Abstract:
:In this review, the loading efficacies of retinoids with milk proteins are investigated. It has been shown that milk proteins β-lactoglobulin, α-, and β-caseins bind retinol and retinoic acid via hydrophobic, hydrophilic, and H-bonding contacts causing minor alterations of protein secondary structure. Hydrophobic contact is predominant in retinoid-protein conjugation and several amino acids are involved in complex formation, stabilized by H-bonding network. Loading efficacy of retinoid was about 30-50% with retinol forming more stable protein conjugates. Milk proteins can transport retinoid to target molecules.
journal_name
J Biomol Struct Dynjournal_title
Journal of biomolecular structure & dynamicsauthors
Agudelo D,Bourassa P,Bariyanga J,Tajmir-Riahi HAdoi
10.1080/07391102.2017.1411833subject
Has Abstractpub_date
2018-12-01 00:00:00pages
4246-4254issue
16eissn
0739-1102issn
1538-0254journal_volume
36pub_type
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