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The value of S-Detect in improving the diagnostic performance of radiologists for the differential diagnosis of thyroid nodules.

Abstract：

AIMS:To compare the diagnostic value of S-Detect (a computer aided diagnosis system using deep learning) in differentiating thyroid nodules in radiologists with different experience and to assess if S-Detect can improve the diagnostic performance of radiologists. MATERIALS AND METHODS:Between February 2018 and October 2019, 204 thyroid nodules in 181 patients were included. An experienced radiologist performed ultrasound for thyroid nodules and obtained the result of S-Detect. Four radiologists with different experience on thyroid ultrasound (Radiologist 1, 2, 3, 4 with 1, 4, 9, 20 years, respectively) analyzed the conventional ultrasound images of each thyroid nodule and made a diagnosis of "benign" or "malignant" based on the TI-RADS category. After referring to S-Detect results, they re-evaluated the diagnoses. The diagnostic performance of radiologists was analyzed before and after referring to the results of S-Detect. RESULTS:The accuracy, sensitivity, specificity, positive predictive value and negative predictive value of S-Detect were 77.0, 91.3, 65.2, 68.3 and 90.1%, respectively. In comparison with the less experienced radiologists (radiologist 1 and 2), S-Detect had a higher area under receiver operating characteristic curve (AUC), accuracy and specificity (p <0.05). In comparison with the most experienced radiologist, the diagnostic accuracy and AUC were lower (p<0.05). In the less experienced radiologists, the diagnostic accuracy, specificity and AUC were significantly improved when combined with S-Detect (p<0.05), but not for experienced radiologists (radiologist 3 and 4) (p>0.05). CONCLUSIONS:S-Detect may become an additional diagnostic method for the diagnosis of thyroid nodules and improve the diagnostic performance of less experienced radiologists.

journal_name

Med Ultrason

journal_title

Medical ultrasonography

authors

Wei Q,Zeng SE,Wang LP,Yan YJ,Wang T,Xu JW,Zhang MY,Lv WZ,Cui XW,Dietrich CF

doi

10.11152/mu-2501

subject

Has Abstract

pub_date

2020-11-18 00:00:00

pages

415-423

issue

eissn

1844-4172

issn

2066-8643

journal_volume

pub_type

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The value of S-Detect in improving the diagnostic performance of radiologists for the differential diagnosis of thyroid nodules.