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Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis.

Abstract：

Introduction:The most common form of systemic amyloidosis is amyloid A induced by a chronic inflammation. In HIV-infected patients, elevated serum amyloid A levels might be associated with chronic inflammation. Patient presentation:A 43-year-old male patient was admitted to hospital with a complaint of papular lesions around his eyes, existing for four months. The patient is receiving antiretroviral therapy. HIV RNA was undetectable, and the CD4 count was 770 cells/mm3. He suffered from a bladder carcinoma for four years. On examination, periocular, perioral and anogenital papules, papular lesions in the meatus of external auditory canal, and intranasal polyps were observed. Management:Microscopic examination of the biopsy material taken from the periocular lesion and then from perianal polyps revealed eosinophilic deposition, and stained positively by Congo red. Serum amyloid A level was negative. Antiretroviral therapy was continued. Conclusion:A rare form of amyloidosis in a patient with HIV and/or AIDS and coinfected with hepatitis B virus (HBV) was presented here with cutaneous and mucosal lesions.

journal_name

South Afr J HIV Med

journal_title

Southern African journal of HIV medicine

authors

Demiraslan H,Deniz K,Doganay M

doi

10.4102/sajhivmed.v18i1.735

subject

Has Abstract

pub_date

2017-08-30 00:00:00

pages

735

issue

1

eissn

1608-9693

issn

2078-6751

pii

HIVMED-18-735

journal_volume

18

pub_type

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