Abstract：
OBJECTIVE:To evaluate the effect of important trials on the practice of neurosurgery. METHODS:We hypothesized that evidence from trials addressing the management of intracranial aneurysms (International Subarachnoid Aneurysm Trial [ISAT]) and nontraumatic intracerebral hemorrhages (Surgical Trial in Intracerebral Hemorrhage [STICH]) and vertebral augmentation for osteoporotic vertebral body fractures had a significant impact on the frequency of the corresponding neurosurgical procedures. A Medicare administrative database was queried for corresponding Common Procedural Terminology codes and units billed per calendar year. The effects of ISAT and STICH were evaluated using a generalized linear model. The effect of the vertebral augmentation study was evaluated using a t test. RESULTS:After publication of ISAT in 2002, the rate of increase in proportion of cerebral aneurysms that were treated with embolization (Common Procedural Terminology code 61624) per year increased from 3.9% to 5.5% (P = 0.01). After publication of STICH in 2005, the number of craniotomies performed for intracerebral hematoma decreased from 2341 in 2002 to 1646 in 2011 (P = 0.03). After 2 publications in 2009, performance of vertebral augmentation decreased from a high of 99,961 in 2009 per year to 77,108 in 2013 (P = 0.002). CONCLUSIONS:Randomized clinical trials remain the gold standard in the medical community to demonstrate efficacy, but their true impact relies on rapid and extensive assimilation into everyday medical practice. However, the described methodology establishes a temporal relationship only and does not prove causation. Nonetheless, trends in procedural volume suggest that the results of these select randomized clinical trials had a significant effect on neurosurgical practice affecting Medicare patients within an interval of a few years.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Simon SD,Koyama T,Zacharia BE,Schirmer CM,Cheng JSdoi
10.1016/j.wneu.2015.01.011subject
Has Abstractpub_date
2015-04-01 00:00:00pages
431-7issue
4eissn
1878-8750issn
1878-8769pii
S1878-8750(15)00033-9journal_volume
83pub_type
杂志文章abstract：BACKGROUND:The Timed Up and Go (TUG) test, as a measure of objective functional impairment in lumbar degenerative disk disease (DDD), complements patient-reported outcome measures (PROMs) of subjective functional impairment. METHODS:Prospective 2-center study on consecutive patients scheduled for surgical treatment fo...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2016.11.039
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:Postoperative infection is a potentially dramatic consequence in endoscopic endonasal surgery. The aim of this study was to assess the efficacy of our intraoperative antibiotic prophylaxis by analyzing the risk factors of postoperative meningitis in our series. METHODS:Each endoscopic endonasal procedure per...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.07.075
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journal_title：World neurosurgery
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.03.035
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:Surgical robotics present new and unique opportunities for the training and practice of neurosurgery, beyond the promise of the minimally invasive paradigm. METHODS:Robotic systems have been developed that simulate the sight, sound, and touch of surgery allowing surgical training to evolve past an apprentice...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.04.005
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:The present study evaluated the relationships among perioperative hyperchloremic metabolic acidosis (HCA), hyperchloremia, and postoperative acute kidney injury (AKI) in patients who had undergone craniotomy for intracranial hemorrhage (ICH). METHODS:The present retrospective cohort study included adult pat...
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doi：10.1016/j.wneu.2019.02.015
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:Stereotactic radiosurgery (SRS) as a treatment for cerebral cavernous malformation (CCM) has been controversial, but there are few pathological reports showing its long-term therapeutic effect, and literature reporting the CCM cyst formation after SRS is also rare. CASE DESCRIPTION:We present a 30-year-old ...
journal_title：World neurosurgery
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.064
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:The benefit of prophylactic antibiotic use in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary lesions is controversial. Many surgeons administer antibiotics perioperatively not based on clear guidelines but to be safe. The purpose of this study was to determine if antibiotic prophylaxis use...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.082
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journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
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更新日期：2016-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
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journal_title：World neurosurgery
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journal_title：World neurosurgery
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更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Meningiomas are more prevalent with increasing age, and there is no general consensus of surgical management for this group of tumors. The role of resection and the predictors of recurrence of meningiomas in elderly patients have not been well established. The authors reviewed their experience of surgical re...
journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2016-06-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Isolated hypoglossal nerve palsy caused by an atlantooccipital synovial cyst is a rare lesion, with fewer than 5 cases reported in the literature. CASE DESCRIPTION:Our patient presented with acute hypoglossal nerve dysfunction. Our differential included neoplasm, trauma, stroke, multiple sclerosis, or other...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2019-06-01 00:00:00
abstract：:Terminal myelocystocele is a rare type of neural tube malformation, consisting of a skin-covered lumbosacral mass, highly associated with other complex abdominal malformations within the OIES complex (omphalocele, imperforate anus, exstrophy of the cloaca and spinal defects). We present a case of a premature female wi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.11.135
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.05.130
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journal_title：World neurosurgery
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.05.045
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Successful resection of arteriovenous malformation (AVM) depends on preoperative assessment of the detailed morphology of the AVM. Simultaneous detailed three-dimensional visualization of the feeding arteries, draining veins, and surrounding structures is needed. The aim of this study was to evaluate the use...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.12.217
更新日期：2019-01-22 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.11.051
更新日期：2016-04-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.03.068
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:The Pipeline Embolization Device (PED) has been increasingly used for the treatment of posterior circulation aneurysms. The purpose of the present study was to examine the clinical and angiographic outcomes of patients with vertebrobasilar aneurysms treated with the PED. METHODS:We performed a retrospective...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.12.116
更新日期：2019-01-03 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2012.09.006
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:For multisession radiosurgery, no published data relate the volume and dose of cochlear irradiation to quantified risk of hearing loss. We conducted a retrospective, dosimetric study to evaluate the relationship between hearing loss after stereotactic radiosurgery (SRS) and the dose-volume of irradiated cochl...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2012.04.001
更新日期：2013-09-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.12.029
更新日期：2017-03-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.wneu.2018.06.005
更新日期：2018-09-01 00:00:00
