当前位置： SCI文献检索 > SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY期刊下所有文献 > Accuracy of clinical prediction rules in peptic ulcer perforation: an observational study.

Accuracy of clinical prediction rules in peptic ulcer perforation: an observational study.

Abstract：

OBJECTIVE:The aim of the present study was to compare the ability of four clinical prediction rules to predict adverse outcome in perforated peptic ulcer (PPU): the Boey score, the American Society of Anesthesiologists (ASA) score, the Acute Physiology and Chronic Health Evaluation (APACHE) II score, and the sepsis score. MATERIAL AND METHODS: DESIGN:an observational multicenter study. PARTICIPANTS AND SETTINGS:a total of 117 patients surgically treated for PPU between 1 January 2008 and 31 December 2009 in seven gastrointestinal departments in Denmark were included. Pregnant and breastfeeding women, non-surgically treated patients, patients with malignant ulcers, and patients with perforation of other organs were excluded. PRIMARY OUTCOME MEASURE:30-day mortality rate. STATISTICAL ANALYSIS:the ability of four clinical prediction rules to distinguish survivors from non-survivors (discrimination ability) was evaluated by the area under the receiver operating characteristic curve (AUC), positive predictive values (PPVs), negative predictive values (NPVs), and adjusted relative risks. RESULTS:Median age (range) was 70 years (25-92 years), 51% of the patients were females, and 73% of the patients had at least one co-existing disease. The 30-day mortality proportion was 17% (20/117). The AUCs: the Boey score, 0.63; the sepsis score, 0.69; the ASA score, 0.73; and the APACHE II score, 0.76. Overall, the PPVs of all four prediction rules were low and the NPVs high. CONCLUSIONS:The Boey score, the ASA score, the APACHE II score, and the sepsis score predict mortality poorly in patients with PPU.

journal_name

Scand J Gastroenterol

journal_title

Scandinavian journal of gastroenterology

authors

Buck DL,Vester-Andersen M,Møller MH

doi

10.3109/00365521.2011.639078

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

28-35

issue

1

eissn

0036-5521

issn

1502-7708

journal_volume

47

pub_type

杂志文章,多中心研究

相关文献

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY文献大全
  • TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas.

    abstract：BACKGROUND:Bile duct and pancreatic cancer (PC) have poor prognoses and treatment options for inoperable patients are scarce. In order to improve outcome for these patients, there is an urgent need for biomarkers predictive of treatment effect. Irinotecan is a topoisomerase 1 (Top1) poison. Top1 protein, TOP1 gene copy...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365521.2014.980318

    authors： Grunnet M,Calatayud D,Schultz NA,Hasselby JP,Mau-Sørensen M,Brünner N,Stenvang J

    更新日期：2015-04-01 00:00:00

  • No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer.

    abstract：BACKGROUND:The DNA mismatch repair gene mutations underlying hereditary non-polyposis colorectal cancer syndrome (HNPCC) also predispose, besides colorectal and endometrial cancer, to gastric cancer. usually of the intestinal type. The carcinogenetic pathway behind the elevated gastric cancer risk is largely unknown. ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520252903134

    authors： Renkonen-Sinisalo L,Sipponen P,Aarnio M,Julkunen R,Aaltonen LA,Sarna S,Järvinen HJ,Mecklin JP

    更新日期：2002-05-01 00:00:00

  • Oesophagitis, signs of reflux, and gastric acid secretion in patients with symptoms of gastro-oesophageal reflux disease.

    abstract：:In a study comprising 100 patients referred to a surgical clinic with symptoms suggestive of gastro-oesophageal reflux disease the value of different diagnostic procedures was investigated. Positive acid perfusion and 24-h pH tests were the commonest findings. Forty-nine per cent showed a normal oesophageal mucosa or ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365528609011128

    authors： Johansson KE,Ask P,Boeryd B,Fransson SG,Tibbling L

    更新日期：1986-09-01 00:00:00

  • Differences in the intrinsic capacity of peripheral blood mononuclear cells to produce tumor necrosis factor alpha and beta in patients with inflammatory bowel disease and healthy controls.

    abstract：BACKGROUND:Tumor necrosis factor alpha (TNF alpha) and beta (TNF beta) appear to play an important role in the regulation of the inflammatory response. The aim of the present study was to investigate the intrinsic capacity of peripheral blood mononuclear cells (PBMC) to produce these cytokines. METHODS:PBMC from 41 pa...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365529509101613

    authors： Bouma G,Oudkerk Pool M,Scharenberg JG,Kolkman JJ,von Blomberg BM,Scheper RJ,Meuwissen SG,Peña AS

    更新日期：1995-11-01 00:00:00

  • Protective effects of N-acetyl-L-cysteine and platelet activating factor inhibition are not linked to intercellular adhesion molecule-1 expression after intestinal ischemia and reperfusion injury in rats.

    abstract：BACKGROUND:Intestinal ischemia and reperfusion (I/R) injury may result in development of the systemic inflammatory response syndrome (SIRS). The interactions between activated leukocytes and endothelial cells, mediated by adhesion molecules, seem to be pivotal in these conditions, leading as they do to extravasation of...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520310002201

    authors： Olanders K,Börjesson A,Sun ZW,Andersson R

    更新日期：2003-06-01 00:00:00

  • Gastrin secretion before and after gastric bypass surgery for morbid obesity.

    abstract：:Fasting, meal-stimulated, and insulin-hypoglycemia-stimulated serum gastrin levels were measured before and 3 and 12 months after gastric bypass surgery in nine obese patients. The basal gastrin concentration was unaffected by the operation. After a meal both serum gastrin and blood glucose levels were significantly i...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365528109180995

    authors： Schrumpf E,Giercksky KE,Nygaard K,Fausa O

    更新日期：1981-01-01 00:00:00

  • Anti-CagA and anti-VacA antibodies in Helicobacter pylori-infected patients with and without peptic ulcer disease in Serbia and Montenegro.

    abstract：BACKGROUND:The expression of two Helicobacter pylori proteins, CagA and VacA, is associated with more severe pathogenesis and clinical outcomes of the infection. However, this association varies among geographical regions and ethnic groups. We therefore evaluated CagA and VacA seroprevalence in H. pylori-positive dyspe...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520310008403

    authors： Sokic-Milutinovic A,Wex T,Todorovic V,Milosavljevic T,Malfertheiner P

    更新日期：2004-03-01 00:00:00

  • Enzyme activities in human gastric mucosa in gastritis and resected stomachs.

    abstract：:Biopsy specimens from the antral and body part of the stomach were studied for a range of marker enzymes in 11 patients with superficial gastritis, 9 patients with atrophic gastritis, and 31 Billroth-II-resected patients and compared with activities found in controls with normal gastric mucosa. In the antral part of t...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365528608996452

    authors： Odegaard S,Børkje B,Skagen DW,Laerum OD,Schrumpf E

    更新日期：1986-12-01 00:00:00

  • Constipation assessed on the basis of colorectal physiology.

    abstract：BACKGROUND:Constipation is a collective term for symptoms of different aetiologies and pathophysiologies. Our aim was to determine the prevalence of colorectal pathophysiology findings in a prospective series of patients with chronic constipation. METHODS:A total of 155 consecutive patients with chronic constipation u...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365529850172359

    authors： Glia A,Lindberg G,Nilsson LH,Mihocsa L,Akerlund JE

    更新日期：1998-12-01 00:00:00

  • Invasive and non-invasive diagnosis of Helicobacter pylori-associated atrophic gastritis: a comparative study.

    abstract：OBJECTIVE:Helicobacter pylori-associated atrophic gastritis is known to be a significant risk factor for gastric cancer. Among the well-known parameters of atrophic gastritis are the levels of serum gastrin-17 (G-17) and pepsinogen I (PG1), which are biomarkers of gastric antral and corpus mucosal activity, respectivel...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520410010607

    authors： Pasechnikov VD,Chukov SZ,Kotelevets SM,Mostovov AN,Mernova VP,Polyakova MB

    更新日期：2005-03-01 00:00:00

  • DNA ploidy, S-phase fraction, and G2 fraction as prognostic determinants in human pancreatic cancer.

    abstract：:The DNA ploidy, S-phase fraction (SPF), and G2 fraction of pancreatic cancer tissue was measured by flow cytometry in 95 patients. Forty-nine per cent (n = 47) had a diploid DNA index, and 51% (n = 48) of tumours were aneuploid. Aneuploid tumours and high-grade tumours had significantly higher S-phase and G2-fraction ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365529209011164

    authors： Eskelinen M,Lipponen P,Marin S,Haapasalo H,Mäkinen K,Puittinen J,Alhava E,Nordling S

    更新日期：1992-01-01 00:00:00

  • Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphism in alcohol liver cirrhosis and alcohol chronic pancreatitis among Polish individuals.

    abstract：OBJECTIVE:To investigate the effects of ADH and ALDH gene polymorphism on the development of alcoholism, alcohol liver cirrhosis and alcohol chronic pancreatitis among Polish individuals. MATERIAL AND METHODS:We determined the allele and genotype of ADH2, ADH3 and ALDH2 in 198 subjects: 57 with alcohol cirrhosis, 44 w...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520600965723

    authors： Cichoz-Lach H,Partycka J,Nesina I,Celinski K,Slomka M,Wojcierowski J

    更新日期：2007-04-01 00:00:00

  • Eosinophilic gastroenteritis: our recent experience: one-year experience of atypical onset of an uncommon disease.

    abstract：:Eosinophilic gastroenteritis is an unusual entity that is rarely found in daily clinical practise. Its aetiology is unknown and diagnosis can be made microscopically with evidence of massive eosinophilic infiltration in patients with chronic gastrointestinal symptoms, excluding entities that may cause such findings (p...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/003655201317097254

    authors： Redondo-Cerezo E,Cabello MJ,González Y,Gómez M,García-Montero M,de Teresa J

    更新日期：2001-12-01 00:00:00

  • Selective inhibitors of COX-2--are they safe for the stomach?

    abstract：:NSAIDs are widely used and beneficial for patients with inflammatory pain. However, NSAIDs cause significant adverse upper gastrointestinal effects, including increased mortality from serious ulcer complications. NSAIDs exert their anti-inflammatory effects by inhibiting the activity of the COX enzyme, which was recen...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,评审

    doi：10.1080/003655200750056565

    authors： Giercksky KE,Haglund U,Rask-Madsen J

    更新日期：2000-11-01 00:00:00

  • Randomized clinical trial: inhibition of the TRPV1 system in patients with nonerosive gastroesophageal reflux disease and a partial response to PPI treatment is not associated with analgesia to esophageal experimental pain.

    abstract：OBJECTIVE:Many patients with nonerosive reflux disease (NERD) have insufficient relief on proton pump inhibitors (PPIs). Some patients have a hypersensitive esophagus and may respond to transient receptor potential vanilloid 1 (TRPV1) antagonists. Aim. To investigate the effect of the TRPV1 antagonist AZD1386 on experi...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,随机对照试验

    doi：10.3109/00365521.2012.758769

    authors： Krarup AL,Ny L,Gunnarsson J,Hvid-Jensen F,Zetterstrand S,Simrén M,Funch-Jensen P,Hansen MB,Drewes AM

    更新日期：2013-03-01 00:00:00

  • A single vial is enough in the absence of endoscopic suspected intestinal metaplasia - less is more!

    abstract：:Background: For the correct staging of chronic atrophic gastritis (AG) and gastric intestinal metaplasia (GIM) at least 4 biopsies are recommended: 2 from the antrum/incisura and 2 from the body sent in two different vials. As virtual chromoendoscopy with narrow-band-imaging (NBI) is valid both in the diagnosis and st...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,多中心研究

    doi：10.1080/00365521.2019.1613443

    authors： Castro R,Esposito G,Libânio D,Afonso L,Annibale B,Dinis-Ribeiro M,Pimentel-Nunes P

    更新日期：2019-05-01 00:00:00

  • Symptom profiles in chronic peptic ulcer disease. A detailed study of abdominal and mental symptoms.

    abstract：:Abdominal and mental symptoms were assessed in 103 outpatients with chronic peptic ulcer disease. Patients with present symptoms and a history of duodenal or prepyloric ulcer were included if they had no other disorder requiring treatment. A normal female population was used for comparison of mental symptoms. Besides ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 临床试验,杂志文章

    doi：10.3109/00365528509089674

    authors： Sjödin I,Svedlund J,Dotevall G,Gillberg R

    更新日期：1985-05-01 00:00:00

  • The immunization status of patients with IBD is alarmingly poor before the introduction of specific guidelines.

    abstract：INTRODUCTION:With immunosuppressive therapy of inflammatory bowel diseases (IBDs) becoming more aggressive, the risk of serious infections is increasing. Guidelines are currently being modified in respect to advisable immunizations. The aim of this study was to evaluate the immunization habits of IBD patients in daily ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365521.2011.574734

    authors： Wilckens V,Kannengiesser K,Hoxhold K,Frenkel C,Kucharzik T,Maaser C

    更新日期：2011-07-01 00:00:00

  • Regional variations in total and nonprotein sulfhydryl compounds in the human gastric mucosa and effects of ethanol.

    abstract：:This study evaluated the regional distribution of sulfhydryl compounds in the human gastric mucosa and the effect of ethanol on gastric sulfhydryl tissue levels. Total sulfhydryl, glutathione, and cysteine and their oxidized forms were measured in biopsy specimens taken from the gastric body and antrum of 22 healthy v...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365529109003954

    authors： Loguercio C,Romano M,Di Sapio M,Nardi G,Taranto D,Grella A,Del Vecchio Blanco C

    更新日期：1991-10-01 00:00:00

  • Chronic perineal fistula as a late failure manifestation of pseudomyxoma peritonei syndrome.

    abstract：:Pseudomyxoma peritonei syndrome (PMP) is a rare but fascinating entity in surgical oncology. It consists of the accumulation of mucus in the peritoneal cavity, sometimes in huge amounts, in most of the cases after rupture of an appendiceal tumor. The diagnosis and management of PMP has changed significantly in the pas...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520410003623

    authors： Sebbag G,Sugarbaker PH,Walfisch S,Levy I

    更新日期：2004-11-01 00:00:00

  • Benign recurrent intrahepatic cholestasis: review and long-term follow-up of five cases.

    abstract：OBJECTIVE:Benign recurrent intrahepatic cholestasis (BRIC) is a rare autosomal recessive inherited disorder characterized by intermittent episodes of cholestatic jaundice. For the patients, the disease is a physical and psychological challenge. There is no curable treatment, but symptomatic relief is described followin...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,评审

    doi：10.3109/00365521.2011.650191

    authors： Folvik G,Hilde O,Helge GO

    更新日期：2012-04-01 00:00:00

  • Spider angiomas in patients with liver cirrhosis: role of alcoholism and impaired liver function.

    abstract：BACKGROUND:Spider angioma is a common sign in patients with liver cirrhosis, but the pathogenesis is still unclear. Alcohol and hyperestrogenemia are both possible etiologies. This study was designed to investigate the relationship of spider angiomas in patients with liver cirrhosis to alcohol, liver function test resu...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/003655299750026272

    authors： Li CP,Lee FY,Hwang SJ,Chang FY,Lin HC,Lu RH,Hou MC,Chu CJ,Chan CC,Luo JC,Lee SD

    更新日期：1999-05-01 00:00:00

  • Low liver stiffness among cirrhotic patients with hepatitis B after prolonged treatment with nucleoside analogs.

    abstract：OBJECTIVE:Case reports and short-term clinical trials have suggested that treatment for chronic hepatitis B (CHB) may lead to improvement of cirrhosis. The aim of the present study was to measure liver stiffness in patients diagnosed with advanced fibrosis or cirrhosis prior to prolonged treatment with nucleoside or nu...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,多中心研究

    doi：10.3109/00365521.2011.565068

    authors： Andersen ES,Weiland O,Leutscher P,Krarup H,Westin J,Moessner B,Konopski Z,Frigstad SO,Kjær M,Christensen PB,Weis N

    更新日期：2011-06-01 00:00:00

  • Quality of life in short-bowel syndrome: impact of fatigue and gastrointestinal symptoms.

    abstract：OBJECTIVE:Patients with short-bowel syndrome (SBS) have impaired health-related quality of life (QoL). However, comparisons of QoL data with the data on other chronic gastrointestinal diseases are not available. The aim of this study was to assess QoL in SBS patients compared with that in the general population and wit...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520802078325

    authors： Kalaitzakis E,Carlsson E,Josefsson A,Bosaeus I

    更新日期：2008-01-01 00:00:00

  • Diagnostic value of endoscopy for the diagnosis of giardiasis and other intestinal diseases in patients with persistent diarrhea from tropical or subtropical areas.

    abstract：OBJECTIVE:Upper endoscopy has been suggested as a valuable tool in the diagnosis of giardiasis. The aim of this study was to compare two methods based on endoscopy, i.e. microscopy of duodenal fluid and histology, with a fluorescent-antibody assay for the detection of Giardia lamblia cysts in stool specimens. The role ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520600881193

    authors： Wahnschaffe U,Ignatius R,Loddenkemper C,Liesenfeld O,Muehlen M,Jelinek T,Burchard GD,Weinke T,Harms G,Stein H,Zeitz M,Ullrich R,Schneider T

    更新日期：2007-03-01 00:00:00

  • A comparison between in vitro jejunal mast cell degranulation and intragastric challenge in patients with suspected food intolerance.

    abstract：:Fifteen patients with suspected food intolerance were investigated. Ten patients showed a positive reaction to double-blind intragastric food challenge. Mast cell degranulation induced by in vitro challenge with foods or food antigens on mucosal specimens corresponded well with the results of intragastric food challen...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 临床试验,杂志文章

    doi：10.3109/00365528509091654

    authors： Selbekk BH

    更新日期：1985-04-01 00:00:00

  • Cholecystokinin in the control of gastric acid secretion and gastrin release in response to a meal at low and high pH in healthy subjects and duodenal ulcer patients.

    abstract：OBJECTIVE:In healthy subjects a gastric meal at low pH inhibits gastric acid secretion, possibly by reducing gastrin release, whereas duodenal ulcer (DU) patients have been reported to show a lack of this low pH inhibition of gastric secretion. METHODS:The intragastric pH profiles were measured in seven healthy subjec...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365529509096321

    authors： Konturek JW,Konturek SJ,Domschke W

    更新日期：1995-08-01 00:00:00

  • Sources of the serum isoamylases and their normal range of variation with age.

    abstract：:The isoamylases in various human tissue homogenates and body fluids were separated by agarose gel electrophoresis. Nothing suggested any significant production of amylase in the liver. Minute amounts of amylase belonging to the pancreatic group of isoamylases might be produced by the glands of the proximal duodenum. T...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：

    authors： Skude G

    更新日期：1975-01-01 00:00:00

  • Effect of penicillamine and zinc on iron metabolism in Wilson's disease.

    abstract：OBJECTIVE:The physiology of iron metabolism in Wilson's disease is largely unknown, and there is a paucity of data on the real presence and progression of iron accumulation. The purpose of this study was to assess the iron metabolism parameters, including hepatic iron concentration, in follow-up liver biopsies and seru...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520701514495

    authors： Medici V,Di Leo V,Lamboglia F,Bowlus CL,Tseng SC,D'Incà R,Irato P,Burra P,Martines D,Sturniolo GC

    更新日期：2007-12-01 00:00:00

  • Pancreatic polypeptide secretion before and after gastric bypass surgery for morbid obesity.

    abstract：:Basal, meal-stimulated, and insulin-stimulated secretion of pancreatic polypeptide (PP) has been measured before and 3 and 12 months after gastric bypass surgery in 10 obese patients. The basal serum concentration of PP was significantly reduced after the operation. After a meal there was a significant increase in PP ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365528109181020

    authors： Schrumpf E,Linnestad P,Nygaard K,Giercksky KE,Fausa O

    更新日期：1981-01-01 00:00:00