Spatio-temporal integration in the substrate for self-stimulation of the prefrontal cortex.

Abstract:

:The number of stimulation pulses required to maintain a half maximal rate of self-stimulation of the prefrontal cortex (PFC) was determined for various currents. Over a restricted range, the effects of decreasing the stimulation frequency could be compensated for by increasing the current. This finding cannot easily be reconciled with the hypothesis that the rewarding impact of PFC stimulation is unaffected by increments in current. The minimum current that would support self-stimulation of the PFC at high frequencies was larger than has been reported at medial forebrain bundle sites.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Schenk S,Prince C,Shizgal P

doi

10.1016/0031-9384(85)90353-1

subject

Has Abstract

pub_date

1985-08-01 00:00:00

pages

303-6

issue

2

eissn

0031-9384

issn

1873-507X

pii

0031-9384(85)90353-1

journal_volume

35

pub_type

杂志文章
  • Malaise can condition avoidance of high-viscosity fluids.

    abstract::Previous researchers have assumed that malaise-inducing drugs condition aversions to tastes more readily than to textural stimuli. The present report shows that rats given a single injection of lithium chloride after they have sampled a viscous fluid, subsequently showed greater avoidance of that fluid than did contro...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90373-a

    authors: Ramirez I

    更新日期:1992-11-01 00:00:00

  • Concentration-dependent licking of sucrose and sodium chloride in rats with parabrachial gustatory lesions.

    abstract::The medial zone of parabrachial nuclei (PBN) serves as an obligatory synapse in the central gustatory system in rodents. Lesions in the PBN impair taste aversion learning and depletion-induced sodium appetite in rats, and also alter the ingestion of sapid stimuli. Interpretation of these lesion-induced behavioral defi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90205-t

    authors: Spector AC,Grill HJ,Norgren R

    更新日期:1993-02-01 00:00:00

  • Experimental manipulation of breakfast in normal and overweight/obese participants is associated with changes to nutrient and energy intake consumption patterns.

    abstract::The effect of breakfast and breakfast omission on daily food intake in normal and overweight participants was investigated. 37 participants were recruited for this experimental study and assigned to one of four groups on the basis of their body mass index (BMI) (normal weight BMI <25 kg/m(2) or overweight/obese BMI >2...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.05.015

    authors: Reeves S,Huber JW,Halsey LG,Horabady-Farahani Y,Ijadi M,Smith T

    更新日期:2014-06-22 00:00:00

  • Predator odor exposure increases food-carrying behavior in rats.

    abstract::To cover their energy demands, prey animals are forced to search for food. However, during foraging they also expose themselves to the risk of becoming the prey of predators. Consequently, in order to increase their fitness foraging animals have to trade-off efficiency of foraging against the avoidance of predation ri...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.11.005

    authors: Wernecke KE,Brüggemann J,Fendt M

    更新日期:2016-02-01 00:00:00

  • Effects of lesions to the dorsal noradrenergic bundle on counterconditioning of punished barpressing.

    abstract::The possible contribution of the dorsal noradrenergic bundle (DB) to the development of a simple form of counterconditioning (an associative mechanism leading to behavioural tolerance for stress) was assessed by comparison of the performance of animals with 6-hydroxydopamine-induced lesions of the DB to that of sham-o...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(87)90178-8

    authors: Tsaltas E,Gray JA,Preston GC

    更新日期:1987-01-01 00:00:00

  • Behavioral responses of CD-1 mice to conspecific and heterospecific blood odors and to a blood odor component.

    abstract::The odor of blood may have both aversive and attractive properties for mammals, depending on the species of the odor donor and the species perceiving the odor. To better understand the informational content of blood odor for a prey species we assessed behavioral responses of male CD-1 mice (n=60) to the odor of blood ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.12.006

    authors: Lahger C,Laska M

    更新日期:2018-02-01 00:00:00

  • State-anxiety and low moods: evidence for a single concept.

    abstract::The aim of the study was to examine the Spielberger's hypothesis, according to which changes in state-anxiety level would correspond exactly to adverse changes in mood states. We analyzed the correlation coefficients between state-anxiety and low moods, and further investigated whether these correlation coefficients i...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(01)00575-3

    authors: Bolmont B,Abraini JH

    更新日期:2001-11-01 00:00:00

  • Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice.

    abstract::The present study compared the ability of sweet ageusic T1r3 knockout (KO) and Calhm1 KO mice to acquire preferences for a sucrose-paired flavor as well as for unflavored sucrose. The KO and wildtype (WT) mice were given 24-h one-bottle access to 8% sucrose containing one flavor CS+, e.g., grape) and to water containi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2013.12.003

    authors: Sclafani A,Marambaud P,Ackroff K

    更新日期:2014-03-14 00:00:00

  • Olfactory discrimination and incentive value of non copulating and sexually sluggish male rats.

    abstract::Some apparently healthy male rats fail to copulate despite being tested on repeated occasions with receptive females and are called non copulating (NC) rats. NC rats sniff and lick the female genitals, and show normal erectile and ejaculatory functions and hormonal levels. Sexually sluggish (S) male rats take a long t...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2007.11.027

    authors: De Gasperín-Estrada GP,Camacho FJ,Paredes RG

    更新日期:2008-03-18 00:00:00

  • Hippocampal conditioned responses in the absence of entorhinal input.

    abstract::Hippocampal unit responses to conditioned stimuli were analyzed in intact rats and in rats deprived of the input from the entorhinal cortex to the hippocampus. Cells in normal rats responded more intensely to a conditioned stimulus when it was applied within 1 min from a previous one. The rats with lesions had smaller...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(75)90108-0

    authors: Segal M

    更新日期:1975-09-01 00:00:00

  • Hormonal reactions to fighting in rat colonies: prolactin rises during defence, not during offence.

    abstract::Male Wistar rats living in colonies of 4 males plus 4 females were compared to noncolony males, cohabitating with a female. Irreversible dominance relationships developed between one dominant male (D) and three subordinates (S). Dominants developed high basal testosterone levels and large preputial glands. Subordinate...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90078-g

    authors: Dijkstra H,Tilders FJ,Hiehle MA,Smelik PG

    更新日期:1992-05-01 00:00:00

  • Repeated social defeat stress induces chronic hyperthermia in rats.

    abstract::Psychological stressors are known to increase core body temperature (T(c)) in laboratory animals. Such single stress-induced hyperthermic responses are typically monophasic, as T(c) returns to baseline within several hours. However, studies on the effects of repeated psychological stress on T(c) are limited. Therefore...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2010.04.027

    authors: Hayashida S,Oka T,Mera T,Tsuji S

    更新日期:2010-08-04 00:00:00

  • The influence of exercise on energy balance changes induced by ventromedial hypothalamic lesion in the rat.

    abstract::The effects of a hypothalamic ventromedial area lesion on energy balance were tested in exercising rats and in sedentary rats to add further information about the type of obesity developed after ventromedial lesion. Four groups of six male Sprague-Dawley rats were used. Group 1: sham-lesioned and sedentary rats, which...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90324-9

    authors: Monda M,Amaro S,De Luca B

    更新日期:1993-12-01 00:00:00

  • Sex differences in oxidant/antioxidant balance under a chronic mild stress regime.

    abstract::The deterioration of homeostasis between oxidant/antioxidant species may represent an important mechanism linking psychological stress to cardiovascular risk despite the many sex differences in stress responsiveness. The goal of the present study was to investigate the influence of chronic mild stress (CMS), a widely ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.05.011

    authors: Kamper EF,Chatzigeorgiou A,Tsimpoukidi O,Kamper M,Dalla C,Pitychoutis PM,Papadopoulou-Daifoti Z

    更新日期:2009-08-04 00:00:00

  • Melatonin administrated immediately before an intense exercise reverses oxidative stress, improves immunological defenses and lipid metabolism in football players.

    abstract::Acute sport exercise leads to a strong stimulation of muscle tissue and a change in the organism energy demands. This study was designed to investigate the effect of oral melatonin supplementation on human physiological functions associated with acute exercise. Immune, endocrine and metabolic parameters were measured ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.physbeh.2011.12.015

    authors: Maldonado MD,Manfredi M,Ribas-Serna J,Garcia-Moreno H,Calvo JR

    更新日期:2012-03-20 00:00:00

  • Experimental study on physiological responses and thermal comfort under various ambient temperatures.

    abstract::This study mainly explored the thermal comfort from the perspective of physiology. Three physiological parameters, including skin temperature (local and mean), electrocardiograph (ECG) and electroencephalogram (EEG), were investigated to see how they responded to the ambient temperature and how they were related to th...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2007.09.012

    authors: Yao Y,Lian Z,Liu W,Shen Q

    更新日期:2008-01-28 00:00:00

  • Effects of intracerebroventricular injection of dynorphin, leumorphin and alpha neo-endorphin on operant feeding in pigs.

    abstract::Young pigs, which are useful experimental animals for biomedical research, were prepared with lateral intracerebroventricular (ICV) cannulae and housed individually in cages fitted with operant panels, with food and water ad lib. ICV injection of 200 micrograms of dynorphin A 1-17 or 1-13 resulted in a significant mea...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90233-t

    authors: Baldwin BA,de la Riva C,Ebenezer IS

    更新日期:1990-12-01 00:00:00

  • Seasonal energetics of the Hottentot golden mole at 1500 m altitude.

    abstract::Winter is an energetically stressful period for small mammals as increasing demands for thermoregulation are often coupled with shortages of food supply. In sub-tropical savannah, Hottentot golden moles (Ambysomus hottentottus longiceps) forage throughout the year and for long periods of each day. This may enable them...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.02.022

    authors: Scantlebury M,Oosthuizen MK,Speakman JR,Jackson CR,Bennett NC

    更新日期:2005-04-13 00:00:00

  • Fat, carbohydrate and protein by oral gavage in the rat can be equally effective for satiation.

    abstract::This study aimed to determine the relative efficacy of the macronutrients, protein, fat and carbohydrate to induce satiation and satiety in rats in relation to macronutrient activation of neurons in the nucleus of the solitary tract (NTS). Male Sprague Dawley rats were schedule-fed twice a day for 2 h, receiving 100% ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.04.022

    authors: Cassie N,Anderson R,Wilson D,Mercer JG,Barrett P

    更新日期:2019-08-01 00:00:00

  • Modification of body temperature and sleep state using behavioral conditioning.

    abstract::Previous research has demonstrated the conditionability of events within the acute-phase response. This study examined whether two such responses, fever and sleep alterations, were conditionable in the rat during the dark photoperiod. The experimental animals were administered a novel saccharin solution as the conditi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)00314-9

    authors: Exton MS,Bull DF,King MG,Husband AJ

    更新日期:1995-04-01 00:00:00

  • Frequency-response characteristics provide a functional separation between stimulation-bound feeding and self-stimulation.

    abstract::Many lateral hypothalamic electrodes that support self-stimulation also elicit feeding. Refractory period and conduction velocity estimates for the axons supporting these behaviors appear identical, suggesting that these behaviors may be elicited by stimulation of a common directly activated substrate. However, it is ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90007-q

    authors: Waraczynski MA,Kaplan JM

    更新日期:1990-05-01 00:00:00

  • Facilitation of thermoregulatory heating behavior by single cortical spreading depression in the rat.

    abstract::Effects of single waves of unilateral cortical spreading depression (CSD) on skin-heating behavior were studied in the rat with the unilateral lesion in the preoptic and anterior hypothalamus (PO/AH). A single CSD contralateral to the PO/AH lesion significantly increased the number of heating for 4 min after CSD had e...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:

    authors: Shibata M,Hori T,Kiyohara T,Nakashima T

    更新日期:1983-11-01 00:00:00

  • Photoperiod modulates the effects of steroids on sociosexual behaviors of hamsters.

    abstract::Female hamsters (Mesocricetus auratus) exposed to a short photoperiod for 8 weeks were ovariectomized, as were hamsters that were maintained in a long photoperiod. We then tested the effect of photoperiod on the ability of progesterone (P) to reduce aggression, as well as on the effects of estrogen (E), alone and with...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90307-n

    authors: Elliott AS,Nunez AA

    更新日期:1992-06-01 00:00:00

  • Repeated cocaine treatment activates flank marking in adolescent female hamsters.

    abstract::Cocaine abuse during adolescence represents a significant health risk due to the potential for both acute and long-term negative physical and psychological sequelae, including increased aggressive behavior. This study examined the effect of adolescent cocaine treatment on flank marking (i.e., a stereotypic motor behav...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(01)00478-4

    authors: Melloni RH Jr,Connor DF,Todtenkopf MS,DeLeon KR,Sanyal P,Harrison RJ

    更新日期:2001-07-01 00:00:00

  • Suprachiasmatic lesions eliminate 24-h blood pressure variability in rats.

    abstract::To evaluate whether the suprachiasmatic nuclei (SCN) control 24-h rhythmicity in cardiovascular function, rats were subjected to computerized recording of 24-h blood pressure (BP) and heart rate (HR) following SCN lesions. In sham- and nonlesioned rats, circadian patterns of BP and HR ran in phase with those in feedin...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90138-4

    authors: Janssen BJ,Tyssen CM,Duindam H,Rietveld WJ

    更新日期:1994-02-01 00:00:00

  • Wistar rats allowed to self-select macronutrients from weaning to maturity choose a high-protein, high-lipid diet.

    abstract::The aim of this work was to study the evolution of rat food choice in relation to their age and metabolic parameters. Eighty Wistar rats were studied from birth to 13 weeks of age. At weaning, six litters were fed on a macronutrient self-selecting diet and four on a standard diet. In self-selecting males, protein inta...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(02)00676-5

    authors: Jean C,Fromentin G,Tomé D,Larue-Achagiotis C

    更新日期:2002-05-01 00:00:00

  • Chronic infusion of the amylin antagonist AC 187 increases feeding in Zucker fa/fa rats but not in lean controls.

    abstract::Numerous studies have established the pancreatic B-cell hormone amylin as an important anorectic peptide affecting meal-ending satiety. In the present study, we investigated the effect of a chronic infusion of the amylin antagonist AC 187 on food intake. The studies were performed using obese Zucker fa/fa rats, which ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2004.02.002

    authors: Grabler V,Lutz TA

    更新日期:2004-05-01 00:00:00

  • Effect of cage size on ultradian locomotor rhythms of laboratory mice.

    abstract::The effect of cage size on spontaneous locomotor rhythms of laboratory mice was studied under simulated light-dark (12:12) cycles. On-line image analysis of bodily displacement yielded a locomotor signal over a period of 3 days. Continuous wavelet transform was applied to the signal, and ensemble averaging of eight mi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00305-3

    authors: Poon AM,Wu BM,Poon PW,Cheung EP,Chan FH,Lam FK

    更新日期:1997-12-01 00:00:00

  • A nitric oxide synthase inhibitor, N(G)-nitro-L-arginine methyl ester, attenuates lipoprivic feeding in mice.

    abstract::Possible involvement of nitric oxide (NO) in lipoprivic feeding was investigated in nondeprived male ICR mice adapted to a high-fat diet in a within-subjects design. Lipoprivation was induced by blocking fatty acid oxidation with Na-mercaptoacetate (MA), which produces a short-term increase in feeding in mice and rats...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(03)00220-8

    authors: Czech DA,Kazel MR,Harris J

    更新日期:2003-10-01 00:00:00

  • Neonatal infection modulates behavioral flexibility and hippocampal activation on a Morris Water Maze task.

    abstract::Neonatal infection has enduring effects on the brain, both at the cellular and behavioral levels. We determined the effects of peripheral infection with Escherichia coli at postnatal day (P) 4 in rats on a water maze task in adulthood, and assessed neuronal activation in the dentate gyrus (DG) following the memory tes...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.02.033

    authors: Williamson LL,Bilbo SD

    更新日期:2014-04-22 00:00:00