Abstract:
:Transcranial direct current stimulation (tDCS) has been reported to improve working memory (WM) performance in healthy individuals, suggesting its value as a means of cognitive enhancement. However, recent meta-analyses concluded that tDCS has little or no effect on WM in healthy participants. In this article, we review reasons why these meta-analyses may have underestimated the effect of tDCS on WM and report a more comprehensive and arguably more sensitive meta-analysis. Consistent with our interest in enhancement, we focused on anodal stimulation. Thirty-one articles matched inclusion criteria and were included in four primary meta-analyses assessing the WM effects of anodal stimulation over the left and right dorsolateral pFC (DLPFC) and right parietal lobe as well as left DLPFC stimulation coupled with WM training. These analyses revealed a small but significant effect of left DLPFC stimulation coupled with WM training. Left DLPFC stimulation alone also enhanced WM performance, but the effect was reduced to nonsignificance after correction for publication bias. No other effects were significant, including a variety of tested moderators. Additional meta-analyses were undertaken with study selection criteria based on previous meta-analyses, to reassess the findings from these studies using the analytic methods of this study. These analyses revealed a mix of significant and nonsignificant small effects. We conclude that the primary WM enhancement potential of tDCS probably lies in its use during training.
journal_name
J Cogn Neuroscijournal_title
Journal of cognitive neuroscienceauthors
Mancuso LE,Ilieva IP,Hamilton RH,Farah MJdoi
10.1162/jocn_a_00956subject
Has Abstractpub_date
2016-08-01 00:00:00pages
1063-89issue
8eissn
0898-929Xissn
1530-8898journal_volume
28pub_type
杂志文章,meta分析,评审abstract::The majority of the research related to visual recognition has so far focused on bottom-up analysis, where the input is processed in a cascade of cortical regions that analyze increasingly complex information. Gradually more studies emphasize the role of top-down facilitation in cortical analysis, but it remains somet...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章,评审
doi:10.1162/089892903321662976
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abstract::Young and older adults are more likely to remember emotional information than neutral information. The present functional magnetic resonance imaging study examined the neural processes supporting young (ages 18-35) and older (ages 62-79) adults' successful encoding of positive, negative, and neutral objects (e.g., a s...
journal_title:Journal of cognitive neuroscience
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journal_title:Journal of cognitive neuroscience
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journal_title:Journal of cognitive neuroscience
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journal_title:Journal of cognitive neuroscience
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更新日期:2018-03-01 00:00:00
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journal_title:Journal of cognitive neuroscience
pub_type: 临床试验,杂志文章
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journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1997.9.1.67
更新日期:1997-01-01 00:00:00
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journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892904970744
更新日期:2004-06-01 00:00:00
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journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00602
更新日期:2014-09-01 00:00:00
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journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00009
更新日期:2011-10-01 00:00:00
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journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2009.21304
更新日期:2010-08-01 00:00:00
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journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1996.8.6.481
更新日期:1996-11-01 00:00:00
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journal_title:Journal of cognitive neuroscience
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doi:10.1162/jocn_a_01535
更新日期:2020-06-01 00:00:00
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journal_title:Journal of cognitive neuroscience
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doi:10.1162/jocn.2006.18.7.1174
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journal_title:Journal of cognitive neuroscience
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doi:10.1162/jocn_a_00190
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journal_title:Journal of cognitive neuroscience
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doi:10.1162/jocn.2009.21244
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journal_title:Journal of cognitive neuroscience
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journal_title:Journal of cognitive neuroscience
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更新日期:2005-10-01 00:00:00
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journal_title:Journal of cognitive neuroscience
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