Abstract:
AIM:To determine if ultra-low-dose (ULD) computed tomography (CT) utilising model-based iterative reconstruction (MBIR) with radiation equivalent to plain radiography allows the detection of lung nodules. MATERIALS AND METHODS:Ninety-nine individuals undergoing surveillance of solid pulmonary nodules undertook a low-dose (LD) and ULD CT during the same sitting. Image pairs were read blinded, in random order, and independently by two experienced thoracic radiologists. With LD-CT as the reference standard, the number, size, and location of nodules was compared, and inter-rater agreement was established. RESULTS:There was very good inter-rater agreement with regards nodules ≥4mm for both the LD- (k=0.931) and ULD-CT (k=0.869). One hundred and ninety-nine nodules were reported on the LD-CT by both radiologists and 196 reported on the ULD-CT, with no nodules reported only on the ULD-CT. This gives a sensitivity of 98.5% and specificity of 100% for ULD-CT with MBIR. The effective dose of radiation was significantly different between the two scans (p<0.0001), 1.67 mSv for the LD-CT and 0.13 mSv for the ULD-CT. CONCLUSION:ULD-CT utilising MBIR and delivering radiation equivalent to plain radiography, allows detection of lung nodules with high sensitivity. The attendant 10-fold reduction in radiation may allow for dramatic reductions in cumulative radiation exposure.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Miller AR,Jackson D,Hui C,Deshpande S,Kuo E,Hamilton GS,Lau KKdoi
10.1016/j.crad.2019.02.001subject
Has Abstractpub_date
2019-05-01 00:00:00pages
409.e17-409.e22issue
5eissn
0009-9260issn
1365-229Xpii
S0009-9260(19)30090-Xjournal_volume
74pub_type
杂志文章abstract::Either radionuclide or contrast venography, or both, were performed in nine patients 2 months to 4 years after insertion of Mobin-Uddin caval umbrella filter for prevention of recurrent pulmonary embolism. In six patients the cava was occluded, and three major groups of collaterals were observed (central, intermediate...
journal_title:Clinical radiology
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doi:10.1016/s0009-9260(82)80185-2
更新日期:1982-09-01 00:00:00
abstract::Three cases of carbon granuloma are described following the instillation of carbon solution at the time of stereotactic fine needle aspiration for pre-operative localization of impalpable mammographic abnormalities. If the carbon track is not excised following carbon instillation the retained carbon may result in a gr...
journal_title:Clinical radiology
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doi:10.1016/s0009-9260(98)80198-0
更新日期:1998-11-01 00:00:00
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journal_title:Clinical radiology
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doi:10.1016/s0009-9260(81)80338-8
更新日期:1981-11-01 00:00:00
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journal_title:Clinical radiology
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journal_title:Clinical radiology
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更新日期:2019-08-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a well recognized cause of an acute abdomen. What is less well recognized is that the underlying pathology can be varied. The computed tomography (CT) and ultrasound appearances of the gall-bladder in a case of SLE serositis are shown. The imaging findings were strongly suggestive...
journal_title:Clinical radiology
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doi:10.1016/s0009-9260(05)80670-1
更新日期:1991-12-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80082-0
更新日期:1992-05-01 00:00:00
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journal_title:Clinical radiology
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doi:10.1016/j.crad.2008.04.012
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journal_title:Clinical radiology
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doi:10.1016/j.crad.2015.02.017
更新日期:2015-07-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2008.11.001
更新日期:2009-06-01 00:00:00
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journal_title:Clinical radiology
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doi:10.1016/j.crad.2006.07.007
更新日期:2006-12-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2012.08.002
更新日期:2012-12-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2017.02.019
更新日期:2017-08-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.05.002
更新日期:2015-09-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.crad.2010.02.016
更新日期:2010-11-01 00:00:00
abstract::This study reviews prospectively a series of 29 patients who were examined by magnetic resonance imaging (MRI) and discography for degenerative disc disease. All had persistent low-back pain and non-diagnostic initial investigations, including plain films, myelography and/or computed tomography (CT). The imaging chara...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)82113-0
更新日期:1990-10-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(79)80072-0
更新日期:1979-05-01 00:00:00
abstract::Labelling leucocytes with 99Tcm using hexamethylpropyleneamine oxime (HMPAO) utilizes the advantages of technetium over indium in imaging inflammation. A retrospective study has been performed on 43 consecutive patients imaged with 99Tcm HMPAO labelled leucocytes in order to assess the reliability of the technique. Pa...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81933-6
更新日期:1990-09-01 00:00:00
abstract::The purpose of this article is to review the computed tomography (CT) and histopathological features of uncommon primary neoplasms of the thorax that can manifest clinically malignant features (multiplicity of pulmonary nodules, an invasive nature, and metastases or recurrence after surgery) with little evidence of hi...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2012.03.011
更新日期:2012-11-01 00:00:00
abstract::Thirty-six patients in whom peripheral cavernous haemangioma was clinically suspected were examined by 99mTc red blood cell scintigraphy. Twenty-five of these patients had a palpable lump, and they also underwent an ultrasound examination. Seven patients also had computed tomography and angiography was performed in on...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80224-7
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journal_title:Clinical radiology
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doi:10.1016/s0009-9260(97)80229-2
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80045-7
更新日期:1977-11-01 00:00:00
abstract::The aims and objectives of radiological teaching to clinical medical students at one teaching hospital are defined and the methods of achieving these using systematic small group tutorials are described. The objectives of the course are to enable a newly qualified doctor to request radiological investigations sensibly...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(84)80125-7
更新日期:1984-05-01 00:00:00
abstract::Transjugular intrahepatic portosystemic stent shunt (TIPSS) is a new percutaneous technique for reducing portal venous pressure. We attempted TIPSS in six patients with recurrent bleeding for oesophageal or gastric varices between July 1991 and January 1992 with success in five. There have been no deaths. One patient ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80438-6
更新日期:1992-09-01 00:00:00
abstract::The ultrasound features in eight cases of metastases to the thyroid are reported. The primary tumours were bronchogenic carcinoma (4 cases), breast carcinoma (2 cases), oesophageal carcinoma (1 case) and carcinoma of the stomach (1 case). In this series, none of the metastases were from malignant melanoma or a renal n...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81880-x
更新日期:1994-09-01 00:00:00
abstract:AIM:To determine the added value of dynamic contrast-enhanced imaging (DCE) over T2-weighted imaging (T2-WI) and diffusion-weighted imaging (DWI) for detection of clinically significant prostate cancer (csPC) in patients with elevated prostate-specific antigen (PSA). METHODS AND MATERIALS:Two hundred and forty-five pa...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2016.09.011
更新日期:2017-01-01 00:00:00
abstract:AIM:To compare the diagnostic performance of the 2017 (v2017) and 2018 versions (v2018) of the Liver Imaging-Reporting and Data System (LI-RADS) for hepatocellular carcinoma (HCC) using gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-MRI) and to evaluate the effect in v2018. MATERIALS AND METHODS:Treatment-...
journal_title:Clinical radiology
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doi:10.1016/j.crad.2019.11.004
更新日期:2020-04-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)82884-3
更新日期:1994-12-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81114-6
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abstract::In a prospective study, A mode ultrasound scanning contributed to the diagnosis and management of 24 of 50 consecutive patients with pleural disease. In 30% of patients it was superior to radiology in clarifying the solid or fluid nature of a pleural opacity, and in 42% of patients it allowed selection of the most app...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(81)80042-6
更新日期:1981-05-01 00:00:00