A comparative trial of cefazolin and moxalactam as prophylaxis for preventing infection after abdominal hysterectomy.

Abstract:

:In a randomized, double-blind clinical trial, 208 women who underwent abdominal hysterectomy received either cefazolin (N = 108) or moxalactam (N = 100) as perioperative antimicrobial prophylaxis. There were no differences between the two groups in rates of serious infection, minor wound infection, standard febrile morbidity, duration of hospitalization, proportion receiving other postoperative antibiotics, or rates of rehospitalization. Women who received moxalactam had significantly more urinary tract infections, 87% of which were caused by the enterococcus. It is concluded that perioperative prophylaxis with third-generation cephalosporins is not justified at this time.

journal_name

Obstet Gynecol

authors

Tuomala RE,Fischer SG,Muñoz A,Souney PF,Steele L,Polk BF

subject

Has Abstract

pub_date

1985-09-01 00:00:00

pages

372-6

issue

3

eissn

0029-7844

issn

1873-233X

journal_volume

66

pub_type

临床试验,杂志文章,随机对照试验
  • Transfer of inflammatory cytokines across the placenta.

    abstract:OBJECTIVE:The purpose of this study was to determine whether the placental transfer of interleukin (IL)-1alpha, IL-6, and tumor necrosis factor-alpha (TNF-alpha) occurs. METHODS:Four normal-term placentas were perfused for maternal-fetal transfer of the cytokines, 2 placentas for fetal-maternal transfer, and 4 additio...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000114980.40445.83

    authors: Zaretsky MV,Alexander JM,Byrd W,Bawdon RE

    更新日期:2004-03-01 00:00:00

  • Interbirth interval with frequency of cesarean delivery.

    abstract:OBJECTIVE:To estimate whether and to what extent interbirth interval is associated with cesarean delivery. METHODS:This is a retrospective cohort study of 2,528 multiparous women who presented to labor and delivery at a single tertiary care obstetric hospital during an 18-month period. Women were grouped by their inte...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31821c4368

    authors: Miller ES,Grobman WA

    更新日期:2011-07-01 00:00:00

  • Prolactin hypersecretion and short luteal phase defects.

    abstract::The short luteal phase is commonly found in ovulating women presenting with infertility, or in amenorrheic women induced to ovulate with clomiphene. When the short luteal phase defect is accompanied by the discovery of galactorrhea, the two abnormalities may share a common underlying cause. Two cases are presented to ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Corenblum B,Pairaudeau N,Shewchuk AB

    更新日期:1976-04-01 00:00:00

  • The relationship of amniotic fluid cytokines and preterm delivery, amniotic fluid infection, histologic chorioamnionitis, and chorioamnion infection.

    abstract:OBJECTIVE:To assess the association between cytokines in the amniotic fluid (AF) and preterm delivery, the isolation of bacteria from the AF or chorioamnion, and histologic chorioamnionitis. METHODS:Fifty afebrile women with intact membranes in preterm labor at or before 34 weeks' gestation underwent amniocentesis. Cy...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Hillier SL,Witkin SS,Krohn MA,Watts DH,Kiviat NB,Eschenbach DA

    更新日期:1993-06-01 00:00:00

  • Occult Uterine Sarcoma and Leiomyosarcoma: Incidence of and Survival Associated With Morcellation.

    abstract:OBJECTIVE:To estimate the incidence of occult uterine sarcoma and leiomyosarcoma in hysterectomies for leiomyomas and the risk associated with their morcellation. METHODS:We conducted a population-based cohort study. All uterine sarcomas from 2006-2013 in an integrated health care system were identified. Age- and race...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001187

    authors: Raine-Bennett T,Tucker LY,Zaritsky E,Littell RD,Palen T,Neugebauer R,Axtell A,Schultze PM,Kronbach DW,Embry-Schubert J,Sundang A,Bischoff K,Compton-Phillips AL,Lentz SE

    更新日期:2016-01-01 00:00:00

  • Role of antibiotic prophylaxis in retropubic surgery for stress urinary incontinence.

    abstract::The effectiveness of prophylactic antibiotics was studied prospectively in 26 women undergoing retropubic urethropexy for genuine stress incontinence. Each of the 14 patients in the antibiotic prophylaxis group received three 1-g doses of intravenous cefazolin administered before, during, and 6-8 hours after surgery. ...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Bhatia NN,Karram MM,Bergman A

    更新日期:1989-10-01 00:00:00

  • Influence of Lymphadenectomy on Survival for Early-Stage Endometrial Cancer.

    abstract:OBJECTIVE:To use a number of methods to control for confounding and selection bias to examine the association between lymphadenectomy and survival in a large cohort of women with endometrial cancer. METHODS:A retrospective cohort study using the National Cancer Data Base was performed to identify women with endometrio...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001194

    authors: Wright JD,Huang Y,Burke WM,Tergas AI,Hou JY,Hu JC,Neugut AI,Ananth CV,Hershman DL

    更新日期:2016-01-01 00:00:00

  • Adenomyosis: symptoms, histology, and pregnancy terminations.

    abstract:OBJECTIVE:To correlate symptoms of uterine adenomyosis with histopathologic features. METHODS:One hundred eleven specimens of uteri and cervices that weighed under 280 g were reevaluated. When adenomyosis was identified, assessment included depth of adenomyotic foci, graded as deep (above 80%), intermediate (40-80%), ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(99)00659-6

    authors: Levgur M,Abadi MA,Tucker A

    更新日期:2000-05-01 00:00:00

  • Relaxin secretion in early pregnancy.

    abstract::Relaxin is a peptide hormone produced solely by the corpus luteum of pregnant women. Extracts of human pregnancy corpora lutea have relaxin activity in bioassay systems. This activity can be measured in a heterologous porcine radioimmunoassay (RIA). Immunoreactive relaxin was undetectable in the RIA in 51 nonpregnant ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Quagliarello J,Steinetz BG,Weiss G

    更新日期:1979-01-01 00:00:00

  • ACOG committee opinion no. 561: Nonmedically indicated early-term deliveries.

    abstract::For certain medical conditions, available data and expert opinion support optimal timing of delivery in the late-preterm or early-term period for improved neonatal and infant outcomes. However, for nonmedically indicated early-term deliveries such an improvement has not been demonstrated. Morbidity and mortality rates...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000428649.57622.a7

    authors:

    更新日期:2013-04-01 00:00:00

  • Alerting pregnant women to the risk of reptile-associated salmonellosis.

    abstract:BACKGROUND:Reptile- and amphibian-associated salmonellosis poses significant risk to infants and young children. The Centers for Disease Control and Prevention has advised that reptiles and amphibians should not be kept in households with children younger than 5 years old. CASE:We report a 5-day-old newborn with Salmo...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000187950.37065.87

    authors: Milstone AM,Agwu AG,Angulo FJ

    更新日期:2006-02-01 00:00:00

  • Hormones, mood, and cognitive functioning in postmenopausal women.

    abstract::Findings from basic neuroscience have provided information on the effects of estrogen on brain morphology and chemistry that explain how this sex steroid may influence brain function. The clinical literature shows that estrogen enhances mood and specific aspects of cognitive functioning in postmenopausal women. There ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00431-9

    authors: Sherwin BB

    更新日期:1996-02-01 00:00:00

  • Persistent right umbilical vein: sonographic detection and subsequent neonatal outcome.

    abstract:OBJECTIVE:To review our experience with antenatal detection and subsequent neonatal outcome of fetuses with a persistent right umbilical vein. METHODS:In a prospective observational study, 33 cases of persistent right umbilical vein were detected during 15,237 obstetric ultrasound examinations performed after 15 weeks...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Hill LM,Mills A,Peterson C,Boyles D

    更新日期:1994-12-01 00:00:00

  • Ability of normal vaginal flora to produce detectable phosphatidylglycerol in amniotic fluid in vitro.

    abstract:OBJECTIVE:To determine if bacteria are capable of producing phosphatidylglycerol in amniotic fluid (AF) and the number of colony forming units (CFU) of bacteria necessary to produce this result. METHODS:Eleven species of bacteria and one species of yeast, common to the female genital tract and implicated in chorioamni...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00032-m

    authors: Lambers DS,Brady K,Leist PA,Setser C,Helmchen R

    更新日期:1995-05-01 00:00:00

  • Perinatal and neonatal outcome and late pulmonary sequelae in infants born after preterm premature rupture of membranes.

    abstract:OBJECTIVE:To evaluate fetal outcome and long-term impact of very early preterm premature rupture of membranes (PROM). METHODS:In a retrospective cohort study, 78 women with singleton pregnancies who delivered at the Oulu University Central Hospital between 1990 and 1996 and who had early PROM, between the 17th and 30t...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00213-0

    authors: Kurkinen-Räty M,Koivisto M,Jouppila P

    更新日期:1998-09-01 00:00:00

  • Use of the progestogen challenge test to reduce the risk of endometrial cancer.

    abstract::In contrast to several retrospective studies reporting an increased risk of endometrial cancer during the mid-1970s, especially in estrogens.gen-treated postmenopausal women, the number of cancers at Wilford Hall USAF Medical Center has steadily declined despite continued estrogen use. In a 4-year study from 1975 to 1...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Gambrell RD Jr,Massey FM,Castaneda TA,Ugenas AJ,Ricci CA,Wright JM

    更新日期:1980-06-01 00:00:00

  • Laser therapy of genital condylomata acuminata.

    abstract::The effectiveness of the carbon dioxide laser was evaluated in the treatment of penile, anorectal, and urethral condylomata acuminata in 40 men. All but six cases of urethral condylomata were prior conventional treatment failures. Postlaser follow-up ranged between one and two years, with an average of 16 months. No p...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ferenczy A

    更新日期:1984-05-01 00:00:00

  • 13CO2 isotopic laser used through the operating channel of laser laparoscopes: a comparative study of power and energy density losses.

    abstract:OBJECTIVE:To evaluate the power transmission, spot size, power density, and energy density of a new isotopic carbon dioxide (13CO2) laser compared with a conventional CO2 laser. METHODS:Experiments were performed in a laboratory using a conventional CO2 laser and an isotopic 13CO2 laser. Two laparoscopes with 5-mm and...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Adamson GD,Reich H,Trost D

    更新日期:1994-05-01 00:00:00

  • Outpatient treatment of acute pyelonephritis in pregnancy after 24 weeks.

    abstract:OBJECTIVE:To compare outpatient to inpatient management of acute pyelonephritis in pregnancy beyond 24 weeks' gestation. METHODS:Ninety-two gravidas past 24 weeks' gestation, randomized to outpatient or inpatient therapy, received two 1-g doses of intramuscular ceftriaxone at 24-hour intervals while hospitalized, then...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0029-7844(99)00386-5

    authors: Wing DA,Hendershott CM,Debuque L,Millar LK

    更新日期:1999-11-01 00:00:00

  • Effectiveness of treatment strategies of some women with pelvic inflammatory disease: a randomized trial.

    abstract:OBJECTIVE:Among all women with pelvic inflammatory disease (PID), prevention of adverse reproductive consequences appears to be similarly achieved by outpatient treatment and inpatient treatment. We assessed whether outpatient is as effective as inpatient treatment in relevant age, race, and clinical subgroups of women...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.AOG.0000175193.37531.6e

    authors: Ness RB,Trautmann G,Richter HE,Randall H,Peipert JF,Nelson DB,Schubeck D,McNeeley SG,Trout W,Bass DC,Soper DE

    更新日期:2005-09-01 00:00:00

  • Elevated maternal serum alpha-fetoprotein with oligohydramnios: ultrasound evaluation and outcome.

    abstract::Nineteen pregnancies evaluated for elevated maternal serum alpha-fetoprotein levels were found to have moderate to severe oligohydramnios. There were no survivors among six fetuses with ultrasound-diagnosed urinary tract anomalies. We followed 11 of the remaining 13 pregnancies with serial ultrasound examinations. Whe...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Richards DS,Seeds JW,Katz VL,Lingley LH,Albright SG,Cefalo RC

    更新日期:1988-09-01 00:00:00

  • Erb/Duchenne's palsy: a consequence of fetal macrosomia and method of delivery.

    abstract::Methods of delivery, maternal and neonatal characteristics were examined to determine their role in the occurrence of Erb/Duchenne's palsy. Data from 210,947 Washington state birth certificates from 1980 through 1982 were examined. The incidence was 50.2 cases of Erb's palsy per 100,000 live births. A case control stu...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: McFarland LV,Raskin M,Daling JR,Benedetti TJ

    更新日期:1986-12-01 00:00:00

  • Transcutaneous electrical nerve stimulation (TENS) for the treatment of primary dysmenorrhea: a randomized crossover comparison with placebo TENS and ibuprofen.

    abstract::In a randomized four-way crossover study, 32 women with primary dysmenorrhea were treated with transcutaneous electrical nerve stimulation (TENS) for two cycles, placebo (sham) TENS for one cycle, or ibuprofen 400 mg four times a day for one cycle. The TENS setting used was 100 pulses per second with 100-microsecond p...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Dawood MY,Ramos J

    更新日期:1990-04-01 00:00:00

  • Avoiding transmitting identified mutations to offspring using preimplantation genetic diagnosis.

    abstract:BACKGROUND:Preimplantation genetic diagnosis has been used to decrease or avoid the risk of transmitting identified mutations to offspring. CASE:A 29-year-old woman with spondyloepiphyseal dysplasia congenita and her 30-year-old husband with Marfan syndrome underwent in vitro fertilization with preimplantation genetic...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181c9b316

    authors: Smith LP,Hughes MR,Thirumoorthi I,Proud VK,Penzias AS

    更新日期:2010-02-01 00:00:00

  • Improved survival of Asians with corpus cancer compared with whites: an analysis of underlying factors.

    abstract:OBJECTIVE:To compare the clinicopathologic prognosticators and survival of Asians and whites with corpus cancer. METHODS:Demographic, clinicopathologic, and survival data were obtained from the 1992-2001 Surveillance, Epidemiology, and End Results Program. Statistical analyses were performed by Kaplan-Meier methods an...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000195062.75199.7d

    authors: Zhang MM,Cheung MK,Osann K,Lee MM,Gomez SS,Whittemore AS,Husain A,Teng NN,Chan JK

    更新日期:2006-02-01 00:00:00

  • Maternal serum levels of placental protein 5 in complications of late pregnancy.

    abstract::Maternal serum levels of placental protein 5 (PP5) were measured during the third trimester in women with normal and abnormal pregnancies. PP5 levels were significantly elevated in patients with preeclampsia, diabetes, intrauterine growth retardation associated with preeclampsia, and twin pregnancy. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Salem HT,Westergaard JG,Hindersson P,Lee JN,Grudzinskas JG,Chard T

    更新日期:1982-04-01 00:00:00

  • Effect of parity on sexual function: an identical twin study.

    abstract:OBJECTIVE:To assess the impact of childbirth on female sexual function by using an identical twin study design. METHODS:A survey including the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) was administered to 542 twin sisters, and PISQ-12 scores of 29 twin pairs discordant for parity were c...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000207677.03235.76

    authors: Botros SM,Abramov Y,Miller JJ,Sand PK,Gandhi S,Nickolov A,Goldberg RP

    更新日期:2006-04-01 00:00:00

  • Risk of cervical stenosis after large loop excision or laser conization.

    abstract:OBJECTIVE:To assess the frequency of cervical stenosis in patients treated by laser conization or the loop electrosurgical excision procedure and to determine the preoperative and therapeutic factors associated with its occurrence. METHODS:Two hundred fifty-five women treated by laser conization and 277 treated by loo...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/S0029-7844(96)00331-6

    authors: Baldauf JJ,Dreyfus M,Ritter J,Meyer P,Philippe E

    更新日期:1996-12-01 00:00:00

  • Vaginal evisceration long after vaginal hysterectomy.

    abstract:BACKGROUND:Vaginal evisceration can take place many years after vaginal surgery. CASE:An 87-year-old woman presented with evisceration of small bowel through the vagina, 15 years after she underwent a vaginal hysterectomy. On physical examination, her vital signs were normal. Forty centimeters of small bowel was visib...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(02)02336-0

    authors: Feiner B,Lissak A,Kedar R,Lefel O,Lavie O

    更新日期:2003-05-01 00:00:00

  • Fertility sparing treatment for in situ and early invasive adenocarcinoma of the cervix.

    abstract:OBJECTIVE:To explore the outcome and long-term follow-up of fertility sparing surgery for cervical adenocarcinoma in situ and early invasive adenocarcinoma. METHODS:Between 1985 and 1996, all women with adenocarcinoma in situ (AIS) and stage I adenocarcinoma were identified. Data were abstracted from clinical records ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(01)01544-7

    authors: McHale MT,Le TD,Burger RA,Gu M,Rutgers JL,Monk BJ

    更新日期:2001-11-01 00:00:00