Abstract:
OBJECTIVES:The primary objectives were to evaluate the quality of development and reporting of American Academy of Pediatrics (AAP) guidelines and to determine the level of evidence underlying the recommendations. METHODS:Two reviewers scored each guideline by using the Appraisal of Guidelines for Research and Evaluation II (AGREE-II) instrument and determined the level of evidence for each recommendation in each guideline. Subgroup analyses compared AAP guidelines published before and after key changes in AAP guideline development policy and compared internal with endorsed guidelines. RESULTS:For the 28 current guidelines, the highest average scores on AGREE-II were in scope and purpose (75%) and clarity of presentation (73%). The lowest average scores were in editorial independence (17%) and applicability (30%). The only domain that improved after AAP policy updates was editorial independence (P = .01). Of the 190 treatment recommendations, 43% were based on experimental studies, 30% on observational studies, and 27% on expert opinion or no reference. Compared with early guidelines, late guidelines included a higher proportion of treatment recommendations based on experimental studies (P = .05). CONCLUSIONS:There was no clear improvement in the quality of development and reporting of AAP clinical practice guidelines over time. Routine application of AGREE-II to guideline development could enhance guideline quality. The proportion of guideline recommendations based on experimental evidence has increased slightly over time. Pediatric research agendas should be matched to vital gaps in the evidence underlying pediatric guidelines.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Isaac A,Saginur M,Hartling L,Robinson JLdoi
10.1542/peds.2012-2027subject
Has Abstractpub_date
2013-04-01 00:00:00pages
732-8issue
4eissn
0031-4005issn
1098-4275pii
peds.2012-2027journal_volume
131pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVES:To assess the annual prevalence of physical violence from dating partners among a representative sample of sexually experienced adolescent girls attending US public and private high schools, as well as sexual risk behaviors and pregnancy among this population. DESIGN, SETTING, PARTICIPANTS, AND MEASURES:Fem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.114.2.e220
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:To identify possible causes of suboptimal glycemic control (ascertained by hemoglobin A1c [HbA1c] level) in youths using insulin pump therapy. METHODS:Forty-eight youths who were receiving insulin pump therapy for > or =6 months, and who were using insulin pumps and blood glucose meters with data that could ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.113.3.e221
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Studies have indicated that internationally adopted children have an increased risk of developing precocious puberty, but no epidemiologic risk estimates have previously been calculated. We aimed to assess the risk of developing precocious puberty in intercountry adoptees, children immigrating with their fam...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2939
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Sexual assault is a major cause of injury, unplanned pregnancy, HIV infection, and mental health problems worldwide. In parts of sub-Saharan Africa, sexual assault has reached epidemic proportions. This study evaluated the efficacy of an empowerment and self-defense intervention for adolescent ...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2013-3414
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To examine the impact of a mentoring and skills group intervention for preadolescent children in foster care on placement stability and permanence at 1-year postintervention. METHODS:A randomized controlled trial was conducted with 9- to 11-year-old children who were maltreated and placed in foster care (n =...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2011-3447
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:The current recommendation for choosing an appropriate size cuff for measuring blood pressure (BP) is a bladder width to equal 40% of the upper arm circumference (UAC). However, most physicians use the older two-thirds or three-fourths upper arm length (UAL) recommendations to choose a cuff. The aim of this s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.110.5.920
更新日期:2002-11-01 00:00:00
abstract::Ventricular arrhythmia in the perinatal period is observed with greater frequency than reported in the literature. Four cases from the authors' experience and an analysis of the literature are presented. Of the total of 45 cases, nine were detected in utero, three persisted beyond the neonatal period, and two resulted...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract:OBJECTIVES:To investigate associations between timing of adiposity rebound (AR; the period in childhood where BMI begins to increase from its nadir) and adiposity (BMI, fat mass) at age 15 years in the Avon Longitudinal Study of Parents and Children (ALSPAC). METHODS:The sample consisted of 546 children with AR derive...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2014-1908
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To review systematically and to summarize the existing literature regarding performance of rapid diagnostic tests for urinary tract infection (UTI) in children. DESIGN:Systematic review and meta-analysis. METHODS:Published articles reporting the performance of urine dipstick tests (leukocyte esterase [LE] a...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析
doi:10.1542/peds.104.5.e54
更新日期:1999-11-01 00:00:00
abstract::The hypothesis that the parents and siblings of children with nephrotic syndrome are more likely to develop psychosocial problems than those of healthy children was tested. Seventy-nine siblings from 36 such families were compared with 79 healthy children from closely matched families using interviews, parent rating s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:To assess patterns of morbidity and associated factors in late infancy and early childhood among human immunodeficiency virus (HIV)-infected and -uninfected African children. DESIGN:Prospective study. SETTING:The Queen Elizabeth Central Hospital, Blantyre, Malawi. PARTICIPANTS:Children with known HIV statu...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.6.e77
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVES:Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) frequently co-occur. Understanding the endophenotype of children with both ASD and ADHD may impact clinical management. In this study, we compare the comorbidity of anxiety and mood disorders in children with ASD, with and wit...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1377
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:Digital technologies offer new platforms for health promotion and disease management. Few studies have evaluated the use of digital technology among families receiving care in an urban pediatric primary care setting. METHODS:A self-administered survey was given to a convenience sample of caregivers bringing ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0594
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVES:The Hawaii Child Asthma Research to Elevate Standards (CARES) Program implemented an emergency department (ED)-based education and management program to facilitate National Asthma Education and Prevention Program (NAEPP) guideline understanding among asthmatic children and their families, ED staff, and healt...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2005-2000L
更新日期:2006-04-01 00:00:00
abstract::The clinical course, laboratory data, outcome, and autopsy findings in 61 pediatric patients with suspected brain death were reviewed. In 58% of patients, the initial EEG was isoelectric, and cerebral blood flow was absent. In six of nine children, the initial EEG, which showed activity, became isoelectric by 72 hours...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVES:Postnatal survival rates of very low birth weight (VLBW) infants are well established for each birth weight or gestational age category. These figures do not differentiate viable infants who survive the first few days of life from extremely immature ones who die shortly after birth. This study aimed to devel...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-2810
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:To determine if race/ethnicity-based differences exist in the management of pediatric abdominal pain in emergency departments (EDs). METHODS:Secondary analysis of data from the 2006-2009 National Hospital Ambulatory Medical Care Survey regarding 2298 visits by patients ≤ 21 years old who presented to EDs wit...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-3127
更新日期:2013-10-01 00:00:00
abstract::Population-based data on varicella complications are presented using information both from national sample surveys of hospitalizations and physician office visits and from reviews of medical records for all cases occurring within one community (Olmsted County, Minnesota) during a specified period. Acute cerebellar ata...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1986-10-01 00:00:00
abstract::Electronic health records (EHRs) facilitate several innovations capable of reforming health care. Despite their promise, many currently unanswered legal, ethical, and financial questions threaten the widespread adoption and use of EHRs. Key legal dilemmas that must be addressed in the near-term pertain to the extent o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-2184
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:The goal was to determine the impact of a community-wide educational intervention on parental misconceptions likely contributing to pediatric antibiotic overprescribing. METHODS:We conducted a cluster-randomized trial of a 3-year, community-wide, educational intervention directed at parents of children < 6 y...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2006-2600
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Latino-white disparities in age at autism spectrum disorder (ASD) diagnosis may be modified by primary care pediatrician (PCP) practices and beliefs. The objectives of this study were to assess ASD and developmental screening practices, attitudes toward ASD identification in Latino children, a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0383
更新日期:2013-09-01 00:00:00
abstract::The opportunity to improve health care using existing scientific knowledge is immense. Much is known that is not being used in routine care, leading to a large gap between knowledge and practice. Collaborative improvement models bring health care professionals together to focus on this gap and to accelerate the pace o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Acute acetaminophen intoxication was studied in the dog to characterize pathogenesis and in the mouse as a model for antidotal research. In the dog, overt toxicity was manifested principally by cyanosis, facial and paw edema, gastrointestinal disturbance, and coma. Typical laboratory findings were methemoglobinemia, h...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-11-01 00:00:00
abstract:OBJECTIVE:To examine individual changes in energy expenditure and physical activity during prepubertal growth in boys and girls. METHODS:Total energy expenditure (TEE), resting energy expenditure, physical activity-related energy expenditure, reported physical activity, and fat and fat-free mass were measured three ti...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.101.5.887
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVES:With this study we aimed to compare survival rates for children with Down syndrome in 2 time periods, 1 before prenatal screening (1988-1990) and 1 contemporaneous with screening (1998-2000), and to examine the frequency of comorbidities and their influence on survival rates. METHODS:Record-linkage was perf...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-2840
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:Our goal was to test the effect of prenatal and infancy home visits by nurses on mothers' fertility and children's functioning 7 years after the program ended at child age 2. METHODS:We conducted a randomized, controlled trial in a public system of obstetric and pediatric care. A total of 743 primarily black...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2006-2111
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Diagnostic imaging is often used in the evaluation of children with possible appendicitis. The utility of imaging may vary according to a patient's age and gender. The objectives of this study were (1) to examine the use of computed tomography (CT) and ultrasound for age and gender subgroups o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-3375
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Neurosarcoid is seldom recognized in children. In the absence of any large pediatric series, it has been assumed that the presenting signs and symptoms are identical in adults and children. OBJECTIVE:To test the hypothesis that childhood neurosarcoid differs in presenting signs and symptoms from neurosarcoi...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.112.6.e480
更新日期:2003-12-01 00:00:00
abstract::A 5-year-old boy with chronic granulomatous disease (CGD) received four granulocyte transfusions from unrelated HLA-matched donors as part of therapy for a hepatic abscess. Survival studies of transfused granulocytes using the endotoxin-stimulated nitroblue tetrazolium (NBT) test on two occasions demonstrated 19.6% an...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::We report here the case of an infant who developed life-threatening rigid-chest syndrome after receiving an accidental overdose of methadone. The child responded to narcotic reversal. Pediatric physicians should be aware of this possible complication. ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-3243
更新日期:2010-07-01 00:00:00