Molecular underpinnings of systemic treatment resistance in metastatic castration-resistant prostate cancer

abstract：:Nijmegen Breakage syndrome is a rare, autosomal recessive disorder characterized by severe, combined immunodeficiency, recurrent sinopulmonary infections, chromosomal instability, radiosensitivity, predisposition to malignancy, a "bird-like" facial appearance, progressive microcephaly, short stature, and mental retard...

journal_title：Orvosi hetilap

authors： Erdos M,Tóth B,Juhász P,Mahdi M,Maródi L

更新日期：2010-04-18 00:00:00

abstract：:The Curling's ulcer is a special form of the stress ulcers which occurs in the stomach and duodenum in 2.0-25%. It's pathogenesis is unknown even though it is clearly related to larger burns poor early treatment and septic complications. Since the institution of routine prophylaxis of H2 receptor antagonists and antac...

journal_title：Orvosi hetilap

authors： Baksa J

更新日期：1991-02-24 00:00:00

abstract：:Similarly to an increase in life expectancy, the incidence of Parkinson's disease increases as well. In parallel with this, more patients with Parkinson's disease undergo elective or urgent surgical interventions. According to recent statistical data, more than half of the patients with Parkinson's disease are not pro...

journal_title：Orvosi hetilap

authors： Fülesdi B,Mitre C,Molnár C

更新日期：2015-08-23 00:00:00

abstract：:The receptor scintigraphy of the dopaminergic system of the brain is of interest in the evaluation of movement disorders. The 123I-IBZM is a radiopharmaceutical with affinity predominantly to postsynaptic D2 receptors. The aim of this study was to evaluate the role of IBZM SPECT investigations in the differentiation o...

journal_title：Orvosi hetilap

authors： Pávics L,Dibó G,Ambrus E,Séra T,Vécsei L,Csernay L

更新日期：2000-05-14 00:00:00

abstract：:The endothelium is a major regulator of vascular tone, releasing vasoconstrictive (endothelin, cyclooxigenase-dependent factors, including prostanoids and oxygen free radicals) and vasodilating (endothelium--derived nitric oxid, endothelium--derived hyperpolarizing factor) mediators. These biologically active substanc...

journal_title：Orvosi hetilap

authors： Nagy J,Csiky B,Kovács T,Wittmann I

更新日期：2001-08-05 00:00:00

abstract：:A 23-year-old woman presented with a thyroid mass and total thyroidectomy was performed. Histological examination revealed papillary thyroid carcinoma. In the postoperative period severe hypocalcaemia due to permanent hypoparathyroidism developed. After postoperative telecobalt irradiation and substitutional hormone t...

journal_title：Orvosi hetilap

authors： Kovács EM,Rigó J Jr,Tóth M

更新日期：2003-07-27 00:00:00

abstract：INTRODUCTION:The high prevalence of morbidity among female physicians in Hungary is well documented, however, little is known about the prevalence of that in certain age groups. AIMS:To assess the prevalence of somatic and psychiatric morbidity in two age cohorts (Cohort 1: age 24-43 and Cohort 2: age 44-76) of female...

journal_title：Orvosi hetilap

authors： Győrffy Z,Adám S

更新日期：2013-01-06 00:00:00

abstract：:Complications of chronic liver diseases requiring surgical interventions are the following: esophageal varices and bleeding, ascites hypersplenism, some forms of liver insufficiency. The most widely accepted method for treatment of esophageal varices is endoscopic sclerotherapy. Portal systemic shunts are indicated in...

journal_title：Orvosi hetilap

authors： Kupcsulik P

更新日期：1992-08-09 00:00:00

abstract：:A case report of a rare, presumably congenital form of "single coronary artery", is presented. The authors review the classification and clinical significance of the entity with special emphasis with regard to anginal symptoms and the so called sudden unexpected death syndrome. Details and result of surgical intervent...

journal_title：Orvosi hetilap

authors： Vaszily M,Zöllei E,Rudas L,Boda L,Ungi I,Gaál T,Török Z

更新日期：1995-10-22 00:00:00

abstract：:Seven children with albinism were examined for haemorrhagic diathesis. In 6 patients coagulation screening tests (prothrombin time, activated partial thromboplastin time, thrombin time) were normal, in 1 patient prolongation of activated partial thromboplastin time due to mild factor XI deficiency was found. Platelet ...

journal_title：Orvosi hetilap

authors： Pap Z,Ajzner E,Kiss C,Emódy J,Závodszky I,Horváth A,Muszbek L

更新日期：1997-02-23 00:00:00

abstract：:The authors present their experience with the endoscopic kidney stone removal in pediatric patients. They treated 55 children under 14 with this method. If the stone was large they used ultrasonic disintegration. On the basis of their own experience and the technical literature they assert that most of the pediatric k...

journal_title：Orvosi hetilap

authors： Holman E,Tóth C

更新日期：1989-08-27 00:00:00

abstract：:Having screened 384 patients suffering from Scheuermann's disease and 2992 eleven-year-old children, the authors conclude that the early and salient symptoms of the disease are mobile thoracic kyphosis associated with the flexious contracture of the hip joint, and occasional anteflexious contracture of the shoulder jo...

journal_title：Orvosi hetilap

authors： Viola S,Rimaszombati K

更新日期：1990-12-09 00:00:00

abstract：UNLABELLED:The associations of the ABO- and Rh-blood groups, the serum cholesterol and the extent of the coronary artery disease were examined in 653 patients who underwent coronary angiography between 1980 and 1985 in the Hungarian Institute of Cardiology. CONCLUSIONS:1. among the patients with positive coronarograph...

journal_title：Orvosi hetilap

authors： Tarján Z,Tonelli M,Duba J,Zorándi A

更新日期：1995-04-09 00:00:00

abstract：:This article reviews the recent changes in the understanding of acute pancreatitis pathophysiology emphasizing results deriving from the more detailed comprehension of the local and systemic aspects of the inflammatory process. The authors briefly discuss those theories that have been influencing the basic philosophie...

journal_title：Orvosi hetilap

authors： Telek G,Fehér J,Jakab F,Claude R

更新日期：2000-02-06 00:00:00

abstract：CASE REPORT:A 47 year old female with severe deficiency of three limbs visited our Genetic Counselling Clinic and asked us to give her a certificate that her complex limb deficiency was caused by thalidomide (Contergan). According to her explanation, her mother used this drug during pregnancy which was given to her by ...

journal_title：Orvosi hetilap

authors： Gidai J,Bács E,Czeizel E

更新日期：2009-06-21 00:00:00

abstract：:Congenital adrenal hyperplasia is a group of genetic diseases due to the disablement of 7 genes; one of them is steroid 21-hydroxylase deficiency. The genes of congenital adrenal hyperplasia encode enzymes taking part in the steroidogenesis of adrenal gland. Steroid 21-hydroxylase deficiency is an autosomal recessive ...

journal_title：Orvosi hetilap

authors： Doleschall M,Török D,Mészáros K,Luczay A,Halász Z,Németh K,Szücs N,Kiss R,Tőke J,Sólyom J,Fekete G,Patócs A,Igaz P,Tóth M

更新日期：2018-02-01 00:00:00

abstract：:Ghrelin: a new peptide regulating the neurohormonal system and energy homeostasis. Research leading to the identification of ghrelin started with the discovery of growth hormone secretagogues, continued with the description of ghrelin receptors and ended with description of the chemical structure of ghrelin. However, ...

journal_title：Orvosi hetilap

authors： Pusztai P,Somogyi A,Rácz K,Tulassay Z

更新日期：2004-12-19 00:00:00

abstract：UNLABELLED:The need of outcome measures from the patients' aspect emerges reasonably in the field of rapidly developing pediatric cardiac surgery and pediatric cardiology. The professional standards and the possibilities of applicability of quality of life measures are often unknown for medical doctors. This is particu...

journal_title：Orvosi hetilap

authors： Berkes A,Mogyorósy G

更新日期：2008-09-14 00:00:00

abstract：INTRODUCTION:Examination of the gut-liver axis came into the spotlight worldwide. Liver enzyme elevations are commonly seen in patients with inflammatory bowel disease (IBD), which is a diagnostic challenge in everyday clinical practice. Liver and biliary diseases are common extra-intestinal manifestations in Crohn's d...

journal_title：Orvosi hetilap

authors： Egresi A,Kovács Á,Szilvás Á,Blázovics A

更新日期：2017-07-01 00:00:00

abstract：:Introduction: It is known that lactate concentration is increased in diabetic ketoacidosis (DKA), however, the pathophysiology and kinetics of lactate changes are still unclear. Normally, L-lactate is the major form in the human body. According to previous data, also D- and L-lactate might be increased in hyperglycaem...

journal_title：Orvosi hetilap

authors： Jenei K,Szatmári I,Szabó E,Mariam A,Luczay A,Zsidegh P,Tóth-Heyn P

更新日期：2019-11-01 00:00:00

abstract：UNLABELLED:Transplant patients' attitudes and representations related to their illness, their body, and the healing process have a significant impact on their recovery. AIMS:The study involved 51 patients from the Department of Surgery, University of Szeged, Hungary. The primary aim was to examine the possible connect...

journal_title：Orvosi hetilap

authors： Látos M,Barabás K,Lázár G,Marofka F,Szederkényi E,Szenohradszky P,Csabai M

更新日期：2012-04-15 00:00:00

abstract：:The incidence of the premature LH-rise/peak has been analysed in view to the pregnancy rate in 139 HMG and combined Buserelin + HMG cycles of an IVF-ET/GIFT program. A premature LH-rise/peak seems to be correlated with a lower pregnancy rate; therefore the cancellation of the stimulation is recommended in these cases....

journal_title：Orvosi hetilap

authors： Urbancsek J,Csömör S,Benno R,Thomas R,Sztanyik L,Klaus G

更新日期：1990-04-29 00:00:00

abstract：:The author accounts about twenty patients operated on tubal pregnancy established on ultrasonic and laparoscopy. He refers the history of the methods of surgical interventions and the difficulties of the diagnosis nowadays. He makes known the technics of the laparoscopical operation and the operated patients' postoper...

journal_title：Orvosi hetilap

authors： Tóth Ferenc Z

更新日期：1993-01-24 00:00:00

abstract：:Changes of left ventricular systolic function in acute myocardial infarction are well known. However, diastolic function may also have a role for patients' symptoms and prognosis. The purpose of this study was to evaluate changes of diastolic function non-invazively and to delineate the relation between systolic and d...

journal_title：Orvosi hetilap

authors： Temesvári A,Kaare S

更新日期：1996-02-25 00:00:00

abstract：UNLABELLED:The effect of supplementary Vitamin E on the vitamin content of lipoproteins in young men and women. Inappropriate vitamin and trace element supplementation may facilitate the development of atherosclerosis. It is known that Vitamin E protects lipids from oxidative stress, while clinical signs of atheroscler...

journal_title：Orvosi hetilap

authors： Somogyi A,Herold M,Kocsis I,Nagy G,Somfai G,Studinger P

更新日期：2005-08-28 00:00:00

abstract：:Circulating markers of neuroendocrine tumours are useful tools in the diagnosis of these tumours. Laboratory tests for general biomarkers have acceptable sensitivity for the recognition of neuroendocrine tumours as these biologically active proteins are typically synthesized by all types of neuroendocrine cells. Measu...

journal_title：Orvosi hetilap

authors： Tőke J,Czirják G,Tóth M,Rácz K,Patócs A

更新日期：2014-11-09 00:00:00

abstract：:When taken during pregnancy, the earlier types of contraceptive pills had a direct teratogenic effect on the female fetus, causing the masculinization syndrome. Presently available pills, which are of different composition and given in smaller doses, do not have a direct teratogenic effect when taken during pregnancy...

journal_title：Orvosi hetilap

authors： Czeizel E

更新日期：1980-01-06 00:00:00

abstract：:(Drug-eluting stents substantially reduce the incidence of restenosis after percutaneous coronary interventions.) The cytostatic drugs however not only inhibit the proliferation of smooth muscle cell and neointima proliferation but also delay the endothelisation of the stent struts. It may result in persistent inflamm...

journal_title：Orvosi hetilap

authors： Keltai M

更新日期：2007-03-11 00:00:00

abstract：:Data of the morbidity and mortality index of the acute coronary heart disease in the South Trans-Danubian Region between 1999 and 2002. South Trans-Danubian Regional Acute Coronary Registry. Based on GYOGYINFOK database, the authors' purpose was to monitor the morbidity and mortality of acute coronary heart diseases (...

journal_title：Orvosi hetilap

authors： Németh C,Tüzes K,Józan-Jilling M,Papp L

更新日期：2004-10-17 00:00:00

abstract：:Rehabilitation of the patients following open heart surgery is strongly influenced by the psychological conditions. Depression plays a crucial negative role in this process. Depression score was measured in patients taking part in the rehabilitation course of our institute last year (1998), 6 weeks after discharge fro...

journal_title：Orvosi hetilap

authors： Székely A,Benkö E,Varga A,Mészáros R

更新日期：2001-10-14 00:00:00