Abstract：
BACKGROUND:Permacol™ collagen paste, an acellular crosslinked porcine dermal collagen matrix suspension, is a new treatment option for anal fistula. Data remain limited, however, and as yet only the results of one case of Crohn's fistula treated with Permacol™ paste has been reported. The aim of this study was to assess the use of Permacol™ collagen paste in patients with cryptoglandular and Crohn's perianal fistulae. METHODS:A prospective study was conducted on patients with anal fistula, treated with Permacol™ paste. Patients were followed at 1 week, 6 and 12 months, and on demand thereafter. The main focus was on fistula healing and postoperative continence. The former was defined as the absence of signs of recurrence on clinical examination, proctoscopy and rigid rectoscopy. Fecal incontinence was assessed before surgery and at each follow-up. RESULTS:Thirty patients (19 women, 11 men; mean age 46 years), 12 (40%) of whom had Crohn's disease were included. The average number of previous fistula operations was 6. All patients had ≥ 6 months of follow-up, and 24 patients (80%) had ≥ 12 months of follow-up. The healing rate in all patients was 57% (17 of 30 patients) at 6 months and 63% (15 of 24 patients) at 12 months. One patient reported a worsening of fecal incontinence at 12 months; 2 patients had adverse events (perianal pain: n = 1, fluid accumulation n = 1) requiring fistula drainage. Patient characteristics, healing, incontinence, and adverse events did not differ significantly between patients with and without Crohn's disease. CONCLUSIONS:Our data indicate that Permacol™ paste is a safe and moderately effective treatment for cryptoglandular and Crohn's fistulae.
journal_name
Tech Coloproctoljournal_title
Techniques in coloproctologyauthors
Brunner M,Schneider I,Günther K,Grützmann R,Matzel KEdoi
10.1007/s10151-019-01932-zsubject
Has Abstractpub_date
2019-02-01 00:00:00pages
135-141issue
2eissn
1123-6337issn
1128-045Xpii
10.1007/s10151-019-01932-zjournal_volume
23pub_type
杂志文章abstract：BACKGROUND:Anastomotic leakage is still a major complication in colorectal surgery. Prompt recognition and immediate treatment of anastomotic leak during surgery may reduce postoperative morbidity and mortality. Various types of intraoperative anastomotic test have been proposed to reduce the incidence of this complica...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-012-0910-x
更新日期：2013-10-01 00:00:00
abstract：:Retained rectal foreign body is not an uncommon condition, but reliable epidemiological data are not available. The diagnosis and management can present a significant challenge due to delayed presentation and the reluctance of the patients to provide details of the incident. The aim of the clinical evaluation is to id...
journal_title：Techniques in coloproctology
pub_type： 杂志文章,评审
doi：10.1007/s10151-012-0899-1
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:A prospective randomized trial to assess the cleansing ability and tolerance of bowel preparations for colonoscopy was conducted in a group of 953 patients. METHODS:The bowel cleansing methods were: sennoside calcium, polyethylene glycol (PEG) lavage, oral sodium phosphate (NaP) in one 90-ml dose, oral NaP ...
journal_title：Techniques in coloproctology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s101510300003
更新日期：2003-04-01 00:00:00
abstract：:The aim of this study was to evaluate the role of ayurvedic setons in the treatment of low fistula-in-ano. One hundred and eight patients were randomised into either conventional fistulotomy (F) or ayurvedic cutting seton insertion (C). Endpoints investigated included time to wound healing and complications of surgery...
journal_title：Techniques in coloproctology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s101510100015
更新日期：2001-12-01 00:00:00
abstract：:Intussusception of the appendix is a rare condition. We present the case of a 72-year-old woman with multiple polyps in the colon with an appendix completely intussuscepted into a polyp within the caecum. The clinical features, preoperative diagnosis, classification and treatment of this condition are discussed with r...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-004-0068-2
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND:Technical factors affect oncologic outcomes in rectal cancer surgery. The anatomy of the bony pelvis can affect technical aspects of surgery, but is seldom considered preoperatively. We performed a morphometric analysis of the bony pelvis in patients having rectal cancer resection to assess its effect on sur...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-020-02273-y
更新日期：2020-10-01 00:00:00
abstract：:A 44-year-old man presented with a large and rapidly growing skin lesion approximately six months after resection of a rectal carcinoma. The lesion measured 40 cm in size, extended from the suprapubic area to the proximal half of the left groin, and showed a particular zosteriform aspect. Biopsy confirmed a metastatic...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-003-0019-3
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:The purposes of the study were the long-term evaluation of silicone implants with three-dimensional (3D) anal endosonography and its correlation with anal incontinence. METHODS:Fifteen patients were injected with silicone because of anal incontinence and co-existing internal anal sphincter disruption (n = 8...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-009-0502-6
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:We have been performing curative resection of colon cancer via a minilaparotomy without utilizing any laparoscopic instruments as an alternative to laparoscopic-assisted approach. Based on our experiences and improved surgical techniques, we have devised a new method for performing resection of stage 0/I col...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-010-0639-3
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:This study was designed to assess defecatory function in patients who underwent laparoscopic ventral rectopexy (LVR) for external rectal prolapse (ERP). METHODS:Thirty-one patients who underwent evacuation proctography 6 months postoperatively were assessed. Preoperative proctography had been performed in 2...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-015-1395-1
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Preoperative staging of rectal tumours is considered essential to tailoring treatment for individual patients. The aim of the present study was to evaluate the accuracy of 3-D-endorectal ultrasonography for the preoperative staging of rectal cancer. METHODS:Three hundred and fifty-seven patients with rectal...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-004-0099-8
更新日期：2004-11-01 00:00:00
abstract：:Haemorrhoidectomy is frequently associated with significant postoperative pain and prolonged hospital stay. New techniques to reduce these problems are constantly under evaluation. Amongst these, LigaSure haemorrhoidectomy is a safe and fast technique that fulfils the requirements of low-complication rate, fast wound ...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-009-0530-2
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Simple anal fistula is one of the most common causes of proctological surgery and fistulotomy is considered the gold standard. This procedure, however, may cause complications. The aim of this systematic review was to assess the surgical treatment of simple anal fistula with traditional and sphincter-sparing...
journal_title：Techniques in coloproctology
pub_type： 杂志文章,评审
doi：10.1007/s10151-020-02385-5
更新日期：2021-01-02 00:00:00
abstract：BACKGROUND:Total mesorectal excision (TME) has greatly reduced the local recurrence rate of rectal cancer after colorectal surgery. Transanal TME (TaTME) is potentially a suitable option for patients with mid and low rectal cancer. Robotic systems overcome the limitations of laparoscopic surgery. The aim of this study ...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-020-02337-z
更新日期：2020-09-21 00:00:00
abstract：BACKGROUND:There are different open healing and primary closure approaches for chronic pilonidal sinus (CPD) that differ in principles and extension. AIMS:To compare the results of different closure surgical techniques, we performed a meta-analysis of randomized controlled trials (RCT) comparing: (1) open wide excisio...
journal_title：Techniques in coloproctology
pub_type： 杂志文章,meta分析
doi：10.1007/s10151-014-1149-5
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Small bowel adenocarcinoma (SBA) remains a rare entity but occurs at increased frequency in the setting of chronic Crohn's disease (CD). Our aim was to study the presentation, diagnosis and prognosis of SBA in patients undergoing surgery for CD at a single institution. METHODS:We reviewed the medical record...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-020-02269-8
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Anal fissures can cause morbidity in an otherwise healthy young patient. The process of evacuation results in stretching and descent of the anoderm and perineum especially posteriorly. Posterior perineal support may provide counter pressure at the posterior aspect of the pelvic floor, balancing the pressure ...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-009-0453-y
更新日期：2009-03-01 00:00:00
abstract：:This technical note presents a variation of the stapled mucosal prolapsectomy for haemorrhoidal prolapse using the Lone Star Retractor. Our experience highlights the simplicity and usefulness of the technique which is based on the complete eversion of the prolapse carried out by the Lone Star Retractor, without using ...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/pl00012123
更新日期：2001-04-01 00:00:00
abstract：:Stapled hemorrhoidopexy is a widely used surgical technique for treating hemorrhoids, although severe complications have been reported. The authors report a rare case of extensive ascending intramural hematoma of the sigmoid colon complicating stapled hemorrhoidopexy, with perforation and hemoperitoneum. Diagnosis was...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-011-0696-2
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Transanal intersphincteric resection (ISR) was introduced and has been increasingly performed as an ultimate surgical treatment for extremely low rectal cancer. We considered that high quality and less invasive surgery could be achieved if ISR and laparoscopic surgery were combined. METHODS:Between December...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-006-0243-8
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:The use of biological materials for the repair of complex abdominal wall defects has increased over the years; however, the role of these materials in routine practice remains unclear. The aim of the study was to evaluate clinical outcomes following the use of Permacol™ porcine collagen surgical implant in c...
journal_title：Techniques in coloproctology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10151-015-1307-4
更新日期：2015-07-01 00:00:00
abstract：:Endoscopic polypectomy is the gold standard for the treatment of colorectal polyps. In the case of non-palpable lesions or to complete polyp removal, the lesions are located intra-operatively. With the advent of laparoscopy, identifying their position is even more important because there is no opportunity for intestin...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-004-0180-3
更新日期：2004-12-01 00:00:00
abstract：:Hereditary proctalgia is an extremely rare condition characterized by endosonographic evidence of internal anal sphincter (IAS) thickening and specific ultrastructural changes seen at light and electron microscopy (EM). We report the case of a 54-year-old Caribbean woman with severe proctalgia and IAS thickening, trea...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-007-0329-y
更新日期：2007-03-01 00:00:00
abstract：:Split transverse colostomy is a novel method of defunctioning the distal colon. Herein, we describe the method of this procedure and present early interim results showing that this procedure is safe, relatively complication free and feasible for many pathologies affecting the colon and pelvis, especially in alleviatio...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-006-0253-6
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:Pouchitis after total rectocolectomy is among the most common complications of patients with ulcerative colitis (UC). However, its frequency is quite rare in patients with familial adenomatous polyposis (FAP). We evaluated the inflammatory and pro-apoptotic activity in endoscopically normal mucosa of the ile...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-008-0395-9
更新日期：2008-03-01 00:00:00
abstract：INTRODUCTION:One in ten patients with rectal cancer presents with synchronous colorectal liver metastases. We present an up-to-date review of the different surgical strategies available for rectal cancer patients with synchronous colorectal liver metastases. METHOD:A literature review of MEDLINE, Cochrane and Google s...
journal_title：Techniques in coloproctology
pub_type： 杂志文章,评审
doi：10.1007/s10151-012-0888-4
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:Fibre is often recommended as the first-choice treatment but its effects can be uneven. The aim of the study was to compare the clinical efficacy and tolerability of fibre versus lactulose in outpatients with chronic constipation. METHODS:In a prospective randomized crossover trial, patients were randomized...
journal_title：Techniques in coloproctology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10151-006-0262-5
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:Early detection of colorectal anastomotic leakage (AL) may lead to better outcome. AL may be preceded by change in local metabolism and local ischaemia. Microdialysis of the peritoneal cavity is able to measure these changes in real-time and is minimally invasive. The aim of this prospective cohort study was...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-013-1020-0
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:The differences between the costs of robotic rectal resection and of the laparoscopic approach are still not well known. The aim of this study was to evaluate the cost-effectiveness of robotic versus laparoscopic surgery. METHODS:We conducted an observational, comparative, prospective, non-randomized study ...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-020-02151-7
更新日期：2020-03-01 00:00:00
abstract：:Laparoscopic colectomy for cancer is increasingly practiced worldwide in the last 2 decades. However, due to procedural complexity, laparoscopic rectal cancer excision had not proceeded at a similar pace. This article deals with the technique of laparoscopic anterior resection. Resection of rectosigmoid or upper recta...
journal_title：Techniques in coloproctology
pub_type： 杂志文章
doi：10.1007/s10151-009-0557-4
更新日期：2010-03-01 00:00:00
