Abstract:
:This corrects the article DOI: 10.1038/leu.2017.9.
journal_name
Leukemiajournal_title
Leukemiaauthors
Schütz C,Inselmann S,Saussele S,Dietz CT,Müller MC,Eigendorff E,Brendel CA,Metzelder SK,Brümmendorf TH,Waller C,Dengler J,Goebeler ME,Herbst R,Freunek G,Hanzel S,Illmer T,Wang Y,Lange T,Finkernagel F,Hehlmann R,Hudoi
10.1038/leu.2017.348subject
Has Abstractpub_date
2018-04-01 00:00:00pages
1054issue
4eissn
0887-6924issn
1476-5551pii
leu2017348journal_volume
32pub_type
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abstract::In this study we have analyzed the chromosomal changes in the preleukemic phase in SJL/J mice treated with radiation and acute myeloid leukemias (AMLs) induced by radiation alone or with additional corticosteroid treatment. SJL/J mice exposed to 300 rad whole body irradiation developed a low incidence of AML (20-25%) ...
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abstract::A murine megakaryoblastic cell line growing in protein-free culture (L8057Y5) was established from an experimentally induced murine leukemia (MK8057). Most of the Y5 cells were small and blast-like, with 2-4N in DNA content. Also, large cells possessing a lobulated nucleus characteristic of megakaryocytes, which showe...
journal_title:Leukemia
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journal_title:Leukemia
pub_type: 杂志文章
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journal_title:Leukemia
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abstract::The INK4A/ARF locus yields two tumor suppressors, p16INK4A and p14ARF, and is frequently deleted in human tumors. We studied their mRNA expressions in 41 hematopoietic cell lines and in 137 patients with hematological malignancies; we used a quantitative reverse transcription-PCR assay. Normal peripheral bloods, bone ...
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journal_title:Leukemia
pub_type: 杂志文章
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journal_title:Leukemia
pub_type: 杂志文章,评审
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journal_title:Leukemia
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doi:10.1038/sj.leu.2402465
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abstract::Human T cell leukemia virus type-I (HTLV-I), the etiologic agent of adult T cell leukemia (ATL) transforms human T cells in vitro and in vivo. Tax, the major transactivator of HTLV-I is critical for the initial events involved in transformation, however, the later steps required for progression from an IL-2 dependent ...
journal_title:Leukemia
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
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journal_title:Leukemia
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::Therapy-related myelodysplastic syndrome and acute myelogenous leukemia (t-MDS/AML) are serious complications of chemotherapy and radiotherapy for cancer. High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) may be associated with an increased incidence of these complications. The frequency o...
journal_title:Leukemia
pub_type: 杂志文章
doi:10.1038/sj.leu.2402631
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journal_title:Leukemia
pub_type: 杂志文章
doi:
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abstract::By combining the polymerase chain reaction and differential library screening, a cDNA for an mRNA expressed in chicken avian myeloblastosis virus (AMV)-transformed monoblasts was isolated. This mRNA is not expressed in erythroblast or T-lymphoblast cell lines. Induced differentiation of the cells of the AMV-transforme...
journal_title:Leukemia
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journal_title:Leukemia
pub_type: 杂志文章
doi:10.1038/leu.2008.234
更新日期:2008-12-01 00:00:00
abstract::ATP-binding-cassette (ABC) transporters are evolutionary extremely well-conserved transmembrane proteins that are highly expressed in hematopoietic stem cells (HSCs). The physiological function in human stem cells is believed to be protection against genetic damage caused by both environmental and naturally occurring ...
journal_title:Leukemia
pub_type: 杂志文章,评审
doi:10.1038/sj.leu.2404859
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