Abstract：
OBJECT:The goal of this study was to provide epidemiological and clinical data on the management of cavernomas of the basal ganglia and brainstem from a long-term series at one institution. METHODS:All 68 patients who were referred to the authors' department between 1992 and 2000 for deep cavernomas were evaluated by clinic examinations, review of neuroimaging examinations, and review of charts and operative notes. Twenty-nine patients underwent microsurgical procedures, which carried a 69% risk of transitory neurological deterioration. Radical excision was achieved in 25 of these patients, as determined by a review of neuroimages; the remaining four patients all experienced new hemorrhages that led to increased morbidity or even to mortality. Surgical results were better if surgery was performed early, within 1 month posthemorrhage, than if operations were postponed. In selected patients, deep lesions not reaching a pial surface could be safely removed from the thalamus, basal ganglia, or medulla oblongata. Of five patients who underwent gamma knife surgery, two experienced hemorrhages, one at 2 and the other at 5 years following treatment. Patients who did not undergo surgery had a yearly incidence of hemorrhage that was 2% in cases of incidental cavernomas and 7% in symptomatic ones. CONCLUSIONS:Over the long term, outcomes were worse following conservative treatment or shunt insertion surgery than after microsurgery of symptomatic cavernomas. Incidental cavernomas carried a low risk of neurological deterioration. Surgery should follow generally accepted indications, but only with the confidence that total removal can be safely achieved. Surgery that is performed within 10 to 30 days following ictus may be preferable to delayed surgery.
journal_name
J Neurosurgjournal_title
Journal of neurosurgeryauthors
Mathiesen T,Edner G,Kihlström Ldoi
10.3171/jns.2003.99.1.0031subject
Has Abstractpub_date
2003-07-01 00:00:00pages
31-7issue
1eissn
0022-3085issn
1933-0693journal_volume
99pub_type
杂志文章abstract：:The case of General Leonard Wood is notable both for its contribution to the field of neurosurgery and its historical significance. As one of Harvey Cushing's first successful brain tumor operations in 1910, Wood's surgery was part of the case series that culminated in Cushing's monograph Meningioma. This case was imp...
journal_title：Journal of neurosurgery
pub_type： 传,历史文章,杂志文章
doi：10.3171/2011.7.JNS102067
更新日期：2011-12-01 00:00:00
abstract：:Five full-term neonates with a posterior fossa subdural hematoma caused by birth injury are reported. All of the patients were successfully treated with surgery. They all presented with biphasic ventricular dilatation as demonstrated by serial computerized tomography (CT) scanning. The initial dilatation due to obstru...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1988.68.2.0211
更新日期：1988-02-01 00:00:00
abstract：:A patient with findings of bilateral cortical blindness and a unilateral carotid bruit is reported. A persistent trigeminal artery allowed emboli from a unilateral ulcerated internal carotid plaque to affect the visual cortex bilaterally. The angiographic findings and a brief discussion of this anomalous artery are pr...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1980.52.5.0709
更新日期：1980-05-01 00:00:00
abstract：:Saccular aneurysms arising at locations other than at arterial divisions are extremely rare. The authors describe eight such aneurysms that protruded from the dorsal wall of the internal carotid artery (ICA) and were unrelated to any arterial junction. Radical surgery was performed in all eight cases. The aneurysms we...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1986.65.3.0303
更新日期：1986-09-01 00:00:00
abstract：OBJECTIVE:Keyhole approaches, namely the minipterional approach (MPTa) and the supraorbital approach (SOa), are alternatives to the standard pterional approach to treat lesions located in the anterior and middle cranial fossae. Despite their increasing popularity and acceptance, the indications and limitations of these...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2019.12.JNS193196
更新日期：2020-03-13 00:00:00
abstract：:The Vanderbilt University Hospital heritage was influenced by the excellence of the Johns Hopkins era--by Osler, Halsted, Cushing, Brooks, and many others. Upon this strong origin, the neurosurgery department was built by Cobb Pilcher and perpetuated by William F. Meacham. ...
journal_title：Journal of neurosurgery
pub_type： 历史文章,杂志文章
doi：10.3171/jns.1993.79.3.0464
更新日期：1993-09-01 00:00:00
abstract：:The effect of intravenous nimodipine on the incidence of mortality and delayed ischemic neurological deficits of patients after aneurysmal subarachnoid hemorrhage (SAH) and surgery was studied in a prospective double-blind placebo-controlled trial. Upon admission, all of the patients were in Grades I to III according ...
journal_title：Journal of neurosurgery
pub_type： 临床试验,杂志文章
doi：10.3171/jns.1988.69.5.0683
更新日期：1988-11-01 00:00:00
abstract：OBJECT:Intracranial aneurysms of the anterior circulation might become symptomatic by causing visual deficits. The influence of treatment modality on improvement is still unclear. The objective of this study was to analyze the recovery of visual deficits caused by the mass effect of intracranial aneurysms after surgica...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/2011.5.JNS101983
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:Ossification of pterygoalar and pterygospinous ligaments traversing the superior aspect of the infratemporal fossa results in formation of osseous bars that can obstruct percutaneous needle access to the trigeminal ganglion through the foramen ovale (FO), interfere with lateral mandibular nerve block, and imp...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2019.2.JNS182709
更新日期：2019-05-10 00:00:00
abstract：:Intracranial extraaxial cavernous angiomas are rare vascular malformations. Their occurrence at the geniculate ganglion of the facial nerve within the temporal bone is exceptional. The authors describe a 35-year-old man who developed a slowly progressing facial palsy. Initial cranial MR imaging showed no pathological ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/JNS/2008/109/11/0893
更新日期：2008-11-01 00:00:00
abstract：:OBJECTIVE A subset of patients with Chiari I malformation demonstrate patent subarachnoid spaces around the cerebellum, indicating that reduced posterior fossa volume alone does not account for tonsillar descent. The authors distinguish two subsets of Chiari I malformation patients based on the degree of "posterior fo...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2016.6.JNS152998
更新日期：2017-06-01 00:00:00
abstract：:OBJECTIVEThe aim of this study was to derive a clinically applicable decision rule using clinical, radiological, and laboratory data to predict the development of delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH) patients.METHODSPatients presenting over a consecutive 9-year period with subar...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2018.1.JNS172715
更新日期：2018-06-01 00:00:00
abstract：:During a period of 3 years, 25 patients with intra- and extrasellar macroprolactinomas were pretreated with dopamine agonists for a period of 2 to 6 1/2 weeks prior to transsphenoidal microsurgical tumor resection. Dopamine agonists were administered orally to 17 patients, intramuscularly to three patients, and both o...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1987.67.6.0807
更新日期：1987-12-01 00:00:00
abstract：OBJECT:The authors conducted a study to determine the factors associated with right-sided language dominance in patients with cerebrovascular malformations. METHODS:Twenty-two patients with either arteriovenous malformations (AVMs [15 cases]) or cavernous malformations (7 cases) underwent functional MR (fMR) imaging s...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2010.2.JNS091595
更新日期：2010-10-01 00:00:00
abstract：:The authors report on the morphological features of a pituitary adenoma that produced growth hormone (GH) and adrenocorticotropic hormone (ACTH). This hormone combination produced by a single adenoma is extremely rare; a review of the available literature showed that only one previous case has been published. The tumo...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/jns.1998.88.6.1111
更新日期：1998-06-01 00:00:00
abstract：:Because it has been difficult to predict the outcome of patients with head injury in the early period after admission, a clinical study was undertaken to evaluate if the fibrinolytic parameters could be reliable indicators of outcome. Seventy patients presenting with head injury without obvious trauma in other regions...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1997.86.5.0768
更新日期：1997-05-01 00:00:00
abstract：OBJECT:The authors performed a study to review outcomes following Gamma Knife radiosurgery for cerebral arteriovenous malformations (AVMs) and to create a practical scale to predict long-term outcome. METHODS:Outcomes were reviewed in 1012 patients who were followed up for more than 2 years. Favorable outcome was defi...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2013.5.JNS1311
更新日期：2013-10-01 00:00:00
abstract：OBJECT:The authors performed an analysis of retrospectively obtained data to compare the outcomes of pediatric patients admitted to their institution for traumatic injuries resulting from car, motorcycle, and all-terrain vehicle (ATV) accidents. METHODS:The authors conducted a retrospective review of Columbus Children...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/ped.2006.105.3.182
更新日期：2006-09-01 00:00:00
abstract：OBJECT:The aim of this study was to assess the incidence and outcome of procedure-related rupture of intracranial aneurysms in patients treated with Guglielmi detachable coils (GDCs) and to identify risk factors for this complication. METHODS:Procedure-related rupture occurred in seven of 264 treated aneurysms in 239 ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2001.94.2.0238
更新日期：2001-02-01 00:00:00
abstract：OBJECTIVE:The authors conducted a pilot study on hybrid fluorescein-guided surgery for pituitary adenoma resection and herein describe the feasibility and safety of this technique. METHODS:In this pilot study, the authors included all consecutive patients presenting with pituitary adenomas, functioning and nonfunction...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2019.1.JNS181512
更新日期：2019-04-05 00:00:00
abstract：:The President of the American Association of Neurological Surgeons (AANS) reviews the formative history of the major neurosurgical societies, together with their agreement to consolidate their efforts in the joint AANS. As a united group, the Association has been effective in carrying out relations with other professi...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1979.51.4.0429
更新日期：1979-10-01 00:00:00
abstract：:Myositis ossificans (MO) is a disorder characterized by the intramuscular proliferation of fibroblasts and osteoblasts, with subsequent deposition of bone and cartilage. A typical clinical presentation involves traumatic injury to a young adult, usually localized to the thigh, buttock, or upper arm, with resultant MO ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2001.95.3.0525
更新日期：2001-09-01 00:00:00
abstract：Objective:The authors previously described a graded approach to skull base repair following endonasal microscopic or endoscope-assisted tumor surgery. In this paper they review their experience with skull base reconstruction in the endoscopic era. Methods:A retrospective review of a single-institution endonasal endosc...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2017.11.JNS172141
更新日期：2018-05-11 00:00:00
abstract：:This 61-year-old man with a right-sided tentorial dural arteriovenous fistula (DAVF) was initially treated with staged stereotactic radiosurgery and transarterial embolization. Results of follow-up cerebral angiography performed 4 years later demonstrated complete obliteration of the dAVF and development of a previous...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2000.93.6.1058
更新日期：2000-12-01 00:00:00
abstract：:Gadolinium-diethylenetriaminepenta-acetic acid (Gd-DTPA) is a chelated paramagnetic contrast agent under clinical trial for use in magnetic resonance (MR) imaging. The increased signal intensity following the intravenous infusion of contrast medium may improve the ability of MR imaging to delineate tumors. The use of ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1989.71.1.0049
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVE:Orbital tumors are often surgically challenging because they require an extensive fronto-temporo-orbital zygomatic approach (FTOZ) and a multidisciplinary team approach to provide the best outcomes. Recently, minimally invasive endoscopic techniques via a transorbital superior eyelid approach (ETOA) or endosc...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2020.6.JNS20890
更新日期：2020-09-25 00:00:00
abstract：:Endodermal sinus tumor (yolk sac carcinoma), a germinal neoplasm, is rarely primary in the cranial cavity. The authors add a third case with the tumor located in the anterior third ventricular (suprasellar) region to the literature. Seventeen previously reported intracranial cases, mostly in the pineal region, are bri...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1979.50.2.0246
更新日期：1979-02-01 00:00:00
abstract：:Ischemic stroke remains a leading cause of morbidity and death for which few therapeutic options are available. The development of neuroprotective agents, a once promising field of investigation, has failed to translate from bench to bedside successfully. This work reviews the ischemic cascade, agents targeting steps ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/2012.11.JNS12408
更新日期：2013-05-01 00:00:00
abstract：OBJECT:The aim of the study was to assess retrospectively the clinical efficacy and possible adverse effects of electrical spinal cord stimulation (SCS) for the treatment of patients with reflex sympathetic dystrophy (RSD). METHODS:Twenty-three patients who suffered severe pain due to RSD were included in the study. T...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/spi.1999.90.1.0079
更新日期：1999-01-01 00:00:00
abstract：OBJECT:Guglielmi detachable coil (GDC) technology is a valuable therapeutic alternative to the surgical treatment of ruptured or incidental intracranial aneurysms. The authors describe their technical and clinical experience in the use of the GDC technique in patients who underwent endovascular occlusion for the treatm...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1999.90.2.0207
更新日期：1999-02-01 00:00:00
