Bone penetration of antibiotics.

Abstract:

:Osteomyelitis is caused by bacterial pathogens and, less frequently, by other infectious agents. Treatment of osteomyelitis should include a course of antimicrobial therapy with a batericidal agent. This therapy should be directed at the causative bacteria isolated by bone biopsy and culture, not by wound swab cultures above the infected bone. The bactericidal agent should be demonstrated effective against the organism isolated from bone and should penetrate the bone in sufficient concentrations. Many studies have assessed bone penetration of antimicrobials, but methodological problems must be addressed. Penicillins, cephalosporins, aminoglycosides, erythromycin, lincomycin and clindamycin, and metronidazole have all been evaluated.

journal_name

Orthopedics

journal_title

Orthopedics

authors

Smith BR,Rolston KV,LeFrock JL,Bayliff C

doi

10.3928/0147-7447-19830201-10

subject

Has Abstract

pub_date

1983-02-01 00:00:00

pages

187-93

issue

2

eissn

0147-7447

issn

1938-2367

journal_volume

6

pub_type

社论
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    abstract::This study compared the revision rates after autograft and allograft bone-patella tendon-bone anterior cruciate ligament (ACL) reconstruction. All bone-patella tendon-bone ACL reconstructions performed by a single surgeon between January 2000 and December 2006 were identified by retrospective chart review. Two hundred...

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    authors: Mehta VM,Mandala C,Foster D,Petsche TS

    更新日期:2010-01-01 00:00:00

  • Chemoprophylaxis without intra-articular wound drainage can replace autotransfusion in primary TKA.

    abstract::We compared outcomes in 2 groups undergoing total knee arthroplasty (TKA) with different blood-saving strategies (ie, chemoprophylaxis vs reinfusion). We hypothesized that chemoprophylaxis would lead to reduced blood loss and fewer transfusions, with no increase in associated complications. Group A was a prospective s...

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    doi:10.3928/01477447-20110427-11

    authors: Hourlier H,Fennema P

    更新日期:2011-06-14 00:00:00

  • Pigmented villonodular synovitis: a clinical analysis of twenty-four cases treated at Henry ford hospital.

    abstract::This article describes the clinical findings, roentgenographic manifestations, gross and microscopic pathology, treatment, and results of 24 cases of pigmented villonodular synovitis treated at Henry Ford Hospital over a period of 25 years. We conclude that synovectomy is the treatment of choice, and we have experienc...

    journal_title:Orthopedics

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    authors: Wu KK,Ross PM,Guise ER

    更新日期:1980-08-01 00:00:00

  • Patient experience with mupirocin or povidone-iodine nasal decolonization.

    abstract::Led by the federal government, the payers of health care are enacting policies designed to base provider reimbursement on the quality of care they render. This study evaluated and compared patient experiences and satisfaction with nasal decolonization with either nasal povidone-iodine (PI) or nasal mupirocin ointment ...

    journal_title:Orthopedics

    pub_type: 杂志文章,随机对照试验

    doi:10.3928/01477447-20140528-59

    authors: Maslow J,Hutzler L,Cuff G,Rosenberg A,Phillips M,Bosco J

    更新日期:2014-06-01 00:00:00

  • Repair of full-thickness cartilage defects in rabbit knees with free periosteal graft preincubated with transforming growth factor.

    abstract::This study compared different concentrations of transforming growth factor-beta 1 (TGF-beta1) used for short-term preincubation in vitro of large periosteal explants to determine the effect of chondrogenesis and the fate of repair cartilage over time. Eighty-two rabbits were divided into four groups: group A, non-graf...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Hsieh PC,Thanapipatsiri S,Anderson PC,Wang GJ,Balian G

    更新日期:2003-04-01 00:00:00

  • Slipped capital femoral epiphysis: long-term results of an abandoned technique.

    abstract::Sixty-two (11 women and 51 men) of 76 consecutive patients treated between January 1960 and December 1979 with percutaneous pinning, traction, and ambulation in Thomas splints for slipped capital femoral epiphyses (physiolysis colli femoris; PCF) were re-examined radiologically and clinically to evaluate long-term res...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Steinke MS,Mikkelsen SS,Jensen HP,Thomsen PB

    更新日期:1991-02-01 00:00:00

  • Augmentation of bone healing by specific frequency and amplitude compressive strains.

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    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Shadmehr A,Esteki A,Oliaie GR,Torkaman G,Sabbaghian A

    更新日期:2009-03-01 00:00:00

  • The diabetic foot: update on a common clinical syndrome.

    abstract::A cross-sectional study was conducted in 3995 non-hospitalized diabetic patients to evaluate symptoms commonly associated with "diabetic foot" syndrome. Each patient was examined twice over 2 years during routine follow-up. The male/female ratio differed significantly between the study group and general population. Me...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Stein H,Yaacobi E,Steinberg R

    更新日期:2003-11-01 00:00:00

  • Biomechanical comparison of interference screw and cortical button with screw hybrid technique for distal biceps brachii tendon repair.

    abstract::Various fixation techniques have been described for ruptured distal biceps tendons. The authors hypothesized that no significant differences would be found between the mean failure strength, maximum strength, and stiffness of the interference screw and hybrid technique. Fourteen fresh-frozen human cadaveric elbows wer...

    journal_title:Orthopedics

    pub_type: 杂志文章,随机对照试验

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    authors: Arianjam A,Camisa W,Leasure JM,Montgomery WH

    更新日期:2013-11-01 00:00:00

  • Historical update and new developments on the EMG-force relationships of skeletal muscles.

    abstract::The EMG-force relationships of skeletal muscles are of significant interest to the orthopedic-biomechanics researcher and have been a topic of interest and controversy for the last three decades. We present the developments reported in the literature, from the early 1950s, relevant to this topic, outlining the details...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Solomonow M,Baratta R,Zhou BH,Shoji H,D'Ambrosia R

    更新日期:1986-11-01 00:00:00

  • Finite element analysis of 3 posterior fixation techniques in the lumbar spine.

    abstract::This study compared the biomechanics of 3 fixation techniques: bilateral pedicle screw (BPS) fixation, unilateral pedicle screw (UPS) fixation, and UPS supplemented with translaminar facet screw (UPS+TLFS) fixation. The study was conducted in an L3-L5 finite element model. Three different finite element models were cr...

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    authors: Gong Z,Chen Z,Feng Z,Cao Y,Jiang C,Jiang X

    更新日期:2014-05-01 00:00:00

  • Femoral neck shortening after internal fixation of a femoral neck fracture.

    abstract::This study assesses femoral neck shortening and its effect on gait pattern and muscle strength in patients with femoral neck fractures treated with internal fixation. Seventy-six patients from a multicenter randomized controlled trial participated. Patient characteristics and Short Form 12 and Western Ontario and McMa...

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    pub_type: 杂志文章,随机对照试验

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    authors: Zielinski SM,Keijsers NL,Praet SF,Heetveld MJ,Bhandari M,Wilssens JP,Patka P,Van Lieshout EM,FAITH Trial Investigators.

    更新日期:2013-07-01 00:00:00

  • Infantile tibia vara: correction of recurrent varus deformity following epiphyseolysis.

    abstract::Infantile tibia vara (infantile Blount's disease) is a condition in which progressive varus of the knee develops due to diminished physeal growth of the medial aspect of the proximal tibia. A 6-year-old boy with severe bilateral infantile tibia vara (Langenskiold stage V) underwent operative correction of his deformit...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:10.3928/01477447-20080501-10

    authors: Gary J,Richards BS

    更新日期:2008-05-01 00:00:00

  • Pediatric Supracondylar Humerus Fracture Outcomes by Pediatric and Nonpediatric Orthopedists.

    abstract::Pediatric supracondylar humerus fractures are common and often require surgical intervention by an orthopedic surgeon, who may or may not have pediatric subspecialty training. This study used a large national database to assess for potential differences in perioperative outcomes for pediatric supracondylar humerus fra...

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  • Multiligamentous knee injury concomitant with a patellar tendon rupture.

    abstract::Multiligamentous knee injuries with simultaneous patellar tendon ruptures are rare. Surgeons must be prepared to address injured structures of the knee to allow return of knee function. Restoring motion while protecting repairs is important. The authors present 2 cases and discuss treatment strategy for preoperative e...

    journal_title:Orthopedics

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    authors: Brunkhorst J,Johnson DL

    更新日期:2015-01-01 00:00:00

  • Low-grade cartilage tumors: diagnosis and treatment.

    abstract::As a result of reading this article, physicians should be able to: 1. List the features that are useful in differentiating a low-grade chondrosarcoma from an enchondroma. 2. Describe the treatment principles of low-grade cartilage tumors based on the anatomic location and stage of the tumor. 3. Discuss the characteris...

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    pub_type: 杂志文章,评审

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    authors: Ryzewicz M,Manaster BJ,Naar E,Lindeque B

    更新日期:2007-01-01 00:00:00

  • Synovial chondromatosis of pes anserine bursa secondary to osteochondroma.

    abstract::Osteochondromas are common benign bone tumors. Synovial chondromatosis is a benign cartilaginous metaplasia that occurs in the synovium. The authors describe a unique case of synovial chondromatosis developing in the pes anserine bursa secondary to an underlying osteochondroma of the proximal medial tibia. It is unusu...

    journal_title:Orthopedics

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    authors: Shallop B,Abraham JA

    更新日期:2014-08-01 00:00:00

  • Survival, Tumor Recurrence, and Function Following Shoulder Girdle Limb Salvage at 24 to 35 Years of Follow-up.

    abstract::Limb salvage is the treatment of choice for malignant shoulder girdle tumors; however, there is a paucity of data examining the long-term outcome. The authors have previously reported on a cohort of patients at short- and mid-term follow-up. The purpose of this study was to report the long-term outcome of shoulder rec...

    journal_title:Orthopedics

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    authors: Scorianz M,Houdek MT,Sherman CE,Sim FH,O'Connor MI

    更新日期:2019-11-01 00:00:00

  • Degenerative changes of the lumbar spine: assessment by computed tomography.

    abstract::Degenerative changes of the lumbar spine may occur in either the anterior or posterior intervertebral articulations. Computed tomography is an ideal modality in evaluating these processes because of its optimal plane of section and its ability to image both osseous and soft tissue structures. ...

    journal_title:Orthopedics

    pub_type: 社论

    doi:10.3928/0147-7447-19810201-13

    authors: Raskin SP

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  • Knee arthroscopy with local anesthesia in ambulatory patients. Methods, results and patient compliance.

    abstract::Knee arthroscopy in locally anesthetized ambulatory patients has been performed by filling the knee joint with 50 ml to 60 ml of 0.5% prilocaine, with adrenaline and with additional local infiltration at the sites of puncture. During the arthroscopic procedure the joint cavity is further distended with a mixture of th...

    journal_title:Orthopedics

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    doi:

    authors: Eriksson E,Häggmark T,Saartok T,Sebik A,Ortengren B

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  • Hematogenous septic arthritis of the adult hip.

    abstract::A retrospective review of 10 patients admitted to 4 regional hospitals between 1987 and 1997 in whom acute septic hip arthritis was diagnosed was performed to compare presentation, laboratory and radiographic findings, treatment, and outcome. Patients presented with fever, hip or groin pain, and an inability to bear w...

    journal_title:Orthopedics

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Yeargan SA 3rd,Perry JJ,Kane TJ 3rd,Richardson AB

    更新日期:2003-08-01 00:00:00

  • Peri-implant Fractures Following Hook Plate Fixation for Unstable Distal Clavicle Fractures.

    abstract::Clavicle hook plate is a common implant for treating distal clavicle fracture. Although high bone union rate and good functional outcome have been reported, so have several complications, such as osteolysis and fracture of the acromion, loss reduction, hook impingement, and rotator cuff tear. Peri-implant fracture ove...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:10.3928/01477447-20200619-01

    authors: Ni PL,Lin KC,Chen CY,Tarng YW,Chang WN,Renn JH

    更新日期:2020-09-01 00:00:00

  • Philosophy of osteosynthesis in shoulder fractures.

    abstract::A wide range of workable instrumentation is available for the treatment of proximal humeral fractures, whereas osteosynthesis of scapular fractures is commonly achieved by plate/screw fixation. Older persons are confronted with a steadily rising incidence of osteoporotic fractures. Especially for this group of patient...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Fleischmann W,Kinzl L

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  • The role of anterior surgery in the treatment of thoracolumbar fractures.

    abstract::Operative treatment of thoracolumbar burst fractures or fracture dislocations is a relatively modern development. Anterior decompression and stabilization play a significant role in the treatment of thoracolumbar burst fractures. This article reviews the clinical indications and describes a one-staged operative techni...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: McGuire RA Jr

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  • Management of nonunion associated with broken intramedullary nail of the femur.

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    journal_title:Orthopedics

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  • Surgical decompression for cervical spondylotic myelopathy: correlation between operative outcomes and MRI of the spinal cord.

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    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Papadopoulos CA,Katonis P,Papagelopoulos PJ,Karampekios S,Hadjipavlou AG

    更新日期:2004-10-01 00:00:00

  • Magnetic resonance imaging in the evaluation of heel pain.

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    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:

    authors: Hall RL,Erickson SJ,Shereff MJ,Johnson JE,Kneeland JB

    更新日期:1996-03-01 00:00:00

  • Lateralized Center of Rotation and Lower Neck-Shaft Angle Are Associated With Lower Rates of Scapular Notching and Heterotopic Ossification and Improved Pain for Reverse Shoulder Arthroplasty at 1 Year.

    abstract::Heterotopic ossification and scapular notching are common following reverse total shoulder arthroplasty. Compared with the original Grammont-style prosthesis with a medialized center of rotation (COR) and a 155° neck-shaft angle, lateralization of COR and reduction of neck-shaft angle have been associated with decreas...

    journal_title:Orthopedics

    pub_type: 杂志文章

    doi:10.3928/01477447-20180613-01

    authors: Nelson R,Lowe JT,Lawler SM,Fitzgerald M,Mantell MT,Jawa A

    更新日期:2018-07-01 00:00:00

  • Rotational alignment of the tibial component in total knee arthroplasty.

    abstract::This study compares two different methods of aligning the tibial component in a total knee arthroplasty, one by aligning the component with the border between the medial one third and lateral two thirds of the tibial tubercle and the other by allowing the component to seek its own position as the knee is taken through...

    journal_title:Orthopedics

    pub_type: 杂志文章,评审

    doi:

    authors: Bindelglass DF

    更新日期:2001-11-01 00:00:00

  • Fixation of multifragmentary patella fractures using a bilateral fixed-angle plate.

    abstract::This biomechanical study is the first to compare 3 fixation methods-bilateral fixed-angle plate, modified anterior tension wiring, and cannulated lag screws with anterior tension wiring-in multifragmentary distal patella fractures. A T-shaped 3-part fracture simulating a multifragmentary articular distal patella fract...

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    pub_type: 杂志文章

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    authors: Thelen S,Betsch M,Schneppendahl J,Grassmann J,Hakimi M,Eichler C,Windolf J,Wild M

    更新日期:2013-11-01 00:00:00