Abstract：
:Understanding of the interaction between human MG63 osteoblast-like cells and surfaces is necessary in the field of tissue engineering and biomaterials. Various titanium surfaces are widely used as not only implant materials, but also as miniscrews in orthodontics. Our goal was to assess the proteomic response of MG63 osteoblast-like cells to different titanium surfaces. MG63 osteoblast-like cells were cultured on three different titanium surfaces: a smooth surface (S), a sandblasted with large grit and acid-etched surface (SLA), and a surface coated with a thin layer of hydroxyapatite (HA). Cells grown on the rougher surfaces (SLA and HA) exhibited downregulated cell proliferation and morphological changes. In the proteomic analysis, cells grown on the SLA surface showed upregulated expression of protocadherin-β3 precursor, kinase insert domain receptor, fibroblast growth factor receptor-3, and insulin-like growth factor I, while the expression levels of cell adhesion kinase, collagen α-1(I) chain precursor, collagen type XI α2, and cadherin-11 were upregulated in cells grown on the HA surface. These proteins are known to be involved in osteoblast adhesion, growth, and differentiation. Thus, the surface properties of dental materials can influence the expression of proteins involved in osseointegration-related processes. Proteomic analysis may reveal changes in novel proteins that explain why osseointegration varies depending on surface properties.
journal_name
Odontologyjournal_title
Odontologyauthors
Kim CS,Lee KJ,Kim JE,Park YG,Ryu JJ,Kim HRdoi
10.1007/s10266-013-0115-4subject
Has Abstractpub_date
2014-07-01 00:00:00pages
241-8issue
2eissn
1618-1247issn
1618-1255journal_volume
102pub_type
杂志文章相关文献
Odontology文献大全abstract：:Periodontal ligament is considered a rich source of mesenchymal stem cells for pulp regeneration. This study investigated the effect of iloprost, a prostacyclin analog, on cell proliferation and the expression of angiogenesis-related genes in human periodontal ligament cells (hPDLs) in vitro. The hPDLs were treated wi...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-017-0307-4
更新日期：2018-01-01 00:00:00
abstract：:Chemerin is a chemoattractant protein that directs inflammatory cells that express its receptor chemokine receptor-like 1 (ChemR23) towards sites of inflammation. C-C chemokine receptor-like 2 (CCRL2), is the other receptor of chemerin, improves the interaction between chemerin and ChemR23. The aim of this study was t...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-017-0297-2
更新日期：2018-01-01 00:00:00
abstract：:The aim of this study was to investigate margin integrity of Class V composite restorations in demineralized and sound enamel after bonding with different etch-and-rinse and self-etch adhesive systems. Out of a total of 60 specimens from bovine incisors, 30 specimens were demineralized (21 days, acid buffer, pH 4.95) ...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-018-0398-6
更新日期：2019-07-01 00:00:00
abstract：:We examined the expression of keratin 18 (K18), by immunofluorescence staining, while monitoring morphological changes in the periderm on the lingual epithelium of rats by laser-scanning microscopy of epoxy resin-embedded, semi-ultrathin sections. We also examined differential interference contrast (DIC) images of the...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-005-0059-4
更新日期：2006-09-01 00:00:00
abstract：:The goal of this short communication is to present finite element analysis comparison of the stress distribution between CAD/CAM full crowns made of Lava Ultimate and of IPS e.max CAD, adhesively luted to natural teeth and to implant abutments with the shape of natural teeth. Six 3D models were prepared using a 3D con...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-016-0276-z
更新日期：2017-04-01 00:00:00
abstract：:Infective endocarditis is frequently attributed to oral streptococci. Although the pathogenetic mechanisms are not well understood, interaction between streptococci and phagocytes is thought to be important for infective endocarditis. In this study, HL-60 cell-derived monocytes were characterized following interaction...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-011-0044-z
更新日期：2012-07-01 00:00:00
abstract：:Basic activities of daily living (ADL) is a critical indicator of independency in older adults. The purpose of this study is to evaluate impact of ADL decline on coughing ability, as determined by peak expiratory flow rate (PEFR), and to evaluate impact of ADL decline on the ability of tongue cleaning intervention to ...
journal_title：Odontology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10266-019-00415-9
更新日期：2019-07-01 00:00:00
abstract：:Streptococcus gordonii, a bacterium involved in the initial colonization of tooth surfaces, contributes to dental biofilm formation and is an important cause of infective endocarditis. This study aimed to investigate the influence of surface reaction-type pre-reacted glass ionomer (S-PRG) filler on oral bacterial grow...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-015-0217-2
更新日期：2016-09-01 00:00:00
abstract：:There exists a close connection between changes occurring in the teeth and those occurring in the jaw during the evolutionary process. In mammals, the roots of teeth are supported, along with periodontal ligaments and alveolar bones by a unique structure termed the gomphosis. In the present study, we performed combine...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-020-00489-w
更新日期：2020-07-01 00:00:00
abstract：:In the original publication of the article, one of the author names was published incorrectly as José L. Calvo. The correct name is José L. Calvo-Guirado. ...
journal_title：Odontology
pub_type： 已发布勘误
doi：10.1007/s10266-018-0357-2
更新日期：2019-04-01 00:00:00
abstract：:This study investigated the prevalence and distribution of anomalies of permanent dentition in the current Japanese population by examining an unbiased sample. We conducted a survey of dental anomalies by mass dental screening at eight high schools in 2012. Participants were all students with permanent dentition. Dent...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-015-0225-2
更新日期：2016-09-01 00:00:00
abstract：:Acemannan has been previously reported as a direct pulp-capping agent in animal study. This natural material demonstrated its biocompatibility and enhanced reparative dentin formation. The objective of this study was to investigate the action of acemannan as a direct pulp-capping material in human primary teeth with d...
journal_title：Odontology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10266-015-0215-4
更新日期：2016-09-01 00:00:00
abstract：:The propofol dose requirement and the emergence time are affected by antiepileptic use. The effects on anesthesia of the number and kind of antiepileptic agents have not been reported. We investigated the relationship between the kind and number of antiepileptic agents and the propofol dose requirement for anesthesia ...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-019-00457-z
更新日期：2020-01-01 00:00:00
abstract：:Orthognathic surgery is sometimes performed for fibrous dysplasia to correct malocclusion or facial asymmetry. However, Le Fort 1 osteotomy for this disease is difficult because of severe anatomical abnormality. Computer-assisted surgery is a rapidly developing technique in oral and maxillofacial surgery that is helpi...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-010-0124-5
更新日期：2010-07-01 00:00:00
abstract：:Several growth factors and their receptors, such as epidermal growth factor receptor, have been studied as prognostic biomarkers for many epithelial malignancies. The signal transduction cascade of those receptors includes RAS/RAF/ERK, PI3K/Akt/mTOR, and STAT3 pathways. The aim of this study was to investigate the exp...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-019-00428-4
更新日期：2020-01-01 00:00:00
abstract：:The aim of this study was to investigate and compare, via finite element analysis (FEA), the effects of endodontic access and canal preparation on stress distribution under functional loading of a mandibular molar treated with novel (TRUShape) and conventional (Vortex) rotary root canal preparation instruments. Identi...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-016-0232-y
更新日期：2017-01-01 00:00:00
abstract：:The purpose of this noninferiority trial was to compare postoperative pain relief after one-visit root canal therapy (ORCT) with a pulpotomy performed with a new endodontic calcium-enriched mixture cement (PCEM) in human permanent molars with irreversible pulpitis. A total of 407 selected patients were randomly alloca...
journal_title：Odontology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s10266-010-0127-2
更新日期：2010-07-01 00:00:00
abstract：:We aimed at comparing the performance of vacuum-formed thermoplastic retainers (VFR) worn either full-time or part-time, in maintaining orthodontic treatment results in terms of tooth alignment, arch form and occlusion. We reviewed randomized and prospective controlled clinical trials comparing VFR wearing protocols a...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-016-0254-5
更新日期：2017-04-01 00:00:00
abstract：:Irradiation of the salivary glands results in the generation of free radicals from metal ions present in the secretory granules of acinar cells, a process that is believed to exacerbate radiation damage to the salivary glands. We therefore conducted a comparative investigation of radiation damage to the acinar cells o...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-004-0032-7
更新日期：2004-09-01 00:00:00
abstract：:In order to clarify the influence of epinephrine in local anesthetics on endogenous epinephrine, we examined the concentration of plasma catecholamines (epinephrine and norepinephrine) and hemodynamics by administering 4 ml of 2% lidocaine containing different concentrations of epinephrine. Forty-three healthy adult m...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-005-0044-y
更新日期：2005-09-01 00:00:00
abstract：:The aim of this paper was to demonstrate the treatment outcomes following immediate functional loading concept of short implants inserted for single tooth replacement in the posterior maxilla. The study was performed on 63 patients who received short (6 mm) implants for single tooth replacement in the posterior maxill...
journal_title：Odontology
pub_type： 临床试验,杂志文章
doi：10.1007/s10266-018-0378-x
更新日期：2019-04-01 00:00:00
abstract：:The response of bone cells to mechanical loading is mediated by the cytoskeleton. Since the bone anabolic agent fluoride disrupts the cytoskeleton, we investigated whether fluoride affects the response of bone cells to mechanical loading, and whether this is cytoskeleton mediated. The mechano-response of osteoblasts w...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-011-0013-6
更新日期：2011-07-01 00:00:00
abstract：:The most studied medical condition related with dental erosions is gastroesophageal reflux disease (GERD). The aim of this study was to assess other predictors of dental erosions besides GERD in outpatients referred for upper digestive endoscopy. In a cross-sectional study, we prospectively evaluated 235 patients who ...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-020-00505-z
更新日期：2020-10-01 00:00:00
abstract：:Over the past decade, remarkable progress has been made in the study of molecular mechanisms involved in degenerative temporomandibular joint arthritides. Based on recent findings, models of degenerative temporomandibular joint disease predict that mechanical loads trigger a cascade of molecular events leading to dise...
journal_title：Odontology
pub_type： 杂志文章,评审
doi：10.1007/s10266-005-0056-7
更新日期：2005-09-01 00:00:00
abstract：:The aim of this study was to evaluate the bleaching effectiveness and mineral alterations following the use of experimental bleaching gels that included 6% hydrogen peroxide (HP), titanium dioxide (TiO2) and/or chitosan in comparison with the routinely used 35% HP bleaching gel. Thirty-six maxillary anterior teeth wer...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-020-00526-8
更新日期：2021-01-01 00:00:00
abstract：:The aim of this study is to evaluate through computed tomography differences in cortical plate thickness of condyle in patients with a different facial vertical skeletal pattern. The final sample of this retrospective study included CBCT exams of 60 adult subjects (mean age 33.2 ± 5.6), selected from the digital archi...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-020-00510-2
更新日期：2020-10-01 00:00:00
abstract：:In the parotid glands (PGs) of intact male mice (12 weeks of age, ICR strain), immunofluorescence labels for a true tissue kallikrein, mK1, and for nerve growth factor (NGF) were recognized through the subluminal edges of the striated duct (SD) segments and interlobular duct segments. Because of their small size, secr...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-008-0090-3
更新日期：2009-01-01 00:00:00
abstract：:The aim of the study was to investigate any correlation between tactile sensation and occlusal loading conditions of mandibular premolars and molars, by means of tactile detection threshold (TDT). TDTs of mandibular premolars and molars of twenty adults were determined by calibrated monofilaments. Occlusal force (OF) ...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-011-0007-4
更新日期：2011-07-01 00:00:00
abstract：:To compare the 1-year clinical performance of lithium disilicate and resin composite CAD/CAM onlay restorations. Twenty patients that required two restorations in posterior teeth, with at least one cusp to be covered, received two onlays. One was made with IPS e.max CAD (Ivoclar-Vivadent) and the other with Lava Ultim...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-020-00539-3
更新日期：2021-01-01 00:00:00
abstract：:The purposes of this study were to establish normative data for mesiodistal tooth crown diameters and arch dimensions in Mongolian adults and to compare them with those of Japanese adults. The study materials comprised dental casts of 100 modern Mongolian and 100 Japanese subjects (50 males, 50 females for each) with ...
journal_title：Odontology
pub_type： 杂志文章
doi：10.1007/s10266-013-0130-5
更新日期：2014-07-01 00:00:00
