The emerging role of Vitamin D in asthma management.

Abstract:

PURPOSE:Vitamin D deficiency and asthma share risk factors. Epidemiologists suggest that the U.S. prevalence of Vitamin D deficiency has increased as a result of the Westernization of culture and less time spent outdoors. Numerous studies support a patient's Vitamin D deficiency as a contributing cause to increased asthma symptoms, lower lung function levels, increased airway reactivity, and worsening asthma control. The purpose of the review article is to discuss the emerging role of Vitamin D in asthma management. DATA SOURCES:A review of original research identified through MEDLINE and CINAHL and published in English was performed. CONCLUSIONS:Research suggests promising benefits of Vitamin D supplementation in asthma patients with low (<30 ng/mL) Vitamin D levels. Evidence supports several possible mechanisms, including downregulation of allergen sensitivity and enhanced steroid responsiveness. Studies demonstrate that Vitamin D modifies airway hyperresponsiveness by minimizing airway inflammation. Ongoing studies seek to further evaluate the effects of Vitamin D supplementation on asthma and asthma morbidity. IMPLICATIONS FOR PRACTICE:While there is no consensus on the use of Vitamin D as a mainstay in asthma treatment, research supports its consideration for use in asthma patients with low Vitamin D levels. Current evidence reinforces the need to measure Vitamin D levels for all asthma patients.

journal_name

J Am Assoc Nurse Pract

authors

Rance K

doi

10.1002/2327-6924.12062

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

263-7

issue

5

eissn

2327-6886

issn

2327-6924

journal_volume

26

pub_type

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