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Independent Association of Vitamin D With Physical Function in People With Chronic Spinal Cord Injury.

Abstract：

OBJECTIVE:To explore the relation between vitamin D and physical function outcomes in people with spinal cord injury (SCI). DESIGN:Cross-sectional study. SETTING:Rehabilitation institute. PARTICIPANTS:Consecutive patients (N=100; 72 men and 28 women) with chronic SCI admitted to a rehabilitation program. INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:Functional independence in activities of daily living (ADL) and leisure time physical activity (LTPA) were assessed as measures of physical function. RESULTS:Vitamin D deficiency (<20ng/mL) was found in 78 patients: they exhibited a significantly higher body mass index, lower functional independence in ADL, and were engaged in a significantly poorer weekly LTPA. At the linear multiple regression analysis, lower 25-hydroxyvitamin D levels showed significant independent associations with poorer functional independence in ADL (β=.59; 95% confidence interval, .36-.82; P<.0001) and with poorer LTPA (β=2.35; 95% confidence interval, 0.77-3.94; P=.004), after adjustment for other predictors of physical function outcomes selected by univariate analyses. CONCLUSIONS:In people with chronic SCI, a low vitamin D level represents an independent predictor of poor physical function.

journal_name

Arch Phys Med Rehabil

journal_title

Archives of physical medicine and rehabilitation

authors

Barbonetti A,Sperandio A,Micillo A,D'Andrea S,Pacca F,Felzani G,Francavilla S,Francavilla F

doi

10.1016/j.apmr.2016.01.002

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

726-32

issue

5

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(16)00032-0

journal_volume

97

pub_type

杂志文章

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