Suppression of pulmonary group B streptococcal proliferation and translocation by surfactants in ventilated near-term newborn rabbits.

abstract：:Injuries continue to be the leading cause of morbidity and mortality for children, adolescents, and young adults aged 1-24 years in industrialized countries in the twenty-first century. In this age group, injuries cause more fatalities than all other causes combined in the United States (U.S.). Importantly, many of th...

journal_title：Pediatric research

authors： Dorney K,Dodington JM,Rees CA,Farrell CA,Hanson HR,Lyons TW,Lee LK,and the Injury Free Coalition for Kids®.

更新日期：2020-01-01 00:00:00

abstract：:Various assay methods for detection of thyroid hormones in human milk were evaluated in recovery and dilution experiments after which the concentrations of thyroxine (T4) and 3,5,3'-triiodothyronine (T3) were measured and compared with those in serum. The effect of breast feeding on pituitary thyroid function of norma...

journal_title：Pediatric research

authors： Mizuta H,Amino N,Ichihara K,Harada T,Nose O,Tanizawa O,Miyai K

更新日期：1983-06-01 00:00:00

abstract：:BackgroundSpecific HLA-DQ genes have been recognized as necessary - but not sufficient - factors for the occurrence of Celiac Disease (CD). Through a meta-analysis, evaluating the distribution of CD-related HLA genotypes in children, we aimed at providing insights for a potential widened screening strategy.MethodsAfte...

journal_title：Pediatric research

authors： De Silvestri A,Capittini C,Poddighe D,Valsecchi C,Marseglia G,Tagliacarne SC,Scotti V,Rebuffi C,Pasi A,Martinetti M,Tinelli C

更新日期：2018-03-01 00:00:00

abstract：:An imbalance in apoptosis or survival of immune cells plays an essential role in the pathophysiology of sepsis. Phagocytosis-induced cell death (PICD) is a common result of the pathogen-host cell interaction mediated by reactive oxygen species (ROS). Neonatal sepsis is frequently characterized by hyperinflammation. Co...

journal_title：Pediatric research

authors： Gille C,Leiber A,Spring B,Kempf VA,Loeffler J,Poets CF,Orlikowsky TW

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Genotyping tests were developed to attenuate the impact of viral resistance. Information about the efficacy in genotype base antiretroviral therapy in children is rare and even more in low- and middle-income countries. METHODS:Sixteen children with antiretroviral therapy (ART) failure and triple-class drug-...

journal_title：Pediatric research

authors： Huerta-García G,Vazquez-Rosales JG,Mata-Marín JA,Peregrino-Bejarano L,Flores-Ruiz E,Solórzano-Santos F

更新日期：2016-07-01 00:00:00

abstract：:Vitamin K deficiency is a relatively common condition in neonates. However, the role of vitamin K in neonatal bone metabolism remains to be determined. Osteocalcin (OC) is the most abundant noncollagenous protein in bone, and is regulated to be gamma-carboxylated by vitamin K. In this study, we measured gamma-carboxyl...

journal_title：Pediatric research

authors： Shimizu N,Shima M,Hirai H,Nakajima S,Nishimura K,Yamaoka K,Okada S

更新日期：2002-11-01 00:00:00

abstract：:The microbiome, of which the bacterial component alone (microbiota), is estimated to include 10 times more cells than human cells of the body, blooms immediately after birth and evolves in composition and complexity throughout childhood. The gut microbiome has a profound impact on gastrointestinal tract development, m...

journal_title：Pediatric research

authors： Unger S,Stintzi A,Shah P,Mack D,O'Connor DL

更新日期：2015-01-01 00:00:00

abstract：:The specific activities of four folate enzymes have been measured in livers from preterm infants (Group 1), full-term infants (Group 2), and from control subjects (Group 3). The four enzymes studied were methylene tetrahydrofolate reductase (EC 1.1.1.68), methionine synthetase (EC 2.1.1.13), methylenetetrahydrofolate ...

journal_title：Pediatric research

authors： Kalnitsky A,Rosenblatt D,Zlotkin S

更新日期：1982-08-01 00:00:00

abstract：:Previously, we have reported marked pulmonary inflammation in infants who develop chronic lung disease of prematurity. We revisited these infants who did not have clinical or laboratory evidence of infection and searched for Ureaplasma urealyticum, group B streptococci, and other microbes by reverse transcription-PCR ...

journal_title：Pediatric research

authors： Kotecha S,Hodge R,Schaber JA,Miralles R,Silverman M,Grant WD

更新日期：2004-01-01 00:00:00

abstract：:The results of prior studies suggest that abnormalities of development and function of the fetal adrenal occur in pregnancies complicated by intrauterine fetal growth retardation (IUGR). In the present investigation, we sought to extend such studies by matching IUGR infants with normally grown infants of women in whom...

journal_title：Pediatric research

authors： Parker CR Jr,Buchina ES,Barefoot TK

更新日期：1994-06-01 00:00:00

abstract：:In view of the suggested relationship between substrate availability, fetal growth and circulating fetal IGF-I concentrations, we investigated the effect of maternal starvation on plasma IGF-I levels in the late gestation ovine fetus. Ten fetuses aged 125-130 d gestation were sampled daily from indwelling arterial cat...

journal_title：Pediatric research

authors： Bassett NS,Oliver MH,Breier BH,Gluckman PD

更新日期：1990-04-01 00:00:00

abstract：:Basal and pentagastrin-stimulated gastric acid secretion was measured in 26 healthy newborn infants on the 1st and 2nd days of life. Basal acid outputs (BAO) on day 1 (0.378 mEq/hr) and day 2 (0.388 mEq/hr) were similar and not significantly different from the maximal acid outputs (MAO) on day 1 (0.413 mEq/hr) and day...

journal_title：Pediatric research

authors： Euler AR,Byrne WJ,Meis PJ,Leake RD,Ament ME

更新日期：1979-01-01 00:00:00

abstract：:LBW infants are at risk of iron deficiency (ID), which is associated with impaired nervous system development and may lead to prolonged auditory brainstem response (ABR) latencies. We hypothesized that iron supplementation shortens ABR latencies in marginally LBW (MLBW, 2000-2500 g) infants. In a randomized, controlle...

journal_title：Pediatric research

authors： Berglund SK,Westrup B,Haraldsson E,Engström B,Domellöf M

更新日期：2011-12-01 00:00:00

abstract：:Increased fetal lung expansion profoundly inhibits surfactant protein gene expression and stimulates cellular proliferation in the fetal lung. Our aim was to determine whether increased expansion of the lung after birth, by the application of a continuous positive airway pressure (CPAP) for 12 h, inhibits surfactant p...

journal_title：Pediatric research

authors： Lines AL,Davey MG,Harding R,Hooper SB

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) has been implicated as a key mechanism in the pathogenesis of liver fibrosis. The miR-200 family has been shown to inhibit EMT. METHODS:Liver fibrosis levels were assessed with Masson's trichrome staining of liver samples obtained from biliary atresia (BA) patient...

journal_title：Pediatric research

authors： Xiao Y,Zhou Y,Chen Y,Zhou K,Wen J,Wang Y,Wang J,Cai W

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Macrosomia and child obesity are growing health-care issues worldwide. The purpose of the study was to evaluate how extremely high or low birth weight affects metabolic markers evaluated in newborn screening. METHODS:The study was register-based and included full-term singletons born in Iceland from 2009 to...

journal_title：Pediatric research

authors： Vidarsdottir H,Thorkelsson T,Halldorsson TI,Bjarnason R,Geirsson RT,Rinaldo P,Franzson L

更新日期：2020-06-29 00:00:00

abstract：:To further assess bile acid transport by the developing rat liver, we compared the rate of efflux of taurocholate from hepatocytes isolated from suckling and mature rat livers. Cell content of taurocholate (nmol/mg cell protein), after preloading with [14C]-radiolabeled plus cold bile acid (5-100 microM) was similar i...

journal_title：Pediatric research

authors： Belknap WM,Zimmer-Nechemias L,Suchy FJ,Balistreri WF

更新日期：1988-04-01 00:00:00

abstract：:An Epstein-Barr virus-transformed B-cell line derived from a patient with severe combined immunodeficiency who died of a lymphoreticular malignancy has been characterized. The line derived from bone marrow cultures and designated DV-1 shows surface and cytoplasmic IgM and staining with fluorescent monoclonal antibodie...

journal_title：Pediatric research

authors： Rosenblatt HM,Lewis DE,Sklar J,Cleary ML,Parikh N,Galili N,Ritz J,Shearer WT

更新日期：1987-04-01 00:00:00

abstract：:Glutaryl-CoA dehydrogenase (GCDH) deficiency is a rare inborn disorder of L-lysine, L-hydroxylysine, and L-tryptophan metabolism complicated by striatal damage during acute encephalopathic crises. Three decades after its description, the natural history and how to treat this disorder are still incompletely understood....

journal_title：Pediatric research

authors： Kölker S,Garbade SF,Greenberg CR,Leonard JV,Saudubray JM,Ribes A,Kalkanoglu HS,Lund AM,Merinero B,Wajner M,Troncoso M,Williams M,Walter JH,Campistol J,Martí-Herrero M,Caswill M,Burlina AB,Lagler F,Maier EM,Schwahn B

更新日期：2006-06-01 00:00:00

abstract：INTRODUCTION:In preterm neonates, peroxides contaminating total parenteral nutrition (TPN) contribute to oxidative stress, which is suspected to be a strong inducer of hepatic complications related to prematurity. Recently, others reported that hexapeptides derived from human milk (HM) exerted free radical-scavenging a...

journal_title：Pediatric research

authors： Miloudi K,Tsopmo A,Friel JK,Rouleau T,Comte B,Lavoie JC

更新日期：2012-06-01 00:00:00

abstract：:Ethanol consumption during pregnancy can cause fetal alcohol syndrome (FAS). Although the exact mechanism is unknown, nutritional alterations caused by ethanol exposure may be an etiologic factor in FAS. The congenital heart defects seen in FAS are similar to those found in vitamin A teratogenesis. Because ethanol ing...

journal_title：Pediatric research

authors： DeJonge MH,Zachman RD

更新日期：1995-04-01 00:00:00

abstract：:The aim of this study was to compare catecholamine concentrations in the fetal umbilical artery cord blood from the offspring of smokers versus the offspring of nonsmokers. Pregnant women who were self-identified as smokers (>/=10 cigarettes per day throughout pregnancy) or nonsmokers were recruited for study particip...

journal_title：Pediatric research

authors： Oncken CA,Henry KM,Campbell WA,Kuhn CM,Slotkin TA,Kranzler HR

更新日期：2003-01-01 00:00:00

abstract：:Catecholamines (CA) are released from and resynthesized in the adrenal medulla in response to stress. In the mature animal, stimulus-secretion-synthesis coupling occurs through transsynaptic (neuronal) activity. In contrast, in the immature animal, before functional adrenal innervation, certain stressors (hypoglycemia...

journal_title：Pediatric research

authors： DeCristofaro JD,LaGamma EF

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Later life metabolic dysfunction is a well-recognized consequence of being born small for gestational age (SGA). This study has applied metabolomics to identify whether there are changes in these pathways in prepubertal short SGA children and aimed to compare the intracellular and extracellular metabolome in...

journal_title：Pediatric research

authors： Murray PG,Butcher I,Dunn WB,Stevens A,Perchard R,Hanson D,Whatmore A,Westwood M,Clayton PE

更新日期：2016-08-01 00:00:00

abstract：:Acute kidney injury (AKI) is common in premature infants and is associated with poor outcomes. Novel biomarkers can detect AKI promptly. Because premature infants are born with underdeveloped kidneys, baseline biomarker values may differ. We describe baseline values of urinary neutrophil gelatinase-associated lipocali...

journal_title：Pediatric research

authors： Askenazi DJ,Koralkar R,Levitan EB,Goldstein SL,Devarajan P,Khandrika S,Mehta RL,Ambalavanan N

更新日期：2011-09-01 00:00:00

abstract：:Small bowel resection decreases brush border membrane (BBM) glucose uptake kinetics. Oral epidermal growth factor (EGF) returns net glucose transport across intact tissue to control levels despite persistence of a defect in BBM glucose uptake. The purpose of this study was to examine the effects of resection and EGF t...

journal_title：Pediatric research

authors： Chung BM,Wallace LE,Winkfein RK,O'Loughlin EV,Hardin JA,Gall DG

更新日期：2004-01-01 00:00:00

abstract：:Diabetes mellitus is characterized by microangiopathy and increased angiogenic response in various organs. Basic fibroblast growth factor (bFGF) as well as vascular endothelial growth factor (VEGF) are both angiogenic and are involved in vascular endothelial cell growth. The purpose of this study was to determine seru...

journal_title：Pediatric research

authors： Malamitsi-Puchner A,Sarandakou A,Tziotis J,Dafogianni C,Bartsocas CS

更新日期：1998-12-01 00:00:00

abstract：:The treatment of multiple acyl-CoA-dehydrogenase deficiency (MADD) includes a low-fat, low-protein, high-carbohydrate diet, avoiding long fasting periods. However, there is no useful biochemical marker to determine the response to different diets or fasting periods. The aims of this study are to report a patient with ...

journal_title：Pediatric research

authors： Abdenur JE,Chamoles NA,Schenone AB,Jorge L,Guinle A,Bernard C,Levandovskiy V,Fusta M,Lavorgna S

更新日期：2001-07-01 00:00:00

abstract：:The purpose of this investigation was to determine whether maximal oxygen consumption (VO2max) differed between clinically obese black and white children and if a difference existed to determine whether it was related to hematological profiles and/or physical activity/inactivity levels. Twenty-three black and 21 white...

journal_title：Pediatric research

authors： Andreacci JL,Robertson RJ,Dubé JJ,Aaron DJ,Dixon CB,Arslanian SA

更新日期：2005-09-01 00:00:00

abstract：:Periventricular leukomalacia (PVL), the major substrate of neurologic deficits in premature infants, is associated with reduced white matter volume. Using immunomarkers of axonal pathology [beta-amyloid precursor protein (beta-APP) and apoptotic marker fractin], we tested the hypothesis that widespread (diffuse) axona...

journal_title：Pediatric research

authors： Haynes RL,Billiards SS,Borenstein NS,Volpe JJ,Kinney HC

更新日期：2008-06-01 00:00:00