Abstract：
:Although numerous studies have shown that hypoxia affects cortisol and aldosterone production in vivo, the underlying molecular mechanisms regulating the steroidogenic genes of these steroid hormones are still poorly known. MicroRNAs are post-transcriptional regulators that control diverse biological processes and this study describes the identification and validation of the hypoxia-inducible microRNA, miR-10b, as a negative regulator of the CYP11B1 and CYP11B2 steroidogenic genes in H295R human adrenocortical cells. Using the human TaqMan Low Density miRNA Arrays, we determined the miRNA expression patterns in H295R cells under normoxic and hypoxic conditions, and in cells overexpressing the human HIF-1α. Computer analysis using three in silico algorithms predicted that the hypoxia-inducible miR-10b molecule targets CYP11B1 and CYP11B2 mRNAs. Gene transfection studies of luciferase constructs containing the 3'-untranslated region of CYP11B1 or CYP11B2, combined with miRNA overexpression and knockdown experiments provide compelling evidence that CYP11B1 and CYP11B2 mRNAs are likely targets of miR-10b.
journal_name
Mar Pollut Bulljournal_title
Marine pollution bulletinauthors
Nusrin S,Tong SK,Chaturvedi G,Wu RS,Giesy JP,Kong RYdoi
10.1016/j.marpolbul.2014.04.002subject
Has Abstractpub_date
2014-08-30 00:00:00pages
344-51issue
2eissn
0025-326Xissn
1879-3363pii
S0025-326X(14)00205-7journal_volume
85pub_type
杂志文章abstract：:This paper presents a high-resolution operational forecast system for providing support to oil spill response in Belfast Lough. The system comprises an operational oceanographic module coupled to an oil spill forecast module that is integrated in a user-friendly web application. The oceanographic module is based on De...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2016.09.042
更新日期：2017-01-15 00:00:00
abstract：:After the Deepwater Horizon oil spill, a MOSSFA (Marine Oil Snow Sedimentation and Flocculent Accumulation) event took place, transporting an estimated 14% of total released oil to the sediment, and smothering parts of the benthic ecosystem. This microcosm study describes the effects of oiled artificial marine snow on...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2017.11.028
更新日期：2018-01-01 00:00:00
abstract：:The Arabian or Persian Gulf is recognized as one of the warmest estuaries globally. The sea surface temperature (SST) has been utilized in several studies to gauge the global warming associated with climate change. In the current investigation we present detailed in situ SST measurements for five consecutive years (20...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2020.111766
更新日期：2020-12-01 00:00:00
abstract：:The scientific teams from the interdisciplinary Seine-Aval (SA) research program and the SA's operational pole, GIPSA (Groupement d'Intérêt Public Seine-Aval) have worked together to create a report card designed to help the Estuary Council (Conseil de l'Estuaire) revitalize its original functions: maintaining functio...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2007.10.011
更新日期：2008-01-01 00:00:00
abstract：:We tested the hypothesis that the poor recovery of the coral populations on reefs in the Florida Keys is related to low coral recruitment. In the summer of 2011, we deployed 240 terracotta tiles at eight study sites in a balanced design: (i) among three depths; and (ii) between fished and unfished reefs. Corals recrui...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2014.09.017
更新日期：2014-11-15 00:00:00
abstract：:A next-generation sequencing (NGS) approach, in conjunction with culture-based methods, was used to examine fungal and prokaryotic communities for the presence of potential pathogens in beach sands throughout Portugal. Culture-based fungal enumeration revealed low and variable concentrations of the species targeted (y...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2017.04.036
更新日期：2017-06-15 00:00:00
abstract：:Assessment of marine debris ingestion by sea turtles is important, especially to ensure their survival. From January to December 2011, 23 specimens of five species of sea turtles were found dead or dying after being rehabilitated, along the coast of the municipality of Rio de Janeiro, Brazil. To detect the presence of...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2015.10.002
更新日期：2015-12-30 00:00:00
abstract：:Citizen science programs carried out by volunteers are fundamental for the collection of scientific data on a wide spatial scale. From 2011 to 2018, 468 survey dives were conducted in 172 coastal locations of the Mediterranean Sea through Project AWARE's citizen science program, Dive Against Debris®. During the dives,...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2019.110763
更新日期：2020-01-01 00:00:00
abstract：:Sperm quality of the sea urchin, Anthocidaris crassispina, after exposure to environmentally realistic UV-B irradiances, was assessed by changes in sperm motility (measured by the computer-assisted sperm analysis (CASA) system), and related to subsequent fertilization success. Percentage motile sperm of A. crassispina...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/s0025-326x(01)00288-0
更新日期：2002-07-01 00:00:00
abstract：:The dominant source of coastal pollution adversely affecting the regional coastal water quality is the seasonally variable urban runoff discharged via southern California's rivers. Here, we use a surface transport model of coastal circulation driven by current maps from high frequency radar to compute two-year hindcas...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2014.11.004
更新日期：2015-01-15 00:00:00
abstract：:Surface sediments and clam Meretrix meretrix were collected from a northern estuarine region in Dongying City, China. Sediments were analysed for heavy metals (Hg, As, Cd, Cr, Cu, Pb, and Zn) and the clams were tested for metallothioneins (MTs) and lysosomal membrane stability (LMS). The heavy metal total concentratio...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2017.11.017
更新日期：2018-01-01 00:00:00
abstract：:According to 2014-2016 monitoring data, an assessment index system including water quality, depositional environment and ecosystem was built to evaluate the health statue of marine ecosystem in the Laizhou Bay using analytic hierarchy process (AHP) method. The results, spatialized in ArcGIS software, show: while the c...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2017.08.027
更新日期：2017-12-15 00:00:00
abstract：:Parallel studies on organic and elemental carbon in PM1 and PM2.5 aerosols and in wet deposition in various forms of its occurrence were conducted in the urbanised coastal zone of the Baltic Sea. The carbon load introduced into the sea water was mainly affected by the form of precipitation. Dry deposition load of carb...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2016.01.003
更新日期：2016-03-15 00:00:00
abstract：:Hydrodynamics play a critical role in determining the trajectory of an oil spill. Currents, stratification and mesoscale processes all contribute to how a spill behaves. Using an industry‑leading oil spill model, we compare forecasts of oil dispersion when forced with two different hydrodynamic models of the North-Wes...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2020.111258
更新日期：2020-07-01 00:00:00
abstract：:Despite widespread detection of microplastic pollution in marine environments, data describing microplastic abundance in urban estuaries and microplastic discharge via treated municipal wastewater are limited. This study presents information on abundance, distribution, and composition of microplastic at nine sites in ...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2016.05.077
更新日期：2016-08-15 00:00:00
abstract：:An important component of microplastic research is development of reproducible methods for microplastic recovery and characterization. Presented is a review of the literature comparing microplastic separation and identification methodologies from seawater, sediment and marine organisms. The efficiency of methods was e...
journal_title：Marine pollution bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.marpolbul.2017.08.058
更新日期：2017-10-15 00:00:00
abstract：:The Grand Banks south of Newfoundland provide year-round feeding habitat for tens of millions of seabirds of numerous species, an abundance and diversity unparalleled in the North Atlantic. Dense ship traffic routes traverse this productive environment as vessels travel the Great Circle Route between Europe and North ...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/S0025-326X(03)00250-9
更新日期：2003-09-01 00:00:00
abstract：:Production, respiration, egestion of faeces and excretion of ammonia were measured in competing early developmental stages of fish species (herring, smelt, perch and stickleback) to calculate their daily energy (food) requirements in the Vistula Lagoon, southern Baltic Sea. The highest consumption (per capita and per ...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2010.02.011
更新日期：2010-01-01 00:00:00
abstract：:The present work aimed at better understanding metal and metalloid bioaccumulation in the edible Pacific blue shrimp Litopenaeus stylirostris, using both laboratory and field approaches. In the laboratory, the bioaccumulation kinetics of Ag, Cd, Co, Cr, and Zn have been investigated in shrimp exposed via seawater and ...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2010.06.035
更新日期：2010-01-01 00:00:00
abstract：:We examined the spatial distribution and local characteristics of microplastics (0.33-5 mm) in surface water from six semi-enclosed bays and two coastal waters in Korea. Surveys were conducted in July from 2015 to 2017 using a Manta trawl. The mean abundance of total microplastics ranged from 1.12-4.74 particles/m3 am...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2019.110729
更新日期：2020-06-01 00:00:00
abstract：:The effects of prolonged exposure to reduced oxygen levels (3.0 and 1.5 mg O(2)l(-1)) on marine scavenging gastropods Nassarius festivus were studied for 8 weeks. The percentages of individuals engaged in feeding and amount of food consumed were reduced as oxygen level decreased; absorption efficiency, however, did no...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2008.03.039
更新日期：2008-01-01 00:00:00
abstract：:The characterization of inorganic elements in the produced water (PW) samples is a difficult task because of the complexity of the matrix. This work deals with a study of a methodology for dissolved Fe quantification in PW from oil industry by flame atomic absorption spectrometry (FAAS) after cloud point extraction (C...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2016.10.068
更新日期：2017-01-30 00:00:00
abstract：:Mussels (Mytilus spp.) are worldwide utilized in marine biomonitoring by a multi-biomarker approach. However, for a correct interpretation of different biomarker responses, information is needed on their natural seasonal variability due to environmental/physiological factors. In this work, the seasonal variations of d...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2017.01.035
更新日期：2017-03-15 00:00:00
abstract：:The degree of organotin compounds (OTCs), including dibutyltin, tributyltin, triphenyltin and dioctyltin, contamination in seafood purchased in 2017 and 2018 from Hong Kong market was studied. Edible portions of 341 seafood samples, including fish, crustaceans and molluscs, were used for analysis by gas chromatograph ...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2020.111116
更新日期：2020-05-01 00:00:00
abstract：:A primitive-equation model has been used to investigate the meteorologically-driven circulation of the Bay of Algeciras. It is shown that the mean circulation of Atlantic Water (AW) is characterized by an anticyclonic cell, while Mediterranean Water (MW) follows a preferred cyclonic pathway. Meteorological forcing dis...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2014.01.036
更新日期：2014-03-15 00:00:00
abstract：:Non-eroding silicone-based coatings can effectively reduce fouling of ship hulls and are an alternative to biocidal and heavy metal-based antifoulings. The products, whose formulations and make up are closely guarded proprietary knowledge, consist of a silicone resin matrix and may contain unbound silicone oils (1-10%...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2007.04.009
更新日期：2007-08-01 00:00:00
abstract：:There is significant risk associated with increased oil and gas exploration activities in the Arctic Ocean. This paper presents a probabilistic methodology for Ecological Risk Assessment (ERA) of accidental oil spills in this region. A fugacity approach is adopted to model the fate and transport of released oil, takin...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2018.08.030
更新日期：2018-10-01 00:00:00
abstract：:Eight metals in sediment samples at 15 sites from the Shantou Bay were analyzed with BCR sequential extraction protocol to obtain the metal distribution patterns in the bay. The results showed that the heavy metal pollutions in upper bay were more severe than in middle and down reaches of the bay. Both total and non-r...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2012.12.003
更新日期：2013-03-15 00:00:00
abstract：:The Bay of Fundy, Canada, is a macrotidal bay with a highly productive intertidal zone, hosting a large abundance and diversity of marine invertebrates. We analysed trace element concentrations and stable isotopic values of δ(15)N and δ(13)C in 14 species of benthic marine invertebrates from the Bay of Fundy's interti...
journal_title：Marine pollution bulletin
pub_type： 杂志文章
doi：10.1016/j.marpolbul.2015.09.046
更新日期：2015-12-15 00:00:00
abstract：:This review quantifies plastic interaction in marine biota. Firstly, entanglement and ingestion records for all marine birds, mammals, turtles, fish, and invertebrate species, are summarized from 747 studies. Marine debris affected 914 species through entanglement and/or ingestion. Ingestion was recorded for 701 speci...
journal_title：Marine pollution bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.marpolbul.2019.110858
更新日期：2020-02-01 00:00:00
