Base deficit is superior to lactate in trauma.

Abstract:

BACKGROUND:Base Deficit (BD) and lactate have been used as indicators of shock and resuscitation. This study was done to determine the association of BD and lactate and to determine if one is superior. METHODS:A retrospective review from 3/2014-12/2016 was performed. Data included demographics, systolic BP, ISS, BD, lactate, blood transfusion, and outcomes. BD and lactate were modeled continuously and categorically and compared. RESULTS:1191 patients were included. BD and lactate correlated strongly (r = -0.76 p < 0.001). Higher lactate and more negative BD were associated with transfusion and mortality. On multivariate regression, only BD was associated with transfusion (OR = 0.8, p < 0.001). As a categorical variable, worsening BD was associated with decreased BP, higher ISS, increased transfusions and worse outcomes. CONCLUSIONS:BD and lactate are strongly related. BD was superior to lactate in assessing the need for transfusion. The BD categories discriminate high risk trauma patients better than lactate.

journal_name

Am J Surg

authors

Davis JW,Dirks RC,Kaups KL,Tran P

doi

10.1016/j.amjsurg.2018.01.025

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

682-685

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(17)30545-7

journal_volume

215

pub_type

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