YouTube English videos as a source of information on breast self-examination.

abstract：PURPOSE:The main objectives of this study were to identify risk factors for local in-breast tumor recurrence after breast-conservation and to evaluate the impact of IBTR (in-breast tumor recurrence) on overall survival. METHODS:A total of 335 consecutive patients with 346 invasive and in situ breast cancers were treat...

journal_title：Breast cancer research and treatment

authors： Mechera R,Viehl CT,Oertli D

更新日期：2009-07-01 00:00:00

abstract：:Tumour hypoxia, being widespread in solid tumours, is related to an increased risk of invasion and metastasis as well as to resistance to chemotherapy and radiotherapy. Hypoxia-inducible factor-1alpha (HIF-1alpha) has emerged as the key regulator of the cellular response to hypoxia. In primary breast cancers, HIF-1alp...

journal_title：Breast cancer research and treatment

authors： Smollich M,Götte M,Kersting C,Fischgräbe J,Kiesel L,Wülfing P

更新日期：2008-03-01 00:00:00

abstract：:We compared levels of erbB-2 oncoprotein among three groups: Group I included 60 asymptomatic women; Group II had 51 women with benign breast biopsies; and Group III had 67 women with node-negative breast cancer. Serological levels of erbB-2 protein were measured in all participants; tumor levels were measured for Gro...

journal_title：Breast cancer research and treatment

authors： Breuer B,Smith S,Thor A,Edgerton S,Osborne MP,Minick R,Cody HS 3rd,Nowak E,Cortese A,Simmons RM,Carney WP,Brandt-Rauf PW

更新日期：1998-06-01 00:00:00

abstract：:Preclinical and epidemiologic evidence supports a possible role for beta-adrenergic blocking drugs (beta-blockers), and angiotensin-converting enzyme inhibitors (ACEIs) in promoting survival after breast cancer. However, these drugs are often used concurrently with aspirin, and there is a growing body of evidence indi...

journal_title：Breast cancer research and treatment

authors： Holmes MD,Hankinson SE,Feskanich D,Chen WY

更新日期：2013-06-01 00:00:00

abstract：:The epidermal growth factor (EGF) is one of several growth factors involved in normal breast epithelial development and tumor proliferation. EGF and EGF-like peptide TGF alpha bind and activate the same membrane receptor protein. This receptor (EGF-R) has been recently studied in breast tumor biopsies and its detectab...

journal_title：Breast cancer research and treatment

authors： Falette N,Lefebvre MF,Meggouh F,Eynard M,Garin E,Saez S

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:Based on available phase III trial data, we performed a cost-effectiveness analysis of different treatment strategies that can be used in patients with newly diagnosed HER2-positive metastatic breast cancer (mBC). PATIENTS AND METHODS:We constructed a Markov model to assess the cost-effectiveness of four diffe...

journal_title：Breast cancer research and treatment

authors： Diaby V,Adunlin G,Ali AA,Zeichner SB,de Lima Lopes G,Kohn CG,Montero AJ

更新日期：2016-11-01 00:00:00

abstract：AIMS:Rapamycin and its analogues are currently being tested in clinical trials as novel-targeted anticancer agents. Pre-clinical studies that used breast cancer cell lines have suggested that p-Akt or p-S6K1 expressing tumors, as well as PTEN negative tumors, were sensitive to rapamycin. The aims of this study were to ...

journal_title：Breast cancer research and treatment

authors： Noh WC,Kim YH,Kim MS,Koh JS,Kim HA,Moon NM,Paik NS

更新日期：2008-08-01 00:00:00

abstract：:Previously we have shown that exercising rats prior to administration of 50 mg NMU/kg (high dose) significantly decreased tumor multiplicity, but not incidence or latency. We hypothesized that the dose of NMU saturated the system such that the exercise intervention was overshadowed. Therefore, the purpose of this inve...

journal_title：Breast cancer research and treatment

authors： Whittal-Strange KS,Chadan S,Parkhouse WS

更新日期：1998-01-01 00:00:00

abstract：:Germline mutations in the BRCA1/2 genes account for the majority of hereditary breast ovarian cancer (HBOC). Identification of causal mutations may have significant impact on clinical management of such families. Despite high mutation detection rate, many HBOC cases remain without identified cause. These cases warrant...

journal_title：Breast cancer research and treatment

authors： Konecny M,Milly M,Zavodna K,Weismanova E,Gregorova J,Mlkva I,Ilencikova D,Kausitz J,Bartosova Z

更新日期：2011-02-01 00:00:00

abstract：:The positive effects of tamoxifen (TAM) on breast cancer recurrence and survival as well as on overall mortality have led to its use as the predominant adjuvant therapy among women with breast cancer. However, the association of TAM intake with undesirable side effects has been reported in numerous studies. This analy...

journal_title：Breast cancer research and treatment

authors： Gallicchio L,Lord G,Tkaczuk K,Danton M,Lewis LM,Lim CK,Flaws JA

更新日期：2004-05-01 00:00:00

abstract：:Recent compelling evidence indicates that mutation, aberrant expression, and dysregulation of microRNA (miRNA) biogenesis are implicated in cancer development and progression. Based on the important role of miRNA biogenesis pathway in carcinogenesis, we hypothesized that genetic variations in this pathway genes may pl...

journal_title：Breast cancer research and treatment

authors： Sung H,Lee KM,Choi JY,Han S,Lee JY,Li L,Park SK,Yoo KY,Noh DY,Ahn SH,Kang D

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To explore the ability of intraoperative specimen radiography (SR) to correctly identify positive margins in patients receiving breast conserving surgery (BCS). To assess whether the reoperation rate can be reduced by using this method. METHODS:This retrospective study included 470 consecutive cases receiving ...

journal_title：Breast cancer research and treatment

authors： Funk A,Heil J,Harcos A,Gomez C,Stieber A,Junkermann H,Hennigs A,Rauch G,Sinn HP,Riedel F,Schäfgen B,Hug S,Maier A,Blumenstein M,Domschke C,Schott S,Wallwiener M,Rom J,Schütz F,Sohn C,Golatta M

更新日期：2020-01-01 00:00:00

abstract：:The aim of this study is to evaluate the impact of CYP2D6 genotyping in predicting disease-free survival and toxicity in breast cancer patients treated with adjuvant tamoxifen. DNA from 91 patients was genotyped using the AmpliChip CYP450 GeneChip, Roche that facilitates the classification of individuals by testing 27...

journal_title：Breast cancer research and treatment

authors： Ramón y Cajal T,Altés A,Paré L,del Rio E,Alonso C,Barnadas A,Baiget M

更新日期：2010-01-01 00:00:00

abstract：:We have compared by RNA in situ hybridisation on serial cryo-sections the distribution of cathepsin D (cathD), stromelysin 3 (strom-3), and urokinase plasminogen activator (UPA) gene expression in different tissues of human benign and malignant mammary tumors. Cath-D expression was found to be higher in adenocarcinoma...

journal_title：Breast cancer research and treatment

authors： Escot C,Zhao Y,Puech C,Rochefort H

更新日期：1996-01-01 00:00:00

abstract：:Breast reduction is a common surgical procedure performed by plastic and oncoplastic breast surgeons. The authors report on the incidence and management of cancer and atypical hyperplasia in breast reduction specimens from one institution over a 10-year period. All patients who underwent breast reduction surgery at No...

journal_title：Breast cancer research and treatment

authors： Goyal A,Coulson SG,Wu JM,Suvarna SK,Reed MW,Caddy CM

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:Breast cancer is a leading cause of cancer deaths in women, but despite steady improvements in therapies, treatment is still suboptimal. Immunotherapy holds promise as a more effective therapy for breast cancer; supporting this, our prior study showed that patients possessing HER2-reactive CD8+ T cells in blood...

journal_title：Breast cancer research and treatment

authors： Janssen N,Fortis SP,Speigl L,Haritos C,Sotiriadou NN,Sofopoulos M,Arnogiannaki N,Stavropoulos-Giokas C,Dinou A,Perez S,Pawelec G,Baxevanis CN,Shipp C

更新日期：2017-01-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) regulate diverse cellular processes, such as proliferation, differentiation, and apoptosis. The BMPs have been studied in several cancers, but thus far contradictory results have been obtained and, especially in breast cancer, information on BMPs is still limited. We performed a syst...

journal_title：Breast cancer research and treatment

authors： Alarmo EL,Kuukasjärvi T,Karhu R,Kallioniemi A

更新日期：2007-06-01 00:00:00

abstract：:Poly(ADP-ribose) polymerase-1 (PARP1) is a key facilitator of DNA repair. PARP inhibitors have gained recent attention as promising therapeutic agents for the treatment of solid tumours including breast cancer (BC). However, the biological and clinical significance of PARP1 expression in BC and its role in DNA-damage ...

journal_title：Breast cancer research and treatment

authors： Green AR,Caracappa D,Benhasouna AA,Alshareeda A,Nolan CC,Macmillan RD,Madhusudan S,Ellis IO,Rakha EA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Adjuvant therapy decisions may be partly based on the results of a multigene quantitative reverse transcription-polymerase chain reaction (RT-PCR)-based assay: the 21-gene recurrence score (RS) test of resection specimens. When necessary, core needle biopsy (CNB) may be considered as a surrogate. Here, we ev...

journal_title：Breast cancer research and treatment

authors： Qi P,Yang Y,Bai QM,Xue T,Ren M,Yao QL,Yang WT,Zhou XY

更新日期：2021-01-13 00:00:00

abstract：PURPOSE:Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer and associated with early metastasis, drug resistance, and poor patient survival. Fork head box M1 (FOXM1) is considered as an emerging molecular target due to its oncogenic role and high overexpression profile in 85% in TNBC. However, ...

journal_title：Breast cancer research and treatment

authors： Hamurcu Z,Kahraman N,Ashour A,Ozpolat B

更新日期：2017-06-01 00:00:00

abstract：:BRCAness breast tumors represent a group of sporadic tumors characterized by a reduction in BRCA1 gene expression. As BRCA1 is involved in double-strand breaks (DSBs) repair, dysfunctional BRCA pathway could make a tumor sensitive to DNA damaging drugs (e.g., platinum agents). Thus, accurately identifying BRCAness cou...

journal_title：Breast cancer research and treatment

authors： Branham MT,Campoy E,Laurito S,Branham R,Urrutia G,Orozco J,Gago F,Urrutia R,Roqué M

更新日期：2016-01-01 00:00:00

abstract：:The mechanism by which transforming growth factor-alpha (TGF-alpha) stimulates breast cancer cell proliferation is largely unknown. Furthermore, its potential role as an autocrine effector of estradiol-17 beta (E2)-stimulated growth of hormone-dependent mammary tumors remains controversial. Transient changes in phosph...

journal_title：Breast cancer research and treatment

authors： Etindi RN,Manni A,Martel J

更新日期：1992-01-01 00:00:00

abstract：:Conflicting opinions exist concerning clinical and pathological presentation, as well as evolution and prognosis, of breast cancer in young women. The roles of associated pregnancy and lactation on these parameters is also unclear. These two conditions are studied in the present work through the comparison of two brea...

journal_title：Breast cancer research and treatment

authors： Tabbane F,el May A,Hachiche M,Bahi J,Jaziri M,Cammoun M,Mourali N

更新日期：1985-01-01 00:00:00

abstract：:Triple-negative breast cancer is a particularly aggressive and lethal breast cancer subtype that is more likely to be interval-detected rather than screen-detected. The purpose of this study is to discover and initially validate novel early detection biomarkers for triple-negative breast cancer using preclinical sampl...

journal_title：Breast cancer research and treatment

authors： Li CI,Mirus JE,Zhang Y,Ramirez AB,Ladd JJ,Prentice RL,McIntosh MW,Hanash SM,Lampe PD

更新日期：2012-09-01 00:00:00

abstract：AIMS:To investigate the efficacy of letrozole 2.5 mg and 10 mg used as primary neoadjuvant therapy for patients with locally advanced and large operable breast cancer. PATIENTS AND METHODS:Twenty-four postmenopausal patients with locally advanced or large operable breast cancer were treated in two consecutive series w...

journal_title：Breast cancer research and treatment

authors： Dixon JM,Love CD,Bellamy CO,Cameron DA,Leonard RC,Smith H,Miller WR

更新日期：2001-04-01 00:00:00

abstract：:Transforming growth factor-beta (TGFB) is a potent inhibitor of normal epithelial cell proliferation, and may be one of the regulatory factors that are perturbed during tumor development. While many tumor cell lines no longer respond to the inhibitory effects of TGFB due to a reduction or absence of the type II recept...

journal_title：Breast cancer research and treatment

authors： Barlow J,Yandell D,Weaver D,Casey T,Plaut K

更新日期：2003-05-01 00:00:00

abstract：:Pathological complete response (pCR) is an important predictor of long-term survival in patients with breast cancer receiving neoadjuvant chemotherapy (NAC). At present, the accuracy of traditional radiological assessments during treatment in predicting pCR is poor. Unidimensional and 3D volumetric ultrasound measurem...

journal_title：Breast cancer research and treatment

authors： Gounaris I,Provenzano E,Vallier AL,Hiller L,Iddawela M,Hilborne S,Taylor K,Britton P,Earl HM,Sinnatamby R

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Central nervous system (CNS) relapse is increasing in breast cancer. This increase may reflect altered failure patterns from adjuvant therapy, more effective systemic therapy with improved control in non-CNS sites, or a resistant breast cancer subtype. METHODS:To determine the factors associated with clinic...

journal_title：Breast cancer research and treatment

authors： Carey LA,Ewend MG,Metzger R,Sawyer L,Dees EC,Sartor CI,Moore DT,Graham ML

更新日期：2004-12-01 00:00:00

abstract：:As the number of women surviving breast cancer increases, with implications for the health system, research into the physical and psychosocial sequelae of the cancer and its treatment is a priority. This research estimated self-reported health-related quality of life (HRQoL) associated with two rehabilitation interven...

journal_title：Breast cancer research and treatment

authors： Gordon LG,Battistutta D,Scuffham P,Tweeddale M,Newman B

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The Van Nuys Prognostic Index (VNPI) is a simple score for predicting the risk of local recurrence (LR) in patients with Ductal Carcinoma In Situ (DCIS) conservatively treated. This score combines three independent predictors of Local Recurrence. The VNPI has recently been updated with the addition of age as...

journal_title：Breast cancer research and treatment

authors： Di Saverio S,Catena F,Santini D,Ansaloni L,Fogacci T,Mignani S,Leone A,Gazzotti F,Gagliardi S,De Cataldis A,Taffurelli M

更新日期：2008-06-01 00:00:00