardiology

authors： Peiser J,Ovnat A,Uwyyed K,Lavie P,Charuzi I

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:An experimental study showed that nebivolol is an effective agent in contrast-induced nephropathy (CIN) prophylaxis. HYPOTHESIS:We hypothesized that prophylactic nebivolol use had protective effects on renal function in human beings subjected to iodinated contrast agent since it has vasodilatory effect and ...

journal_title：Clinical cardiology

authors： Günebakmaz O,Kaya MG,Koc F,Akpek M,Kasapkara A,Inanc MT,Yarlioglues M,Calapkorur B,Karadag Z,Oguzhan A

更新日期：2012-04-01 00:00:00

abstract：:Dobutamine stress echocardiography (DSE) is a reliable cardiac risk stratifier that has widespread applicability because of its clinical accuracy and cost effectiveness. Dobutamine has positive inotropic and chronotropic effects and is commonly used in patients who cannot exercise or achieve an adequate heart rate res...

journal_title：Clinical cardiology

authors： Usher BW Jr,O'Brien TX

更新日期：2000-08-01 00:00:00

abstract：:Rapid assessment of patients presenting with acute chest pain is essential, in order to distinguish between those who have a life-threatening condition, such as myocardial infarction or unstable angina, and the substantial proportion who do not have an acute coronary syndrome. It is thus of vital importance that relia...

journal_title：Clinical cardiology

authors： Husted SE

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Familial hypercholesterolemia (FH) is a common autosomal dominant disease associated with premature coronary heart disease (CHD). Studies tend to show that patients with FH associated with an identified mutation (mutation+ FH) are at higher risk than patients without an identified mutation (mutation- FH). We...

journal_title：Clinical cardiology

authors： Séguro F,Rabès JP,Taraszkiewicz D,Ruidavets JB,Bongard V,Ferrières J

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Stimulated endothelium-derived relaxing factor-mediated vasodilation and conduit artery distensibility are impaired in congestive heart failure (CHF). L-arginine could have a potentially beneficial role in CHF, acting through the nitric oxide (NO)-L-arginine pathway or by growth hormone increment. HYPOTHESI...

journal_title：Clinical cardiology

authors： Bocchi EA,Vilella de Moraes AV,Esteves-Filho A,Bacal F,Auler JO,Carmona MJ,Bellotti G,Ramires AF

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Cardiac contractility modulation (CCM) is an electrical-device therapy for patients with heart failure with reduced ejection fraction (HFrEF). Patients with left ventricular ejection fraction (LVEF) ≤35% also have indication for an implantable cardioverter-defibrillator (ICD), and in some cases subcutaneous ...

journal_title：Clinical cardiology

authors： Röger S,Rudic B,Akin I,Shchetynska-Marinova T,Fastenrath F,Tülümen E,Liebe V,El-Battrawy I,Baumann S,Kuschyk J,Borggrefe M

更新日期：2018-04-01 00:00:00

abstract：:The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM). We evaluated left ventricular hypertrophy by means of two-dimensional echocardiographic score and score index, and correlated these findings with symptoms, electrovector-c...

journal_title：Clinical cardiology

authors： Melacini P,Fasoli G,Canciani B,Buja G,Mammola C,Volta SD

更新日期：1989-08-01 00:00:00

abstract：:Several investigators have documented the successful use of oral sustained-release theophylline in treating symptomatic bradycardia and sick sinus syndrome. This paper reports a case of chronotropic incompetence in which specific exercise indices, including the chronotropic response index, were used to measure the the...

journal_title：Clinical cardiology

authors： Dixon WC 4th,Bauch TD

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Ablation procedures in patients with paroxysmal atrial fibrillation (PAF) includes isolation of all pulmonary veins (PVs). We hypothesized that an approach using an algorithm to detect arrhythmogenic PVs (aPVs) might lead to shorter procedure duration (PD) and fewer proarrhythmic effects (PE). HYPOTHESIS:Is...

journal_title：Clinical cardiology

authors： Fichtner S,Hessling G,Ammar S,Reents T,Estner HL,Jilek C,Kathan S,Büchner M,Dillier R,Deisenhofer I

更新日期：2013-07-01 00:00:00

abstract：:Warfarin and other 4-hydroxycoumarins are effective antithrombotic agents. They affect four blood coagulation proteins that act sequentially to produce thrombin. Coumarin therapy decreases the biological activity of these proteins, and therefore decreases the rate at which blood clots. As the mechanism by which these ...

journal_title：Clinical cardiology

authors： Suttie JW

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Despite a high prevalence of hypertension in the population with CAD, there are limited data describing the clinical characteristics and treatments, as well as their interrelations in these patients. This is particularly true for black and Hispanic patients who have been underrepresented in randomized CAD tr...

journal_title：Clinical cardiology

authors： Cooper-DeHoff RM,Handberg EM,Cohen J,Kowey P,Messerli FH,Mancia G,Cangiano JL,Gaxiola E,Garcia-Barreto D,Hewkin AC,Pepine CJ,INVEST Investigators.

更新日期：2004-10-01 00:00:00

abstract：:The Randomized Endo-vein Graft Prospective (REGROUP) trial (ClinicalTrials.gov NCT01850082) is a randomized, intent-to-treat, 2-arm, parallel-design, multicenter study funded by the Cooperative Studies Program (CSP No. 588) of the US Department of Veterans Affairs. Cardiac surgeons at 16 Veterans Affairs (VA) medical ...

journal_title：Clinical cardiology

authors： Zenati MA,Gaziano JM,Collins JF,Biswas K,Gabany JM,Quin JA,Bitondo JM,Bakaeen FG,Kelly RF,Shroyer AL,Bhatt DL

更新日期：2014-06-01 00:00:00

abstract：:We describe two patients in whom spontaneous angina following acute myocardial infarction (postinfarction angina caused by coronary artery spasm) and worsening angina were successfully eliminated after clinical dosage of oral diltiazem, while marked sinus node suppression developed and temporary pacing was performed. ...

journal_title：Clinical cardiology

authors： Ishikawa T,Imamura T,Koiwaya Y,Tanaka K

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Compared with medical therapy, percutaneous coronary intervention (PCI) does not reduce mortality or myocardial infarction in patients with stable angina. Therefore, PCI should be guided by refractory anginal symptoms and not just lesion characteristics. HYPOTHESIS:We hypothesized that angiographic lesion c...

journal_title：Clinical cardiology

authors： Atreya AR,Sivalingam SK,Arora S,Kashef MA,Fitzgerald J,Visintainer P,Lotfi A,Rothberg MB

更新日期：2016-04-01 00:00:00

abstract：:Despite advances in the treatment of congestive heart failure (CHF), the mortality rate continues to be high. A large number of the deaths are sudden, presumably due to ventricular arrhythmias. Complex ventricular arrhythmias are recorded in as many as 80% of patients with CHF, with nonsustained ventricular tachycardi...

journal_title：Clinical cardiology

authors： Chakko S,de Marchena E,Kessler KM,Myerburg RJ

更新日期：1989-09-01 00:00:00