Abstract:
PURPOSE:The transinguinal preperitoneal approach is a relatively new technique for inguinal hernia repair. Two types of memory-ring mesh are available in Japan: the modified Kugel patch (MK) and the Polysoft patch (PP). We tested the hypothesis that the PP is noninferior to the MK with respect to chronic postoperative pain. METHODS:An unblinded randomized controlled trial was conducted to assess the noninferiority of PP compared to MK with a 5 % noninferiority margin. A total of 442 inguinal hernia patients operated on from November 2010 to December 2012 were included in this study. The primary endpoint was the pain score assessed by the visual analog scale (VAS) (0-1 vs. 2-10) 1 year after surgery. RESULTS:The patients were randomized to the PP and MK groups (n = 221 each). One year after surgery, 206 patients (95.4 %) in the PP group and 182 patients (89.6 %) in the MK group rated pain at 0-1 on the VAS scale. According to this rating, the PP group appeared not to be inferior to the MK group (95 % confidence interval, 0.7-10.7 %, P < 0.05). Furthermore, crude superiority tests, adjusting for 1 month of pain, denoted that the outcomes were significantly improved with the PP compared to the MK. CONCLUSIONS:The use of the PP was noninferior to the MK with respect to the severity of postoperative chronic pain scores 12 months after surgery.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Okinaga K,Hori T,Inaba T,Yamaoka Kdoi
10.1007/s00595-015-1228-xsubject
Has Abstractpub_date
2016-06-01 00:00:00pages
691-8issue
6eissn
0941-1291issn
1436-2813pii
10.1007/s00595-015-1228-xjournal_volume
46pub_type
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