Science to Practice: Can Functional MR Imaging Be Useful in the Evaluation of Cardiorenal Syndrome?

Abstract:

:Functional magnetic resonance (MR) imaging of the kidneys has gained interest recently, especially in the detection of early changes in acute kidney injury or to predict progression of chronic kidney disease (CKD). The application of these methods to cardiorenal syndrome (CRS) is novel. CRS is widely accepted as a complex clinical problem routinely faced by clinicians. In this issue, Chang et al ( 1 ) present their preliminary experience applying blood oxygen level-dependent (BOLD) MR imaging to the kidneys in mice with experimental myocardial infarction. They showed that R2* in the kidney increases after induced myocardial infarction and that the response was higher in animals with larger infarcts and over time. The authors also for the first time correlated the BOLD MR imaging findings against hypoxia-inducible factor-1α (HIF-1α) expression, an independent marker of renal hypoxia. In addition, they showed evidence for renal injury by using a kidney injury marker, kidney injury molecule-1 (KIM-1). The results of their study support the use of renal BOLD MR imaging in subjects with heart failure, in whom the risk of subsequent renal ischemia and/or hypoxia is known to exist. These results, along with those of other recent reports ( 2 ), suggest that functional imaging methods could play a key role in evaluating changes in both the primary and secondary organs involved in complex disease processes such as CRS. Availability of such methods could facilitate translation to the clinic and improve the mechanistic understanding of the complicated and interrelated pathophysiology.

journal_name

Radiology

journal_title

Radiology

authors

Pursnani A,Prasad PV

doi

10.1148/radiol.2017171957

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

1-3

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

286

pub_type

评论,杂志文章
  • Pelvimetry by digital radiography: a low-dose examination.

    abstract::Digital radiographs obtained with a CT scanner were evaluated as an alternative to conventional pelvimetry. Dosimetry studies demonstrated an absorbed radiation dose of 22 mrad for each digital radiograph, approximately 3% of the dose for comparable standard radiographs. Distance measurements were accurately made on d...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.143.3.7079500

    authors: Federle MP,Cohen HA,Rosenwein MF,Brant-Zawadzki MN,Cann CE

    更新日期:1982-06-01 00:00:00

  • Utilization of radiologic services in different payment systems and patient populations.

    abstract:PURPOSE:To report population-based utilization rates and their variability across and within populations, geographic areas, and different payment systems for diagnostic radiology and radiation oncology procedures. MATERIALS AND METHODS:Aggregated claims data were obtained from four sources for up to nine radiologic mo...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.200.1.8657910

    authors: Burkhardt JH,Sunshine JH

    更新日期:1996-07-01 00:00:00

  • Acute pulmonary embolism: ancillary findings at spiral CT.

    abstract:PURPOSE:To determine the value of parenchymal findings at contrast material-enhanced spiral computed tomography (CT) in patients suspected to have pulmonary embolism (PE). MATERIALS AND METHODS:Eighty-eight patients suspected to have PE underwent contrast-enhanced spiral CT and ventilation-perfusion scintigraphy. Conc...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.207.3.9609900

    authors: Coche EE,Müller NL,Kim KI,Wiggs BR,Mayo JR

    更新日期:1998-06-01 00:00:00

  • Solitary pulmonary opacities: plain tomography.

    abstract::New or enlarging solitary pulmonary opacities in 502 patients were evaluated with a plain tomographic procedure. Repeat chest radiographs in 64 patients and tomograms in 115 patients showed that the opacities were not nodules but were due to pneumonitis, rib lesions, thickened pleura, or another benign finding. Tomogr...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.163.2.3562830

    authors: Huston J 3rd,Muhm JR

    更新日期:1987-05-01 00:00:00

  • Spermatic vein embolization with hot contrast material: fertility results.

    abstract::Spermatic venography with hot contrast material embolization was undertaken in 81 patients with varicoceles and infertility. Long-term follow-up information was available in 91% of the patients, and there was an overall conception rate of 40.5%. Embolization with hot contrast material was easily performed without spec...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.168.1.3380950

    authors: Smith TP,Hunter DW,Cragg AH,Darcy MD,Castaneda-Zuniga WR,Sinclair TR,Ercole C,Hulbert JC,Kaye KW,Amplatz K

    更新日期:1988-07-01 00:00:00

  • Thin-section CT of the lung: does electrocardiographic triggering influence diagnosis?

    abstract:PURPOSE:To determine the impact of prospective electrocardiographic (ECG) triggering on image quality and diagnostic outcome of thin-section computed tomography (CT) of the lung. MATERIALS AND METHODS:Forty-five consecutive patients referred for thin-section CT of the lung were examined with prospectively ECG-triggere...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2292021114

    authors: Boehm T,Willmann JK,Hilfiker PR,Weishaupt D,Seifert B,Crook DW,Marincek B,Wildermuth S

    更新日期:2003-11-01 00:00:00

  • The use of ROC curves in testing the proficiency of individuals in classifying pneumoconiosis.

    abstract::During a test of the ability to classify the profusion characteristics of pneumoconiosis recorded in chest radiographs, a constant decision criterion level needs to be maintained or false conclusions regarding the observer's receiver operating characteristic (ROC) curve may result. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/114.2.472

    authors: Goodenough DJ

    更新日期:1975-02-01 00:00:00

  • Adenoma malignum: MR imaging and pathologic study.

    abstract:PURPOSE:To evaluate the clinical, pathologic, and magnetic resonance (MR) imaging findings in adenoma malignum, a rare variant of uterine cervical adenocarcinoma. MATERIALS AND METHODS:Medical records of all patients (n = 7) with adenoma malignum of the uterine cervix diagnosed pathologically between 1988 and 1996 wer...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.204.1.9205220

    authors: Doi T,Yamashita Y,Yasunaga T,Fujiyoshi K,Tsunawaki A,Takahashi M,Katabuchi H,Tanaka N,Okamura H

    更新日期:1997-07-01 00:00:00

  • Aggressive neuroblastoma simulating Wilms tumor.

    abstract::Solid intrarenal neoplasms in children are usually Wilms tumors. Occasionally, however, a neuroblastoma appears to be intrarenal. In six cases where this phenomenon was observed, the histologic findings of each tumor were identical: undifferentiated neuroblastoma. In each case the child's condition rapidly and progres...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.166.1.2827230

    authors: Rosenfield NS,Leonidas JC,Barwick KW

    更新日期:1988-01-01 00:00:00

  • Participation of the external and internal carotid arteries in the blood supply of acoustic neurinomas.

    abstract::Six cases of acoustic neurinoma are presented in which the tumor is supplied by branches of the external carotid artery, with or without supply from the internal carotid artery. A new angiographic protocol for the investigation of masses in the cerebellopontine angle is suggested. According to early results of the CT ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/118.1.83

    authors: Théron J,Lasjaunias P

    更新日期:1976-01-01 00:00:00

  • Reciprocating Bucky for serial film changers.

    abstract::A reciprocating Bucky design for serial film changers is described. It is simple to construct. Inexpensive, and enhances radiograph resolution by eliminating grid lines. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/125.1.250

    authors: Becker JA,Heiferman S

    更新日期:1977-10-01 00:00:00

  • US depiction of partial-thickness tear of the rotator cuff.

    abstract:PURPOSE:To test previously defined ultrasound (US) criteria for identification of partial-thickness tears of the rotator cuff. MATERIALS AND METHODS:Before shoulder arthroscopy, 52 patients with shoulder pain for more than 3 months were examined with a 7.5-MHz commercially available linear-array transducer and a stand...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.197.2.7480690

    authors: van Holsbeeck MT,Kolowich PA,Eyler WR,Craig JG,Shirazi KK,Habra GK,Vanderschueren GM,Bouffard JA

    更新日期:1995-11-01 00:00:00

  • Obstructive jaundice caused by polycystic liver disease.

    abstract::A patient with jaundice caused by obstruction of the biliary ducts by cysts in a polycystic liver is presented. Decompression of the liver cysts under ultrasound guidance resulted in a rapid decrease of the serum bilirubin level. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.136.2.7403520

    authors: Ergün H,Wolf BH,Hissong SL

    更新日期:1980-08-01 00:00:00

  • Common bile duct calculi: updated experience with dissolution with methyl tertiary butyl ether.

    abstract::The authors describe their experience with methyl tertiary butyl ether (MTBE) in a larger series of patients than previously reported in order to acquaint physicians with both its effectiveness for dissolution of common bile duct calculi and the limitations of its use. Ten patients with 13 biliary calculi underwent pe...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.166.3.3340760

    authors: Brandon JC,Teplick SK,Haskin PH,Sammon JK,Muhr WF,Hofmann AF,Gambescia RA,Zitomer N

    更新日期:1988-03-01 00:00:00

  • Imaging and intervention in acute pancreatitis.

    abstract::An International Symposium was held in Atlanta in 1992 to present the state of the art of diagnostic evaluation and management of acute pancreatitis and to agree on an acceptable series of clinical definitions for classifying the disease and its complications. The symposium was composed of 40 internationally recognize...

    journal_title:Radiology

    pub_type: 杂志文章,评审

    doi:10.1148/radiology.193.2.7972730

    authors: Balthazar EJ,Freeny PC,vanSonnenberg E

    更新日期:1994-11-01 00:00:00

  • Redefinitions of indications for percutaneous nephrostomy.

    abstract::An analysis of treatment response in 215 patients treated by percutaneous nephrostomy identified obstruction of the urinary tract, complicated by infection and sometimes gram-negative septicemia, as the single most important indication for this intervention. Percutaneous nephrostomy reduced the mortality from gram-neg...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.147.2.6836120

    authors: Lang EK,Price ET

    更新日期:1983-05-01 00:00:00

  • Pulmonary embolus: detection and follow-up using magnetic resonance.

    abstract::Magnetic resonance imaging (MRI) of an angiographically confirmed pulmonary embolus was performed. The thrombus appeared as an intense intraluminal signal within the left descending pulmonary artery; this signal was absent on repeat examination after clot lysis. Because MR will not image flowing blood, it provides a p...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.153.2.6484180

    authors: Moore EH,Gamsu G,Webb WR,Stulbarg MS

    更新日期:1984-11-01 00:00:00

  • Assessment of acute renal transplant rejection with blood oxygen level-dependent MR imaging: initial experience.

    abstract:PURPOSE:To prospectively assess the oxygenation state of renal transplants and determine the feasibility of using blood oxygen level-dependent (BOLD) magnetic resonance (MR) imaging to differentiate between acute tubular necrosis (ATN), acute rejection, and normal function. MATERIALS AND METHODS:This HIPAA-compliant s...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2363041080

    authors: Sadowski EA,Fain SB,Alford SK,Korosec FR,Fine J,Muehrer R,Djamali A,Hofmann RM,Becker BN,Grist TM

    更新日期:2005-09-01 00:00:00

  • The effect of fasting on gallbladder opacification during oral cholecystography: a controlled study in normal volunteers.

    abstract::The effect of fasting on gallbladder opacification during oral cholecystography was studied in 10 normal volunteers using 2 oral cholecystographic agents, iopanoic acid and sodium tryopanoate. Radiographs made 15 hours after ingestion of the contrast agents revealed good opacification of the gallbladder in all subject...

    journal_title:Radiology

    pub_type: 临床试验,杂志文章

    doi:10.1148/126.2.395

    authors: Loeb PM,Berk RN,Janes JO,Perkin L,Moore J

    更新日期:1978-02-01 00:00:00

  • Peripheral vascular disease: blinded study of dedicated calf MR angiography versus standard bolus-chase MR angiography and film hard-copy angiography.

    abstract:PURPOSE:To compare the accuracy of contrast material-enhanced three-dimensional (3D) dedicated calf magnetic resonance (MR) angiography with that of bolus-chase MR angiography, with conventional angiography as the reference standard, in patients with symptomatic peripheral vascular disease (PVD). MATERIALS AND METHODS...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2323030244

    authors: Binkert CA,Baker PD,Petersen BD,Szumowski J,Kaufman JA

    更新日期:2004-09-01 00:00:00

  • Depiction of transplant renal vascular anatomy and complications: unenhanced MR angiography by using spatial labeling with multiple inversion pulses.

    abstract:PURPOSE:To evaluate the ability to depict anatomy and complications of renal vascular transplant with unenhanced magnetic resonance (MR) angiography with spatial labeling with multiple inversion pulses (SLEEK) and to compare the results with color Doppler (CD) ultrasonography (US), digital subtraction angiography (DSA)...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.14131800

    authors: Tang H,Wang Z,Wang L,Hu X,Wang Q,Li Z,Li J,Meng X,Wang Y,Hu D

    更新日期:2014-06-01 00:00:00

  • Optimal scan parameters for CT fluoroscopy in lung interventional radiologic procedures: relationship between radiation dose and image quality.

    abstract:PURPOSE:To evaluate the relationship between radiation doses and lung computed tomographic (CT) fluoroscopic scan parameters and to determine optimal scan parameters for performance of lung interventional radiologic (IR) procedures. MATERIALS AND METHODS:The institutional review board approved this prospective study, ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.09090733

    authors: Yamao Y,Yamakado K,Takaki H,Yamada T,Murashima S,Uraki J,Kodama H,Nagasawa N,Takeda K

    更新日期:2010-04-01 00:00:00

  • Pyarthrosis complicating rheumatoid arthritis. Roentgenographic evaluation of 5 patients and review of the literature.

    abstract::Five patients with pyarthrosis complicating rheumatoid arthritis are described. Only minimal clinical signs may be seen in such patients, making accurate diagnosis of this occasional complication difficult. Roentgenographic abnormalities include a rapidly enlarging joint effusion and progressive cartilage and bone des...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/114.3.581

    authors: Resnick D

    更新日期:1975-03-01 00:00:00

  • Thyroid Imaging Reporting and Data System (TI-RADS): A User's Guide.

    abstract::In 2017, the Thyroid Imaging Reporting and Data System (TI-RADS) Committee of the American College of Radiology (ACR) published a white paper that presented a new risk-stratification system for classifying thyroid nodules on the basis of their appearance at ultrasonography (US). In ACR TI-RADS, points in five feature ...

    journal_title:Radiology

    pub_type: 杂志文章,评审

    doi:10.1148/radiol.2017171240

    authors: Tessler FN,Middleton WD,Grant EG

    更新日期:2018-04-01 00:00:00

  • Angiographic abnormalities in partial Budd-Chiari syndrome.

    abstract::Partial Budd-Chiari syndrome was produced in 8 monkeys by obstructing 2 or 3 lobar hepatic veins with a rapidly polymerizing plastic. Hepatic angiography done 1-3 months later revealed crowded tortuous arteries and a dense hepatogram in the lobe with venous occlusion. Unobstructed lobes were hypertrophied. Retrograde ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/122.3.629

    authors: Maguire R,Doppman JL

    更新日期:1977-03-01 00:00:00

  • Computed tomography in obstructive jaundice. Part II: The cause of obstruction.

    abstract::The value of computed tomography (CT) in determining the cause of obstructive jaundice in 67 proved cases is described. The presence of stones, the level of obstruction, the relative size of the ringlike structures produced by the dilated bile duct, and the shape of the distal visualized ring have proved to be the mos...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.139.3.7232730

    authors: Pedrosa CS,Casanova R,Lezana AH,Fernandez MC

    更新日期:1981-06-01 00:00:00

  • Intracortical fissuring in osteomyelitis.

    abstract::Cortical fissuring, a well-recognized radiographic sign of osteomyelitis, represents spread of infection through the haversian system with osteoclastic bone resorption. In the proper clinical setting this finding may be recognized before there is other evidence of bone destruction or periosteal reaction. Three cases a...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.141.1.7027310

    authors: Rosen RA,Morehouse HT,Karp HJ,Yu GS

    更新日期:1981-10-01 00:00:00

  • Splenic vein thrombosis after splenectomy: frequency and role of imaging.

    abstract:PURPOSE:To assess the frequency of splenic vein thrombosis (SVT) after splenectomy and its consequences on patient treatment. MATERIALS AND METHODS:A group of 183 consecutive patients who underwent splenectomy were evaluated. Of these patients, 119 underwent postoperative ultrasound (US) or computed tomography. RESUL...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.190.1.8259430

    authors: Petit P,Bret PM,Atri M,Hreno A,Casola G,Gianfelice D

    更新日期:1994-01-01 00:00:00

  • Liver metastases from colorectal carcinoma: detection with continuous CT angiography.

    abstract::A diagnostic approach to assess liver metastases from colorectal carcinoma was prospectively evaluated in 30 patients with and without metastases on the basis of findings at conventional computed tomography (CT). With the technique, termed continuous CT angiography (CCTA), CT data were continuously sampled for 24 seco...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.185.1.1523300

    authors: Oudkerk M,van Ooijen B,Mali SP,Tjiam SL,Schmitz PI,Wiggers T

    更新日期:1992-10-01 00:00:00

  • Emergency room radiography of asthma: an efficacy study.

    abstract::The chest radiographs of asthmatic patients in an emergency room setting over a four-year period were reviewed. A total of 997 radiographs was reviewed; radiographic findings were compared with history and clinical data. In adults 2.2% of the radiographs were abnormal; in children 13%. It is concluded that a chest rad...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.145.1.7122890

    authors: Zieverink SE,Harper AP,Holden RW,Klatte EC,Brittain H

    更新日期:1982-10-01 00:00:00