A Primary Pigmented Choroid Plexus Papilloma Located Within the Sella Turcica: Case Report and Literature Review.

Abstract:

BACKGROUND:Choroid plexus papillomas (CPPs) are rare benign tumors, and the pigmented subtype is observed even more rarely. CASE DESCRIPTION:We present the case of a 43-year-old woman with complaints of headache and progressive left monocular visual deterioration, whose initial plain computed tomography CT scan showed an ovate high-density tumor located within the insellar region. Magnetic resonance imaging revealed a homogeneously contrast-enhancing tumor extending from the sella turcica to the suprasellar cistern. Single-nostril transsphenoidal endoscopic resection followed by subfrontal subtotal resection was performed in this patient. Postoperative histology revealed that the tumor consisted of hyperchromatic tissue with papillary features. Higher-resolution examination of the tissue revealed this tissue was composed of hyperplastic columnar epithelial cells with hyperchromatic cytoplasmic pigment. Subsequent immunohistochemistry identified the lesion as a pigmented choroid plexus papilloma. Here we review the current literature, discuss the origin of the tumor, the differential diagnosis, and the roles of surgery and radiotherapy. CONCLUSIONS:This case study provides important clinical information for the evaluation, diagnosis, and treatment of pigmented CPP in the sellar region.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Gong X,Liu C,Zhang L,Li Z,Bartley CM,Liu Z

doi

10.1016/j.wneu.2017.06.155

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

1039.e13-1039.e18

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(17)31052-5

journal_volume

105

pub_type

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