Acute disseminated encephalomyelitis in a COVID-19 pediatric patient.

Abstract:

:The authors present a case of acute disseminated encephalomyelitis in a COVID-19 pediatric patient with positive SARS-CoV2 markers from a nasopharyngeal swab. A previously healthy 12-year-old-girl presented with a skin rash, headache, and fever. Five days after that, she had an acute, progressive, bilateral, and symmetrical motor weakness. She evolved to respiratory failure. Magnetic resonance imaging (MRI) of the brain and cervical spine showed extensive bilateral and symmetric restricted diffusion involving the subcortical and deep white matter, a focal hyperintense T2/FLAIR lesion in the splenium of the corpus callosum with restricted diffusion, and extensive cervical myelopathy involving both white and gray matter. Follow-up examinations of the brain and spine were performed 30 days after the first MRI examination. The images of the brain demonstrated mild dilatation of the lateral ventricles and widespread widening of the cerebral sulci, complete resolution of the extensive white matter restricted diffusion, and complete resolution of the restricted diffusion in the lesion of the splenium of the corpus callosum, leaving behind a small gliotic focus. The follow-up examination of the spine demonstrated nearly complete resolution of the extensive signal changes in the spinal cord, leaving behind scattered signal changes in keeping with gliosis. She evolved with partial clinical and neurological improvement and was subsequently discharged.

journal_name

Neuroradiology

journal_title

Neuroradiology

authors

de Miranda Henriques-Souza AM,de Melo ACMG,de Aguiar Coelho Silva Madeiro B,Freitas LF,Sampaio Rocha-Filho PA,Gonçalves FG

doi

10.1007/s00234-020-02571-0

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

141-145

issue

1

eissn

0028-3940

issn

1432-1920

pii

10.1007/s00234-020-02571-0

journal_volume

63

pub_type

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