Correlation between magnetic resonance imaging grading and pathological grading in meningioma.

Abstract:

OBJECT:This study investigated the specific preoperative MRI features of patients with intracranial meningiomas that correlate with pathological grade and provide appropriate preoperative planning. METHODS:From 2006 to 2012, 120 patients (36 men and 84 women, age range 20-89 years) with newly diagnosed symptomatic intracranial meningiomas undergoing resection were retrospectively analyzed in terms of radiological features of preoperative MRI. There were 90 WHO Grade I and 30 WHO Grade II or III meningiomas. The relationships between MRI features and WHO histopathological grade were analyzed and scored quantitatively. RESULTS:According to the results of multivariate logistic regression analysis, age ≥ 75 years, indistinct tumorbrain interface, positive capsular enhancement, and heterogeneous tumor enhancement were identified factors in the prediction of advanced histopathological grade. The prediction model was quantified as a scoring scale: 2 × (age) + 5 × (tumor-brain interface) + 3 × (capsular enhancement) + 2 × (tumor enhancement). The calculated score correlated positively with the probability of high-grade meningioma. CONCLUSIONS:This scoring approach may be useful for clinicians in determining therapeutic strategy and in surgical planning for patients with intracranial meningiomas.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Lin BJ,Chou KN,Kao HW,Lin C,Tsai WC,Feng SW,Lee MS,Hueng DY

doi

10.3171/2014.7.JNS132359

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

1201-8

issue

5

eissn

0022-3085

issn

1933-0693

journal_volume

121

pub_type

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