Platelet-Rich Plasma: Evolving Role in Plastic Surgery.


BACKGROUND:The use of platelet-rich plasma has emerged as one of the most desired nonsurgical treatments for facial rejuvenation and hair restoration. It has grown to encompass a wide variety of applications within the field of plastic surgery, including its use in combination with microneedling, laser, and fat-grafting procedures. METHODS:In this article, the authors aim to (1) describe the preparation process of platelet-rich plasma; (2) discuss the proposed science behind platelet-rich plasma with regard to its evolving role in hair restoration and facial rejuvenation; and (3) highlight the recent literature examining its widespread use. RESULTS:Based on the available literature, there is a therapeutic advantage to the use of platelet-rich plasma as a single treatment modality for alopecia and skin rejuvenation and in combination with laser skin treatment and fat grafting. There is, however, a considerable amount of variability in the processing, preparation, and treatment modalities. CONCLUSIONS:Despite a lack of standardized protocols for platelet-rich plasma preparation and a scarcity of large-scale studies with long-term follow-up, there is convincing evidence with objective measurement modalities that display positive outcomes after treatment for skin rejuvenation, hair regrowth, wound healing, and fat graft take.


Plast Reconstr Surg


Chamata ES,Bartlett EL,Weir D,Rohrich RJ




Has Abstract


2021-01-01 00:00:00














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    abstract::The inframammary fold is a defining element in the shape and structure of the female breast. It should be preserved whenever possible in ablative procedures and recreated accurately when the breast is reconstructed after mastectomy. To date, no accurate anatomic description of this essential structure exists. Previous...

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    pub_type: 杂志文章


    authors: Muntan CD,Sundine MJ,Rink RD,Acland RD

    更新日期:2000-02-01 00:00:00

  • Autoderm: an alternative bioprosthetic for breast reconstruction.

    abstract::The widespread use of bioprosthetic mesh in breast reconstruction has revealed an increased risk of seroma and infection, and a high financial cost. This study introduces a technique that mitigates these shortcomings using an autologous dermal graft (Autoderm). Indications, operative technique, and 1-year outcomes are...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Selber JC,Clemens MW,Oates S,Baumann DP

    更新日期:2013-05-01 00:00:00

  • Evaluation of plastic surgery training programs: integrated/combined versus independent.

    abstract:BACKGROUND:The authors aimed to differentiate between combined/integrated and independent (traditional) methods of plastic surgery training with regard to quality of trainees, caliber of graduates, and practice or career outcomes once graduated. METHODS:To compare combined/integrated with independent residency program...

    journal_title:Plastic and reconstructive surgery

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    authors: Roostaeian J,Fan KL,Sorice S,Tabit CJ,Liao E,Rahgozar P,Tanna N,Bradley JP

    更新日期:2012-07-01 00:00:00

  • Anatomical study of the medial crura and the effect on nasal tip projection in open rhinoplasty.

    abstract:BACKGROUND:Common variations in morphology of the medial crura have been described. The authors' observation is that changes in nasal tip projection depend on the shape and strength of the medial crura. The authors investigated how differences in medial crura shape affect tip projection after surgical intervention. ME...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Patel KB,Mendonca DA,Skolnick G,Woo AS

    更新日期:2013-10-01 00:00:00

  • Applied anatomy of the anterolateral femoral flap.

    abstract::A study of the source of the blood supply to the anterolateral femoral flap was carried out on 42 lower limbs of adult cadavers (among them 35 cadavers with injection of red latex and 1 with india ink into the arteries and 6 vascular cast specimens), and the surface locations of the vascular pedicle were detected on 5...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Xu DC,Zhong SZ,Kong JM,Wang GY,Liu MZ,Luo LS,Gao JH

    更新日期:1988-08-01 00:00:00

  • A functional magnetic resonance imaging paradigm to identify distinct cortical areas of facial function: a reliable localizer.

    abstract:BACKGROUND:Irreversible facial paralysis can be surgically treated by importing both a new neural and a new motor muscle supply. Various donor nerves can be used. If a nerve supply other than the facial nerve is used, the patient has to adapt to generate a smile. If branches of the fifth cranial nerve are used, the pat...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Romeo M,Vizioli L,Breukink M,Aganloo K,Lao J,Cotrufo S,Caldara R,Morley S

    更新日期:2013-04-01 00:00:00

  • Cost analysis of conventional face reconstruction versus face transplantation for large tissue defects.

    abstract:BACKGROUND:Large facial tissue defects are traditionally treated with staged conventional reconstruction. Facial allograft transplantation has emerged as a treatment modality. Facial allografts are procured from a dead donor and transplanted to the recipient. Recipients are then subjected to lifelong global immunosuppr...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Nguyen LL,Naunheim MR,Hevelone ND,Diaz-Siso JR,Hogan JP,Bueno EM,Caterson EJ,Pomahac B

    更新日期:2015-01-01 00:00:00

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    abstract::This case report describes a new method of unipolar transfer of the latissimus dorsi for restoration of elbow flexion. The advantages of the technique are that it has superior resting tension compared to other unipolar transfers and provides more extensive soft-tissue coverage at the elbow than other unipolar or bipol...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Mordick TG 2nd,Britton EN,Brantigan C

    更新日期:1997-05-01 00:00:00

  • Reconstruction of infant thoracic wounds.

    abstract::From 1985 through 1987, five of eight infants with thoracic wounds at Yale-New Haven Hospital underwent chest-wall reconstruction. In total, the eight infants underwent 17 procedures (including multiple open resuscitations) exclusive of the reconstructive operations. Patients undergoing reconstruction ranged from 1 to...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Stahl RS,Kopf GS

    更新日期:1988-12-01 00:00:00

  • Clinical applications of free soleus and peroneal perforator flaps.

    abstract::Clinical applications of two free lateral leg perforator flaps are described: a free soleus perforator flap that is based on the musculocutaneous perforator vessels from one of the three main arteries in the proximal lateral lower leg, and a free peroneal perforator flap that is based on the septocutaneous or direct s...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Kawamura K,Yajima H,Kobata Y,Shigematsu K,Takakura Y

    更新日期:2005-01-01 00:00:00

  • Autologous fat graft in nipple reconstruction.

    abstract::Reconstruction of the nipple is the penultimate step in breast reconstruction after mastectomy. A number of reconstructive techniques have been described for nipple reconstruction including skin grafts, composite grafts, and various local flaps. The authors' preferred reconstructive technique is the local C-V or modif...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Bernard RW,Beran SJ

    更新日期:2003-09-15 00:00:00

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    abstract::The pinwheel flap with a snug barrier areola graft appears to be an efficacious modification of Little's quadripod flap for nipple reconstruction. Further, long-term evaluation is needed to test the validity of these observations over several years. ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Cohen IK,Ward JA,Chandrasekhar B

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  • Quality of life and disease-specific functional status following microvascular reconstruction for advanced (T3 and T4) oropharyngeal cancers.

    abstract::In an effort to evaluate quality-of-life benefits of ablative head and neck cancer surgery and microvascular reconstruction, a longitudinal study was undertaken in which patients with T3 or T4 oropharyngeal cancers without systemic metastases at presentation were administered both general and disease-specific quality-...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Netscher DT,Meade RA,Goodman CM,Alford EL,Stewart MG

    更新日期:2000-04-01 00:00:00

  • Method for intraoperative positioning of the nipple-areola complex in vertical scar reduction mammaplasty.

    abstract::The desired shape and position of the nipple-areola complex may be difficult to achieve in vertical scar reduction mammaplasty when using the standard technique of preoperative marking of the so-called mosque-shaped areolar pattern of excision. We describe our modified approach of intraoperative final positioning of t...

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    authors: Vogt PM,Mühlberger T,Torres A,Peter FW,Steinau HU

    更新日期:2000-05-01 00:00:00

  • The use of a fascial flap in ear reconstruction.

    abstract::We describe the use of a fascial flap for covering the framework in ear reconstruction. When covered in turn with a skin graft, this fascial flap provides an abundant amount of a thin, tough, vascular, hairless cover of good quality in all cases except those where injuries in the auricular area have been deep enough t...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Tegtmeier RE,Gooding RA

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    abstract::Fibrin glue was applied at the anastomotic site of the vein graft that was placed in rat femoral artery defects by the telescoping anastomotic technique at both proximal and distal anastomoses. All 35 vein grafts thus placed were patent, yielding a statistically higher patency rate than those placed in the same femora...

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    pub_type: 杂志文章


    authors: Saitoh S,Nakatsuchi Y

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    abstract::Low-energy lasers are currently being used in the therapy of rheumatoid arthritis, chronic pain, muscle strain, and the promotion of wound healing in human and veterinary medicine. This study examined the effects of low-energy laser on skin-flap survival in a controlled interspecies study using the rat and porcine mod...

    journal_title:Plastic and reconstructive surgery

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    authors: Smith RJ,Birndorf M,Gluck G,Hammond D,Moore WD

    更新日期:1992-02-01 00:00:00

  • Reaction to injectable collagen: results in animal models and clinical use.

    abstract::Since its commercial release, Zyderm collagen implant has been used to treat more than 200,000 subjects in the United States for soft-tissue contour defects and more than 250,000 patients internationally (including the United States). Approximately 3 percent of subjects' skin tested with Zyderm collagen experience loc...

    journal_title:Plastic and reconstructive surgery

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    authors: DeLustro F,Smith ST,Sundsmo J,Salem G,Kincaid S,Ellingsworth L

    更新日期:1987-04-01 00:00:00

  • Platelet-Rich Plasma Influences Expansion and Paracrine Function of Adipose-Derived Stromal Cells in a Dose-Dependent Fashion.

    abstract:BACKGROUND:Lipofilling is a treatment modality to restore tissue volume. Both platelet-rich plasma and adipose-derived stromal cells have been reported to augment the efficacy of lipofilling, yet results are not conclusive. The authors hypothesized that the variation reported in literature is caused by a dose-dependent...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Willemsen JCN,Spiekman M,Stevens HPJ,van der Lei B,Harmsen MC

    更新日期:2016-03-01 00:00:00

  • Remote Ischemic Conditioning Improves Blood Flow and Oxygen Saturation in Pedicled and Free Surgical Flaps.

    abstract:BACKGROUND:Surgical flaps have become safe and reliable reconstructive tools, but total flap loss rates as high as 25 percent and partial flap loss rates as high as 36 percent have been reported due to insufficient perfusion. Therefore, a reliable, noninvasive, and effective way to improve the microcirculation of surgi...

    journal_title:Plastic and reconstructive surgery

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    authors: Kolbenschlag J,Sogorski A,Kapalschinski N,Harati K,Lehnhardt M,Daigeler A,Hirsch T,Goertz O

    更新日期:2016-11-01 00:00:00

  • Utility of screening for obstructive sleep apnea syndrome in children with craniofacial disorders.

    abstract:BACKGROUND:Children with craniofacial disorders are at increased risk for obstructive sleep apnea syndrome. Methods for diagnosing obstructive sleep apnea syndrome in this population remain controversial. Sleep studies are the criterion standard but are impractical for all patients. The utility of obstructive sleep apn...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Cielo CM,Silvestre J,Paliga JT,Maguire M,Gallagher PR,Marcus CL,Taylor JA

    更新日期:2014-09-01 00:00:00

  • Rat mandibular distraction osteogenesis: Part I. Histologic and radiographic analysis.

    abstract::The application of distraction osteogenesis to craniofacial surgery has altered the approach and treatment of congenital and acquired craniofacial defects. Although the histologic and ultrastructural changes associated with distraction osteogenesis have been described extensively, relatively little is known about the ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Rowe NM,Mehrara BJ,Dudziak ME,Steinbreck DS,Mackool RJ,Gittes GK,McCarthy JG,Longaker MT

    更新日期:1998-11-01 00:00:00

  • Cranioplasty in the growing canine skull using demineralized perforated bone.

    abstract::This study was designed to test the hypothesis that demineralized perforated bone matrix implant from canine skull and tibia induces new bone formation within the calvarial defect comparable with the bone induced by autogenous graft. We also were interested in determining whether demineralized perforated bone matrix i...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Salyer KE,Bardach J,Squier CA,Gendler E,Kelly KM

    更新日期:1995-09-01 00:00:00

  • Prospective Evaluation of Obese Patients Undergoing Autologous Abdominal Free Flap Breast Reconstruction.

    abstract:BACKGROUND:Obesity has been viewed as a relative contraindication against autologous free flap breast reconstruction because of increased risks of complications, including flap loss. METHODS:The authors conducted a prospective analysis of obese patients undergoing autologous breast reconstruction. RESULTS:Overall, 72...

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    authors: Chang EI,Liu J

    更新日期:2018-08-01 00:00:00

  • Distal arteriovenous fistula to maintain patency of the venous drainage of a latissimus dorsi flap following subclavian vein repair.

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    authors: Har-Shai Y,Karmeli R,Saute M,Mayblum S,Taran A,Barak A,Loberman Z,Naveh U,Eyal A,Schramek A

    更新日期:2001-02-01 00:00:00

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    authors: Swartz WM,Izquierdo R,Miller MJ

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  • Breast reshaping following massive weight loss: principles and techniques.

    abstract:SUMMARY:Management of the breast following massive weight loss for both reconstructive and aesthetic reasons poses unique challenges that are often inadequately addressed with traditional techniques. The breast mound is often unstable and deflated, with a loose inelastic skin envelope and ill-defined boundaries that bl...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审


    authors: Losken A

    更新日期:2010-09-01 00:00:00

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    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Millard DR Jr,Slepyan DH

    更新日期:1977-04-01 00:00:00

  • An examination of the phenol-croton oil peel: part IV. Face peel results with different concentrations of phenol and croton oil.

    abstract::In Part IV of this examination of the phenol-croton oil peel, the author presents peeling solutions using phenol in concentrations between 16% and 50% as the carrier for croton oil. Previously, in Part I, the author showed that phenol alone in concentrations of less than 50% has no significant peeling effect on the sk...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Hetter GP

    更新日期:2000-03-01 00:00:00

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    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Cho BC

    更新日期:2004-10-01 00:00:00