Silane-based self-assembled monolayer deposited on fluorine doped tin oxide as model system for pharmaceutical and biomedical analysis.

Abstract:

:Recently, self-assembled monolayers (SAMs) are gaining a lot of interest due to their simplicity of preparation and wide applicability in the development of model systems used in pharmaceutical and biomedical analysis. The most efficient methods used for the investigation of SAM-based structures usually include cyclic voltammetry and electrochemical impedance spectroscopy. Scanning electrochemical microscopy (SECM) could be also used as an alternative method for SAM investigations, because this method enables to map modified surface. In this work, the surface of fluorine doped tin oxide (FTO) was modified with octadeciltrichlorosilane (OTS) based SAM and investigated using SECM. Measurements, which were carried out by SECM, lead to conclusion that highly heterogeneous and distributed monolayer has been formed on FTO surface.

journal_name

J Pharm Biomed Anal

authors

Gabriunaite I,Valiūnienė A,Poderyte M,Ramanavicius A

doi

10.1016/j.jpba.2019.112832

subject

Has Abstract

pub_date

2020-01-05 00:00:00

pages

112832

eissn

0731-7085

issn

1873-264X

pii

S0731-7085(19)31078-7

journal_volume

177

pub_type

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