Hypophysitis: A Rare Cause of Impaired Consciousness in a Middle-Aged Woman.

Abstract:

Background:Hypophysitis occurs predominantly in women, usually during pregnancy or postpartum period. Hypophysitis involving the anterior pituitary often presents with adrenal insufficiency. Design/Methods:We describe a 43-year-old woman who presented with recurrent episodes of alteration of sensorium due to hyponatremia. She had a 3-month history of amenorrhea and on evaluation had evidence of pan-hypopituitarism. The magnetic resonance images of the brain showed mild pituitary enlargement and thickened pituitary stalk with homogenous contrast enhancement indicating hypophysitis. She was treated with oral steroids and thyroxine supplements. She remained asymptomatic at 15-month follow-up on low-dose oral steroids and thyroxine supplements. Results:Hypopituitarism due to hypophysitis resulted in recurrent episodes of hyponatremia in our patient. Conclusion:Our case highlights the importance of a systematic search for the etiology for hyponatremic encephalopathy.

journal_name

Neurol India

journal_title

Neurology India

authors

Baby N,Varghese P,Kunnathuparambil SG,Kuriakose AM

doi

10.4103/0028-3886.299159

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

1214-1216

issue

5

eissn

0028-3886

issn

1998-4022

pii

ni_2020_68_5_1214_299159

journal_volume

68

pub_type

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