Toxin-induced cardiovascular failure.

Abstract:

:Adverse cardiovascular events comprise a large portion of the morbidity and mortality in drug overdose emergencies. Adverse cardiovascular events encountered by emergency physicians treating poisoned patients include myocardial injury, hemodynamic compromise with shock, tachydysrhythmias, and cardiac arrest. Early signs of toxin-induced cardiovascular failure include bradycardia, tachycardia, and specific ECG findings. Treatment of toxicologic tachycardia relies on rapid supportive care along with proper use of benzodiazepines for sedation. Treatment of toxicologic bradycardia consists of the use of isotonic fluids, atropine, calcium salts, and glucagon. High-dose insulin euglycemia should be used early in the course of suspected severe poisoning and intravenous lipid emulsion given to patients who suffer cardiac arrest.

authors

Jang DH,Spyres MB,Fox L,Manini AF

doi

10.1016/j.emc.2013.10.003

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

79-102

issue

1

eissn

0733-8627

issn

1558-0539

pii

S0733-8627(13)00094-1

journal_volume

32

pub_type

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