Transcatheter left atrial appendage occlusion.

Abstract:

:Occlusion of the left atrial appendage (LAA) may reduce the risk of stroke in patients with atrial fibrillation (AF). Trials comparing LAA occlusion to warfarin anticoagulation in patients with nonvalvular AF showed a reduction in hemorrhagic stroke, although an increase in safety events due to procedural complications. Long-term follow-up suggests possible superiority of LAA occlusion due to fewer strokes and bleeding events. The superior dosing and safety profiles of the novel oral anticoagulants raise the accepted threshold for safety and efficacy of LAA occlusion procedures, and underscore the need for randomized studies comparing LAA occlusion with these newer anticoagulants.

journal_name

Cardiol Clin

journal_title

Cardiology clinics

authors

Don CW,Fuller CJ,Reisman M

doi

10.1016/j.ccl.2013.05.008

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

363-84

issue

3

eissn

0733-8651

issn

1558-2264

pii

S0733-8651(13)00036-2

journal_volume

31

pub_type

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