Abstract:
PURPOSE:Some patients with respiratory failure fail initial weaning attempts and need prolonged mechanical ventilation (MV). Prolonged MV is associated with many complications and consumption of heathcare resources. Objective weaning indices help staffs to identify high-potential patients for weaning from the MV. Traditional weaning indices are not reliable in clinical practice. Transitional percentage of minute volume (TMV%) is a new index of the work of breathing. This study aimed to investigate the utility of TMV% in the prediction of weaning potential. METHODS:This study was prospectively performed including all patients with prolonged MV. Researchers recorded their demographics, TMV%, respiratory parameters, Acute Physiology and Chronic Health Evaluation II score, and laboratory data upon arrival at the respiratory care center. The factors associated with successful weaning were analyzed. RESULTS:Out of the 120 patients included, 84 (70.0%) were successfully weaned from MV. Traditional weaning indices such as rapid shallow breathing index could not predict the weaning outcome. TMV% was a valuable parameter as patients with a lower TMV%, higher tidal volume, higher hemoglobin, lower blood urea nitrogen, and lower Acute Physiology and Chronic Health Evaluation II scores had a higher rate of successful weaning. TMV%, tidal volume, and HCO3- levels were independent predictors of successful weaning, and the area under the curve was .79 in the logistic regression model. CONCLUSION:TMV% is a novel and effective predictor of successful weaning. Patients with lower TMV% had a higher MV weaning outcome. Once patients with a high potential for successful weaning are identified, they should be aggressively weaned from MV as soon as possible. CLINICAL TRIALS GOVERNMENT IDENTIFIER:NCT033480.
journal_name
Asian Nurs Res (Korean Soc Nurs Sci)journal_title
Asian nursing researchauthors
Liang YR,Yang MC,Wu YK,Tzeng IS,Wu PY,Huang SY,Lan CC,Wu CPdoi
10.1016/j.anr.2020.01.002subject
Has Abstractpub_date
2020-02-01 00:00:00pages
30-35issue
1eissn
1976-1317issn
2093-7482pii
S1976-1317(20)30002-5journal_volume
14pub_type
杂志文章abstract:PURPOSE:Metabolic syndrome is an important cluster of coronary heart disease risk factors. However, it remains unclear to what extent metabolic syndrome is associated with demographic and potentially modifiable lifestyle factors among Korean persons with physical disabilities. This study aimed to determine the prevalen...
journal_title:Asian nursing research
pub_type: 杂志文章
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journal_title:Asian nursing research
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journal_title:Asian nursing research
pub_type: 杂志文章,多中心研究
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journal_title:Asian nursing research
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journal_title:Asian nursing research
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journal_title:Asian nursing research
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journal_title:Asian nursing research
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:Asian nursing research
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journal_title:Asian nursing research
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journal_title:Asian nursing research
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journal_title:Asian nursing research
pub_type: 杂志文章,多中心研究
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更新日期:2014-06-01 00:00:00
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journal_title:Asian nursing research
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-03-01 00:00:00
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journal_title:Asian nursing research
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更新日期:2015-09-01 00:00:00
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