Abstract:
OBJECTIVE:To evaluate the development of natural orifice transluminal endoscopic surgery (NOTES) transvaginal nephrectomy and present the initial experience. METHODS:Thirty-eight female patients were submitted to hybrid NOTES transvaginal nephrectomy for tumor (n=23) and nonfunctioning renal unit (n=15) in 2 academic medical centers. Patients underwent surgery from July 2010 to June 2012 and none of them were candidates for partial nephrectomy (clinical stage T1b or higher). The procedure was performed by the use of multi-instrument ports or flexible cannulas inserted through umbilical and vaginal incisions. A 30° lens extra-long camera and combinations of conventional laparoscopic and prebent instruments were used. Specially designed extra-long, prebent straight instruments were found to be particularly useful for transvaginal manipulations. Prospective data regarding patient demographics, intraoperative and postoperative course of the patients, and pathology results were collected. RESULTS:Average tumor diameter was 6 cm (range, 4.9-7.5 cm). Average operative time was 114.1 minutes (range, 90-190 minutes). Estimated blood loss ranged between 50 and 150 mL (average, 80 mL). Intraoperatively, 2 bladder perforations occurred and were treated by suturing. Postoperatively, 2 patients suffered from fever of unknown origin and 2 patients required transfusions due to bleeding. Average hospital stay was 3.3 days (range, 3-5 days). Positive surgical margins were not detected. CONCLUSION:Hybrid NOTES transvaginal nephrectomy is a feasible and safe alternative to standard laparoscopic nephrectomy in selected patients. Difficulties arising from limitations in current instrumentation have been addressed by the use of specially designed instruments. Further clinical studies are required to ascertain this approaches' place among nephrectomy techniques.
journal_name
Urologyjournal_title
Urologyauthors
Georgiopoulos I,Kallidonis P,Kyriazis I,Adonakis G,Stolzenburg JU,Schwentner C,Liatsikos Edoi
10.1016/j.urology.2014.01.055subject
Has Abstractpub_date
2014-07-01 00:00:00pages
99-104issue
1eissn
0090-4295issn
1527-9995pii
S0090-4295(14)00269-6journal_volume
84pub_type
杂志文章,多中心研究相关文献
UROLOGY文献大全abstract::Radiation complications, after definitive treatment of localized prostatic carcinoma by either external beam or interstitial implantation with Iodine-125 seeds, are reviewed. Late serious complications to immediately adjacent structures of the anterior rectal wall, prostatic urethra, bladder neck, and external sphinct...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(83)90038-9
更新日期:1983-05-01 00:00:00
abstract::Ninety-three cases of germinal testicular tumors with urinary gonadotropin (HCG) values, estimated by biologic or radioimmunoassay techniques, were reviewed. Preoperative values of HCG and subsequent postoperative values were related to response to treatment and prognosis. Twenty-five patients (26.9 per cent) comprise...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(75)90074-6
更新日期:1975-04-01 00:00:00
abstract:OBJECTIVES:The presence of metastatic lesions is the only acceptable fact to confirm malignant pheochromocytoma. Patients with malignant pheochromocytomas, however, have a very poor survival rate. The aim of our study was to postulate predictive values for malignant pheochromocytomas. METHODS:We evaluated symptoms, di...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00612-8
更新日期:1999-04-01 00:00:00
abstract::In a patient with undiagnosed right renal tuberculosis miliary spread to both lungs developed following ureteral catheterization. Mycobacteremia with miliary metastatic foci should be considered as a complication of urinary tract instrumentation in the presence of renal tuberculosis. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(80)90084-9
更新日期:1980-08-01 00:00:00
abstract:OBJECTIVES:Numerous techniques have been described for supporting the vaginal vault after enterocele repair and hysterectomy. We describe a transvaginal culdosuspension that obliterates the cul-de-sac and supports the vaginal cuff high on the levator plate. The normal vaginal axis is restored, and adequate vaginal dept...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(99)00266-6
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVES:To assess the efficacy and safety of the thermoexpandable hourglass-shaped nitinol prostatic stent in the treatment of patients with lower urinary tract symptoms due to bladder outlet obstruction. METHODS:The stents were inserted in an outpatient setting under local anesthesia and direct vision. Five differ...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/j.urology.2005.04.030
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To determine the efficacy of computed tomography of the chest (CTC) and plain radiograph (CXR) in the initial staging process of testicular germ cell tumors. METHODS:The medical records of 362 patients with testicular germ cell tumor treated at our center between January 1980 and August 1993 were reviewed wi...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(94)80139-8
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVES:To examine the usefulness of pretreatment testicular sperm extraction because some patients have tumor-induced azoospermia. In view of the high cure rates for testicular germ cell tumors and malignant lymphomas, increasing clinical importance is attached to protecting fertility. High-dose cytostatic therapy ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(02)02264-1
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:To find clinical or radiographic factors that are associated with angioembolization failure after high-grade renal trauma. MATERIAL AND METHODS:Patients were selected from the Multi-institutional Genito-Urinary Trauma Study. Included were patients who initially received renal angioembolization after high-gra...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.10.027
更新日期:2020-10-28 00:00:00
abstract:OBJECTIVES:To review the experience of 40 consecutive patients who underwent radical retropubic prostatectomy and to determine if and how the procedure could be performed safely on an ambulatory basis. METHODS:Between June 20, 1994 and November 26, 1996, 40 consecutive men with clinically localized prostate carcinoma ...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(97)00716-4
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To compare the outcomes of active surveillance (AS) series between African American men (AAM) and non-AAM diagnosed with low-risk prostate cancer at 3 medical centers. METHODS:Between 2005 and 2012, 214 men accepted AS on the basis of favorable clinical features and parameters after initial and repeat biopsy...
journal_title:Urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.urology.2013.09.038
更新日期:2014-02-01 00:00:00
abstract::Two cases of megalourethra are presented, the ninth and tenth cases to be documented in the literature. Both patients exhibited mesodermal abnormalities which justify categorization among the minor forms of prune belly syndrome. One patient, the youngest to have undergone surgical correction, presented with azotemia, ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(78)90366-7
更新日期:1978-07-01 00:00:00
abstract:OBJECTIVES:To assess the practice preferences among urologists treating superficial bladder cancer in the United States. METHODS:We surveyed 226 urologists using a specially designed survey instrument. The type of practice, number of urologists in group practice, annual volume of patients with bladder cancer, and thos...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(03)00765-9
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVES:To examine the effect of preoperative stent placement on total cost of ureteroscopic stone intervention. Passive ureteral dilation with a preoperative ureteral stent has been proposed as a method to facilitate both upper tract access and stone removal. METHODS:We retrospectively reviewed the records of pati...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.03.055
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the efficacy of laparoscopic radical nephrectomy for patients with small renal cell carcinoma by comparing the clinical results of patients treated laparoscopically with those of patients treated with traditional open radical nephrectomy. METHODS:Of 100 patients with localized, small (less than ...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(98)00505-6
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:To show the noninferiority of silodosin 8-mg once-daily (QD) to 4-mg twice-daily (BID) in efficacy and safety in patients with lower urinary tract symptoms or benign prostatic hyperplasia in the Korean population. METHODS:A prospective, multicenter, double-blind, randomized, comparative study was conducted. ...
journal_title:Urology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.urology.2013.11.013
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To present the results of a Phase II trial of thalidomide and interferon-alpha in renal cell carcinoma. METHODS:Patients with metastatic clear cell renal cell carcinoma and no prior systemic therapy were accrued. Interferon-alpha was administered at 5 million units subcutaneously three times per week. Thali...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/j.urology.2004.01.035
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:To investigate the role of phospholipase Cε (PLCε) by silencing PLCε with short hairpin RNA (shRNA) in human bladder cancer cells BIU-87 in vitro and in vivo. METHODS:A PLCε shRNA expression vector was transfected into BIU-87 cells, and the expression of PLCε protein was detected by Western blotting. Cell p...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.03.014
更新日期:2011-08-01 00:00:00
abstract::An eight-year-old boy had periumbilical pain associated with micturition; the disorder was secondary to a persistent urachal band. Surgical excision of the urachus resulted in resolution of the symptoms. Although urachal anomalies are unusual, they should be considered in the differential diagnosis of periumbilical pa...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)90034-6
更新日期:1988-12-01 00:00:00
abstract::Transabdominal ultrasonography of the bladder was performed in 25 examinations on 20 patients being treated for bladder carcinoma. The presence or absence of tumor was accurately gauged in all 20 patients. As compared to cystoscopy, tumor staging was less accurate. Eleven of 15 patients with tumor present were accurat...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(87)90526-7
更新日期:1987-04-01 00:00:00
abstract:OBJECTIVES:To clarify the clinical and prognostic significance of cortactin and phosphorylated cortactin in patients with sarcomatoid renal cell carcinoma (SRCC). METHODS:We retrospectively reviewed the data from 31 patients with SRCC and 33 with conventional renal cell carcinoma matched for clinicopathologic features...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.03.019
更新日期:2011-08-01 00:00:00
abstract::A 30-year-old man presented with intermittent leak of straw-colored fluid from his left lateral thigh, which on evaluation was diagnosed as prostatocutaneous fistula. Exploration and revision anastomotic urethroplasty was done and the patient remains asymptomatic in follow-up. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2013.04.023
更新日期:2013-08-01 00:00:00
abstract::Percutaneous ureteral splinting using a modified catheter technique is described, and experience in treating 5 patients (4 with postoperative fistulas and 1 with stricture) is reported. The method offers an effective alternative to surgery in achieving ureteral splinting and renal drainage. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(77)90022-x
更新日期:1977-08-01 00:00:00
abstract:OBJECTIVES:To describe and assess the efficacy for increased glandular destruction by using 6 to 8 cryoprobes in place of the traditional 5 probes. METHODS:In April 1996, a revised method for cryosurgery was begun that uses 6 to 8 cryoprobes, and by July 1997, 81 men had been treated. This group was compared retrospec...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(99)00039-4
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:To introduce our hybrid technique using a Satinsky clamp for right-sided hand-assisted laparoscopic donor nephrectomy (HALDN) and to compare its effectiveness and safety with those of standard left-sided HALDN. METHODS:We conducted a retrospective analysis of 253 patients, who underwent HALDN (51 right and 2...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2014.09.006
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:Determining the genetic changes associated with the development of metastatic prostate cancer is of utmost importance in patient prognosis and therapy. Our goal is to identify genes whose enhanced expression is associated with metastatic prostate cancer. METHODS:Total ribonucleic acid was isolated from pros...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/S0090-4295(96)00207-5
更新日期:1996-09-01 00:00:00
abstract::The "female prostate" denotes an impression on the base of the female bladder resembling the enlarged male prostate radiographically. Though the finding is widely recognized, confusion exists as to its significance. The differential diagnosis is moderately extensive, and includes retroverted uterus, anterior vaginal t...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(82)90211-4
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVES:To investigate the efficacy of pazopanib, both alone and in combination with docetaxel, in bladder cancer cells. Bladder cancer expresses many potential therapeutic targets of biological agents, including the vascular endothelial growth factor receptor (VEGFR). Pazopanib is a small molecule inhibitor of VEGF...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.02.041
更新日期:2011-07-01 00:00:00
abstract::A new type of nephrostomy is described with the following main characteristics: it uses a small multiperforated Silastic tube; its crosswise location allows perfect drainage of all of the calyces and the pelvis; it does not become obstructed nor move from its position; and it causes minimum traumatization of the renal...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(77)90305-3
更新日期:1977-06-01 00:00:00
abstract:OBJECTIVES:Diabetes mellitus (DM) is an important cause of organic impotence. It is estimated that 35% to 75% of diabetic patients are impotent. In the present study we investigated the effect of experimentally induced diabetes (streptozocin 60 mg/kg, intraperitoneally, for 9 weeks) on sexual behavior and compared it t...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/S0090-4295(99)80073-9
更新日期:1995-04-01 00:00:00