Schisandrosides A-D, Dibenzocyclooctadiene Lignan Glucosides from the Roots of Schisandra chinensis.


:Four new dibenzocyclooctadiene lignan glucosides, schisandrosides A-D (1-4), as well as two known rare nortriterpenoids, micrandilactone C (5) and propindilactone Q (6), were isolated from the roots of Schisandra chinensis BAILLON (Schisandraceae). The structure of compounds 1-4 were elucidated by physical and spectroscopic data interpretation. To the best of our knowledge, schisandrosides A-D (1-4) represent the first example of a dibenzocyclooctadiene lignan glycoside.


Kim HM,Ryu B,Lee JS,Choi JH,Jang DS




Has Abstract


2015-01-01 00:00:00












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    abstract::A new cardenolide diglycoside (1) was isolated from Nerium oleander together with ten known cardenolide diglycosides 2-11. The structure of compound 1 was established on the basis of their spectroscopic data. The in vitro anti-inflammatory activity of compounds 1-11 was examined on the basis of inhibitory activity aga...

    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Zhao M,Bai L,Toki A,Hasegawa R,Sakai J,Hasegawa T,Ogura H,Kataoka T,Bai Y,Ando M,Hirose K,Ando M

    更新日期:2011-01-01 00:00:00

  • Synthesis and in Vitro Antibacterial Evaluation of Novel 4-Substituted 1-Menthyl-1,2,3-triazoles.

    abstract::Menthyl 1,4-disubstituted 1,2,3-triazole derivatives of hydroxybenzaldehydes, phenols and bile acids were synthesized via click chemistry. The novel synthesized compounds were evaluated for their in vitro antibacterial activity against Enterococcus faecium, and Staphylococcus aureus as Gram-positive bacteria. Some der...

    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Khaligh P,Salehi P,Bararjanian M,Aliahmadi A,Khavasi HR,Nejad-Ebrahimi S

    更新日期:2016-01-01 00:00:00

  • Preparation of Amorphous Composite Particles of Drugs with Ursodeoxycholic Acid as Preclinical Formulations.

    abstract::We studied the possibility of using ursodeoxycholic acid (UDCA) as an excipient to create an amorphous composite that can be administered to animals in preclinical studies of experimental drugs. Three UDCA-based amorphous samples composed of nifedipine (NIF), indomethacin (IND), and naproxen (NAP) were found by screen...

    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Tanida S,Yoshimoto A,Yoshida M,Uchiyama H,Kadota K,Tozuka Y

    更新日期:2019-01-01 00:00:00

  • Hydrophobicity parameters determined by reversed-phase liquid chromatography. XVI: A new hydrogen-accepting parameter for monosubstituted thiophenes and furans for correlating retention factors and octanol-water partition coefficients.

    abstract::We recently proposed a new hydrogen-accepting parameter, S(HA), for monosubstituted (di)azines on the basis of the heat of formation calculated by the conductor-like screening model (COSMO) method. In this work, S(HA) values for monosubstituted thiophenes and furans were calculated and the results were applied to the ...

    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Yamagami C,Tachikawa H

    更新日期:2003-10-01 00:00:00

  • Synthesis and pharmacological evaluation of new progesterone esters as 5alpha-reductase inhibitors.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Ramírez E,Cabeza M,Bratoeff E,Heuze I,Pérez V,Valdez D,Ochoa M,Teran N,Jimenez G,Ramírez T

    更新日期:2005-12-01 00:00:00

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    abstract::A new toxic neoanisatin-derivative (1) was isolated from the pericarps of Illicium majus. The structure of this compound was elucidated by spectroscopic data, including the 2D COSY NMR technique. The toxicity of compound 1 is also described. ...

    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Yang CS,Hashimoto M,Baba N,Takahashi M,Kaneto H,Kawano N,Kouno I

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    abstract::High-performance liquid chromatography coupled with solid phase extraction method was developed for determination of isofraxidin in rat plasma after oral administration of Acanthopanax senticosus extract (ASE), and pharmacokinetic parameters of isofraxidin either in ASE or pure compound were measured. The HPLC analysi...

    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Sun H,Lv H,Zhang Y,Wang X,Bi K,Cao H

    更新日期:2007-09-01 00:00:00

  • On the interaction of doxorubicin with oleate ions: fluorescence spectroscopy and liquid-liquid extraction study.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Munnier E,Tewes F,Cohen-Jonathan S,Linassier C,Douziech-Eyrolles L,Marchais H,Soucé M,Hervé K,Dubois P,Chourpa I

    更新日期:2007-07-01 00:00:00

  • Finding of primitive polyamine toxins in the venom of a joro spider, Nephila clavata.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Chiba T,Akizawa T,Matsukawa M,Pan-Hou H,Yoshioka M

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  • Oxygenated hexylitaconates from a marine sponge-derived fungus Penicillium sp.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Li JL,Zhang P,Lee YM,Hong J,Yoo ES,Bae KS,Jung JH

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Sato K,Inaba Y,Park HS,Akiyama T,Koyama T,Fukaya H,Aoyagi Y,Takeya K

    更新日期:2009-07-01 00:00:00

  • 2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ Activation.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Morishita K,Shoji Y,Fukui M,Ito Y,Kitao T,Ozawa SI,Hirono S,Shirahase H

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  • Purification and properties of multiple forms of dihydrodiol dehydrogenase from monkey liver.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Nakagawa M,Harada T,Hara A,Nakayama T,Sawada H

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  • Synthesis of 2-O-(4-coumaroyl)-3-(4-hydroxyphenyl)lactic acid, an important intermediate of rosmarinic acid biosynthesis.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Matsuno M,Nagatsu A,Ogihara Y,Mizukami H

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    abstract::The interaction of halofantrine with phosphatidylcholine and phosphatidylethanolamine bilayers has been investigated by differential scanning calorimetry. Halofantrine caused a broadening of the gel to liquid crystalline phase transition endotherm of the phosphatidylcholines. A decrease in the transition temperature T...

    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Lim LY,Go ML

    更新日期:1999-06-01 00:00:00

  • Benzoxazines. II. Synthesis, conformational analysis, and structure--activity relationships of 3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide derivatives as potent and long-acting serotonin-3 (5-HT3) receptor antagonists.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Kuroita T,Marubayashi N,Sano M,Kanzaki K,Inaba K,Kawakita T

    更新日期:1996-11-01 00:00:00

  • Electrochemical oxidation of anti-tumor agent, etoposide.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Sakurai K,Haga K,Ogiso T

    更新日期:1992-08-01 00:00:00

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Takahashi K,Tamagawa S,Katagi T,Yoshitomi H,Kamada A,Rytting JH,Nishihata T,Mizuno N

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  • Efficient improved extraction of tomato saponin using shock waves.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Manabe H,Takemoto A,Maehara H,Ohno M,Murakami Y,Itoh S,Nohara T

    更新日期:2011-01-01 00:00:00

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Yamaguchi M,Takehiro O,Ishida J,Nakamura M

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Miyake Y,Shigetoshi M,Kojima M

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  • Development and validation of liquid chromatographic and UV derivative spectrophotometric methods for the determination of famciclovir in pharmaceutical dosage forms.

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Andrés Pérez J,Boluda C,López H,Manuel Trujillo J

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Fukuyama Y,Hasegawa T,Toda M,Kodama M,Okazaki H

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Chen LC,Juang SH,Chang KM,Tzeng CC,Chen JJ,Chen IL,Wang TC

    更新日期:2014-01-01 00:00:00

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Mikolasch A,Hessel S,Salazar MG,Neumann H,Manda K,Gōrdes D,Schmidt E,Thurow K,Hammer E,Lindequist U,Beller M,Schauer F

    更新日期:2008-06-01 00:00:00

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Chen CR,Liao YW,Wang L,Kuo YH,Liu HJ,Shih WL,Cheng HL,Chang CI

    更新日期:2010-12-01 00:00:00

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Koutaka H,Kosuge J,Fukasaku N,Hirano T,Kikuchi K,Urano Y,Kojima H,Nagano T

    更新日期:2004-06-01 00:00:00

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    journal_title:Chemical & pharmaceutical bulletin

    pub_type: 杂志文章


    authors: Hori N,Tsukamoto G,Imamura A,Ohashi M,Saito T,Yoshino K

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