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Detection and characterization of small superficially located focal liver lesions by contrast-enhanced ultrasound with high frequency transducers.

Abstract：

AIM:To evaluate the benefits of contrast-enhanced ultrasound (CEUS) with high frequency transducers in the detection and characterization of small superficially located focal liver lesions (FLLs). MATERIAL AND METHODS:From January 2015 to October 2016, 27 superficial FLLs detected by MRI were examined, first with the low frequency convex transducer (1-5 MHz) and afterwards with a high frequency transducer (7.5-12 MHz). High frequency dynamic CEUS was performed after a bolus injection of 2.4 ml SonoVue®. FLLs were confirmed by histopathology after surgery (n=18) or ultrasound guided 18-gauge core-needle biopsy (n=8), or by MRI follow-up (n =1). RESULTS:The mean diameter of FLLs was 10.5±3.1 mm, and meandepth was 6.2±5.3 mm. While using a high frequency transducerthe detection rate of FLLs (100%, 27/27) was significantly higher than low frequency transducer (25.9%, 7/27) (p<0.05). The overall sensitivity, specificity and diagnostic accuracy were significantly improved by CEUS with a high frequency transducer (sensitivity 88.9%; specificity 92.6%; accuracy 96.2%). CONCLUSION:Combining CEUS with the performance of high-frequency transducers is a promising technique to improve the detection and accurate diagnosis of small and superficial FLLs appearing indistinctive on BMUS.

journal_name

Med Ultrason

journal_title

Medical ultrasonography

authors

Wang WP,Dong Y,Cao J,Mao F,Xu Y,Si Q,Dietrich CF

doi

10.11152/mu-1276

subject

Has Abstract

pub_date

2017-11-29 00:00:00

pages

349-356

issue

4

eissn

1844-4172

issn

2066-8643

journal_volume

19

pub_type

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