Assortative mating by population of origin in a mechanistic model of admixture.


:Populations whose mating pairs have levels of similarity in phenotypes or genotypes that differ systematically from the level expected under random mating are described as experiencing assortative mating. Excess similarity in mating pairs is termed positive assortative mating, and excess dissimilarity is negative assortative mating. In humans, empirical studies suggest that mating pairs from various admixed populations - whose ancestry derives from two or more source populations - possess correlated ancestry components that indicate the occurrence of positive assortative mating on the basis of ancestry. Generalizing a two-sex mechanistic admixture model, we devise a model of one form of ancestry-assortative mating that occurs through preferential mating based on source population. Under the model, we study the moments of the admixture fraction distribution for different assumptions about mating preferences, including both positive and negative assortative mating by population. We demonstrate that whereas the mean admixture under assortative mating is equivalent to that of a corresponding randomly mating population, the variance of admixture depends on the level and direction of assortative mating. We consider two special cases of assortative mating by population: first, a single admixture event, and second, constant contributions to the admixed population over time. In contrast to standard settings in which positive assortment increases variation within a population, certain assortative mating scenarios allow the variance of admixture to decrease relative to a corresponding randomly mating population: with the three populations we consider, the variance-increasing effect of positive assortative mating within a population might be overwhelmed by a variance-decreasing effect emerging from mating preferences involving other pairs of populations. The effect of assortative mating is smaller on the X chromosome than on the autosomes because inheritance of the X in males depends only on the mother's ancestry, not on the mating pair. Because the variance of admixture is informative about the timing of admixture and possibly about sex-biased admixture contributions, the effects of assortative mating are important to consider in inferring features of population history from distributions of admixture values. Our model provides a framework to quantitatively study assortative mating under flexible scenarios of admixture over time.


Theor Popul Biol


Goldberg A,Rastogi A,Rosenberg NA




Has Abstract


2020-08-01 00:00:00












  • The number of lines of descent and fixation probabilities of alleles in the pure genetic drift process: analytical approximations.

    abstract::Analysis of diversity between populations diverged from an evolutionarily small number of generations cannot be done under the assumption that allele frequencies reflect an equilibrium between genetic drift and mutations. An alternative to analysis through coalescence theory is proposed in this situation by developing...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Chevalet C

    更新日期:2000-03-01 00:00:00

  • Extinction probabilities and stationary distributions of mobile genetic elements in prokaryotes: The birth-death-diversification model.

    abstract::Theoretical approaches are essential to our understanding of the complex dynamics of mobile genetic elements (MGEs) within genomes. Recently, the birth-death-diversification model was developed to describe the dynamics of mobile promoters (MPs), a particular class of MGEs in prokaryotes. A unique feature of this model...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Drakos NE,Wahl LM

    更新日期:2015-12-01 00:00:00

  • Local facilitation, bistability and transitions in arid ecosystems.

    abstract::Arid ecosystems are liable to undergo sudden discontinuous transitions from a vegetated to a desert state as a result of human pressure and climate change. A predictive framework about the conditions under which such transitions occur is lacking. Here, we derive and analyze a general model describing the spatial dynam...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Kéfi S,Rietkerk M,van Baalen M,Loreau M

    更新日期:2007-05-01 00:00:00

  • Sexual selection by male choice in monogamous and polygynous human populations.

    abstract::The theoretical possibility of coevolution of a viability-reducing female physical trait and a male mating preference for that trait by Fisherian sexual selection in monogamous and polygynous populations is demonstrated using two-locus haploid models. It is assumed that there is dichotomous variation in male resources...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Ihara Y,Aoki K

    更新日期:1999-02-01 00:00:00

  • Inferring the demographic history from DNA sequences: An importance sampling approach based on non-homogeneous processes.

    abstract::In Ait Kaci Azzou et al. (2015) we introduced an Importance Sampling (IS) approach for estimating the demographic history of a sample of DNA sequences, the skywis plot. More precisely, we proposed a new nonparametric estimate of a population size that changes over time. We showed on simulated data that the skywis plot...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Ait Kaci Azzou S,Larribe F,Froda S

    更新日期:2016-10-01 00:00:00

  • Population-genetic models of sex-limited genomic imprinting.

    abstract::Genomic imprinting is a form of epigenetic modification involving parent-of-origin-dependent gene expression, usually the inactivation of one gene copy in some tissues, at least, for some part of the diploid life cycle. Occurring at a number of loci in mammals and flowering plants, this mode of non-Mendelian expressio...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Kelly ST,Spencer HG

    更新日期:2017-06-01 00:00:00

  • Fixation in haploid populations exhibiting density dependence I: The non-neutral case.

    abstract::We extend the one-locus two allele Moran model of fixation in a haploid population to the case where the total size of the population is not fixed. The model is defined as a two-dimensional birth-and-death process for allele number. Changes in allele number occur through density-independent death events and birth even...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Parsons TL,Quince C

    更新日期:2007-08-01 00:00:00

  • Evolution of disassortative and assortative mating preferences based on imprinting.

    abstract::A two-locus haploid model of sexual selection is investigated to explore evolution of disassortative and assortative mating preferences based on imprinting. In this model, individuals imprint on a genetically transmitted trait during early ontogeny and choosy females later use those parental images as a criterion of m...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Ihara Y,Feldman MW

    更新日期:2003-09-01 00:00:00

  • Theoretical recombination processes incorporating interference effects.

    abstract::With the acquisition of genetic, physical, and sequence maps, linkage relationships among genes (markers) may be more accurately approached in terms of global models for the distribution of recombination events that take into account interference. There are two principal analytical methods used for ascertaining linkag...

    journal_title:Theoretical population biology

    pub_type: 杂志文章,评审


    authors: Karlin S,Liberman U

    更新日期:1994-10-01 00:00:00

  • Maximum likelihood estimators for scaled mutation rates in an equilibrium mutation-drift model.

    abstract::The stationary sampling distribution of a neutral decoupled Moran or Wright-Fisher diffusion with neutral mutations is known to first order for a general rate matrix with small but otherwise unconstrained mutation rates. Using this distribution as a starting point we derive results for maximum likelihood estimates of ...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Vogl C,Mikula LC,Burden CJ

    更新日期:2020-08-01 00:00:00

  • Spatially structured metapopulation models: global and local assessment of metapopulation capacity.

    abstract::We model metapopulation dynamics in finite networks of discrete habitat patches with given areas and spatial locations. We define and analyze two simple and ecologically intuitive measures of the capacity of the habitat patch network to support a viable metapopulation. Metapopulation persistence capacity lambda(M) def...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Ovaskainen O,Hanski I

    更新日期:2001-12-01 00:00:00

  • Microbial dormancy and boom-and-bust population dynamics under starvation stress.

    abstract::We propose a model for the growth of microbial populations in the presence of a rate-limiting nutrient which accounts for the switching of cells to a dormant phase at low densities in response to decreasing concentration of a putative biochemical signal. We then show that in conditions of nutrient starvation, self-sus...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Fowler AC,Winstanley HF

    更新日期:2018-03-01 00:00:00

  • Match probabilities in a finite, subdivided population.

    abstract::We generalize a recently introduced graphical framework to compute the probability that haplotypes or genotypes of two individuals drawn from a finite, subdivided population match. As in the previous work, we assume an infinite-alleles model. We focus on the case of a population divided into two subpopulations, but th...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Malaspinas AS,Slatkin M,Song YS

    更新日期:2011-05-01 00:00:00

  • Additive genetic variation under intraspecific competition and stabilizing selection: a two-locus study.

    abstract::A diallelic two-locus model is investigated in which the loci determine the genotypic value of a quantitative trait additively. Fitness has two components: stabilizing selection on the trait and a frequency-dependent component, as induced, for instance, if the ability to utilize different food resources depends on thi...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Bürger R

    更新日期:2002-03-01 00:00:00

  • Consequences of an uncertain mass mortality regime triggered by climate variability on giant clam population management in the Pacific Ocean.

    abstract::Despite actions to manage sustainably tropical Pacific Ocean reef fisheries, managers have faced failures and frustrations because of unpredicted mass mortality events triggered by climate variability. The consequences of these events on the long-term population dynamics of living resources need to be better understoo...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Van Wynsberge S,Andréfouët S,Gaertner-Mazouni N,Remoissenet G

    更新日期:2018-02-01 00:00:00

  • Discrete clutch sizes, local mate competition, and the evolution of precise sex allocation.

    abstract::Optimal sex allocation under a population structure with local mate competition has been studied mainly in deterministic models that are based on the assumption of continuous clutch sizes; Hamilton's (1967) model is the classic example. When clutch sizes are small, however, this assumption is not appropriate. When tak...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Nagelkerke CJ

    更新日期:1996-06-01 00:00:00

  • Optimal Level of Chemical Defense Decreasing with Leaf Age

    abstract::A recent study on a biennial plant demonstrated that pyrrolizidine alkaloids decrease with the age of leaves due to reallocation from old leaves to new leaves. Here we study the optimal age-specific pattern of defense chemical concentration in leaves that achieves the maximum growth rate of the plant. We consider a pl...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Iwasa Y,Kubo T,van Dam N,de Jong TJ

    更新日期:1996-10-01 00:00:00

  • Canards and mixed-mode oscillations in a forest pest model.

    abstract::We consider a three-variable forest pest model, proposed by Rinaldi & Muratori (1992) [Rinaldi, S., Muratori, S., 1992. Limit cycles in slow-fast forest-pest models. Theor. Popul. Biol. 41, 26-43]. The model allows relaxation oscillations where long pest-free periods are interspersed with outbreaks of high pest concen...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Brøns M,Kaasen R

    更新日期:2010-06-01 00:00:00

  • On ordered subpopulations and population mortality at advanced ages.

    abstract::We consider hazard (mortality) rates in heterogeneous populations consisting of ordered (in the defined stochastic sense) subpopulations. This setting can be interpreted via the fixed frailty models with one or more frailty parameters. The shape of the hazard rate is of main interest in this paper. Specifically, the d...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Finkelstein M

    更新日期:2012-06-01 00:00:00

  • A temporal model of territorial defence with antagonistic interactions.

    abstract::Territorial behaviour is an important part of the lives of many animals. Once a territory has been acquired, an animal may spend its entire life on it, and may have to repeatedly defend it from conspecifics. Some species make great investments in the defence of a territory, and this defence can be costly, in terms of ...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Varga T,Garay J,Rychtář J,Broom M

    更新日期:2020-08-01 00:00:00

  • Harsh environments and the evolution of multi-player cooperation.

    abstract::The game-theoretic model in this paper provides micro-foundations for the effect a harsher environment on the probability of cooperation among multiple players. The harshness of the environment is alternatively measured by the degree of complementarity between the players' cooperative efforts in producing a public goo...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: De Jaegher K

    更新日期:2017-02-01 00:00:00

  • Statistical properties of segregating sites.

    abstract::A mutation leading to a segregating site of a sample can be classified by the number of sequences in the sample that inherits the mutant nucleotide; it can also be classified by the frequencies of the two segregating nucleotides at the resulting segregating side. We define the size of a mutation to be the number of se...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Fu YX

    更新日期:1995-10-01 00:00:00

  • Competition landscapes: scaling up local biotic and abiotic processes in heterogeneous environments.

    abstract::I present a model based on benthic populations by first defining a competition landscape where competitive interactions are confined to small areas, defined by the distribution of resource renewal from a global pool. Using truncated kernels and results from 1-dimensional percolation theory, I then derive an approximat...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Guichard FF

    更新日期:2004-09-01 00:00:00

  • The shape of things to come: using models with physiological structure to predict mortality trajectories.

    abstract::If mortality rate is viewed as the outcome of processes of behavior, growth and reproduction, then it should be possible to predict mortality rate as a result of those processes. We provide two examples of how this may be done. In the first, we use the method of linear chains to treat mortality that is the result of m...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Mangel MM,Bonsall MB

    更新日期:2004-06-01 00:00:00

  • Competition and stoichiometry: coexistence of two predators on one prey.

    abstract::The competitive exclusion principle (CEP) states that no equilibrium is possible if n species exploit fewer than n resources. This principle does not appear to hold in nature, where high biodiversity is commonly observed, even in seemingly homogenous habitats. Although various mechanisms, such as spatial heterogeneity...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Loladze I,Kuang Y,Elser JJ,Fagan WF

    更新日期:2004-02-01 00:00:00

  • Population dynamics and competitive outcome derive from resource allocation statistics: The governing influence of the distinguishability of individuals.

    abstract::Model predictions for species competition outcomes highly depend on the assumed form of the population growth function. In this paper we apply an alternative inferential method based on statistical mechanics, maximizing Boltzmann entropy, to predict resource-constrained population dynamics and coexistence. Within this...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Zhang YJ,Harte J

    更新日期:2015-11-01 00:00:00

  • Modeling biological invasions into periodically fragmented environments.

    abstract::Range expansion of a single species in a regularly striped environment is studied by using an extended Fisher model, in which the rates of diffusion and reproduction periodically fluctuate between favorable and unfavorable habitats. The model is analyzed for two initial conditions: the initial population density is co...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Kinezaki N,Kawasaki K,Takasu F,Shigesada N

    更新日期:2003-11-01 00:00:00

  • Fixed point sensitivity analysis of interacting structured populations.

    abstract::Sensitivity analysis of structured populations is a useful tool in population ecology. Historically, methodological development of sensitivity analysis has focused on the sensitivity of eigenvalues in linear matrix models, and on single populations. More recently there have been extensions to the sensitivity of nonlin...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Barabás G,Meszéna G,Ostling A

    更新日期:2014-03-01 00:00:00

  • Properties of the major gene index for three-allele and two-locus models.

    abstract::The expected value of the MGI(2) statistic was evaluated for several three-allele and two-locus models for which we have specified dominance relationships among phenotype classes based on heterozygote and homozygote genotype groupings. In a parallel simulation study we investigated the nature of MGI(alpha) for alpha =...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Carmelli D,Cameron E

    更新日期:1983-04-01 00:00:00

  • Gene-culture coevolution under selection.

    abstract::The joint evolutionary dynamics of phenotypes and genotypes are usually couched in terms of genetic variance contributions to changes in the phenotypic mean. Here, we study the evolution of a dichotomous phenotype whose transmission is controlled by one multi-allelic locus. The phenotype is under selection, which may ...

    journal_title:Theoretical population biology

    pub_type: 杂志文章


    authors: Behar H,Feldman MW

    更新日期:2018-05-01 00:00:00