cDNA cloning of a homeobox-containing gene expressed in avian myeloblastic virus-transformed chicken monoblastic leukaemia cells.

Abstract:

:By combining the polymerase chain reaction and differential library screening, a cDNA for an mRNA expressed in chicken avian myeloblastosis virus (AMV)-transformed monoblasts was isolated. This mRNA is not expressed in erythroblast or T-lymphoblast cell lines. Induced differentiation of the cells of the AMV-transformed BM2 line was associated with reduced levels of this transcript. The predicted protein product of Chox M was a homeodomain factor similar to murine Hox-4.3.

journal_name

Leukemia

journal_title

Leukemia

authors

Crompton MR,MacGregor AD,Goodwin GH

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

357-60

issue

5

eissn

0887-6924

issn

1476-5551

journal_volume

5

pub_type

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