Abstract:
:This report describes the results of bone marrow leukocyte immunophenotypic studies, DNA index measurement, and chromosome analysis in a newborn with Down syndrome and transient myeloproliferative disorder. The infant's initial leukocytosis with immature cells in the peripheral blood and thrombocytopenia resolved without treatment by 6 months of age, and he was well at 2 years of age. The lack of specific reactivity between the patient's morphologically immature cells and multiple monoclonal antibodies directed against lymphoid and myeloid leukemia cells may be characteristic of this disorder. Other cases should be examined for immunophenotype to correlate the results with chromosomal analysis and to provide a basis for comparison in those who subsequently develop true acute leukemia.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Cook JA,Raney B Jr,Innes DJ Jr,Normansell Ddoi
10.1177/000992288902800306subject
Has Abstractpub_date
1989-03-01 00:00:00pages
132-5issue
3eissn
0009-9228issn
1938-2707journal_volume
28pub_type
杂志文章abstract::Neonatal intensive care unit (NICU) survivors demonstrate handicapping sensorineural hearing loss up to 50 times more frequently than normal newborns, yet little is known about the etiology of the hearing loss. Theoretically, accurate identification and triage of a particular infant based on a clinical profile would b...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289503400304
更新日期:1995-03-01 00:00:00
abstract::With an incidence of 1 in 3,000, neurofibromatosis type 1 (NF1), or von Recklinghausen disease, is one of the most common genetic disorders encountered by primary care physicians. NF1 is a multisystem disease that affects more than one million people worldwide (more than 80,000 in the United States). Although most ped...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992289603501101
更新日期:1996-11-01 00:00:00
abstract::Despite recommendations against routine imaging, chest radiography (CXR) is frequently performed on infants hospitalized for bronchiolitis. We conducted a review of 811 infants hospitalized for bronchiolitis to identify clinical factors associated with imaging findings. CXR was performed on 553 (68%) infants either on...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922817698802
更新日期:2017-10-01 00:00:00
abstract::Between 1979 and 1981, 22 children with osteomyelitis and/or septic arthritis were hospitalized at Soroka University Hospital. Streptococcus pneumoniae was cultured in five of the children, four of whom were under 2 years of age. In four other children under 2 years of age, Haemophilus influenzae was cultured. Staphyl...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400305
更新日期:1985-03-01 00:00:00
abstract::The General Academic Pediatrician (GAP) may act as a consultant to both primary care pediatricians and tertiary care subspecialists. The authors surveyed a consultation service staffed by three GAP's in a tertiary care children's hospital. The service was financially successful and generated new sources of referrals f...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288802701203
更新日期:1988-12-01 00:00:00
abstract::An asymptomatic child with a murmur can be challenging practice management conundrum. Some providers refer all patients with a "new" murmur to a cardiologist, likely resulting in excessive resource utilization and parental anxiety. This study examines whether the prevalence of significant cardiac pathology differs in ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816656623
更新日期:2017-04-01 00:00:00
abstract::Twenty-two pediatric residents and 31 medical students viewed the Play Nicely program. The Play Nicely program is a multimedia program that teaches health care professionals how to counsel parents to use positive parenting and disciplining strategies in response to early childhood aggression. Health care professionals...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816667313
更新日期:2016-10-01 00:00:00
abstract::Premature delivery is common in pregnancies complicated by maternal diabetes. However, the outcome of very-low-birth-weight infants (VLBWI) born to mothers with diabetes is not known. Employing a matched double-cohort design, we investigated the influence of maternal diabetes on the outcome of VLBWI born in Winnipeg f...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280204100705
更新日期:2002-09-01 00:00:00
abstract::The authors compared dipstick tests for leukocyte esterase and nitrite and microscopic examination of urinary sediment with urine culture to assess whether the former tests could reliably rule out bacteriuria in specimens from children. The authors studied urine specimens from 1010 infants and children younger than ag...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900402
更新日期:1990-04-01 00:00:00
abstract::Families of 49 hearing-impaired children responded to a questionnaire requesting information about the identification of their child's hearing loss. Parents were the first to suspect the hearing loss in 48 cases but more often than not were told that the child would outgrow it or was too young to test. When profession...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289103000202
更新日期:1991-02-01 00:00:00
abstract::This study investigated pediatrician-parent communication by content, analyzing medical encounters in a setting providing continuity of care. Thirty-eight encounters between middle class families and three senior pediatricians were audio-taped, transcribed, and analyzed for content. The categories of medical communica...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288202100507
更新日期:1982-05-01 00:00:00
abstract::The traditional American family has changed during the past several decades with increases in the number of single-parent households and working mothers. These changes have led to increased stress in the family when children become ill. Infectious diseases are the most common reasons parents seek care for ill children...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289703600403
更新日期:1997-04-01 00:00:00
abstract::Neisseria meningitidis is an important cause of fulminant septicemia and meningitis in children. Only limited reports of mild disease associated with this organism exist. In this study, we describe eight children, ages 2.5-19 months, with mild meningococcal disease and characterize the meningococcal isolates from some...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502401101
更新日期:1985-11-01 00:00:00
abstract::The objective was to determine the prevalence of therapies used by parents to manage acute diarrhea in their children and determine extent of parental adherence to current management guidelines and utilization of functional foods. Parents (N=623) of children with diarrhea were surveyed in a tertiary care pediatric eme...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808327057
更新日期:2009-04-01 00:00:00
abstract::Our primary objective was to compare parents of infants cared for in newborn intensive care units (NICUs) and infants cared for in well-baby ("general") nurseries with regard to knowledge and practice of safe sleep practices/sudden infant death syndrome risk reduction measures and guidelines. Our secondary objective w...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922813506038
更新日期:2013-11-01 00:00:00
abstract::This study was undertaken to evaluate trends and toxicity of pediatric methylphenidate exposures; 1993 to 1999 national poison center data were analyzed. There were 12,917 exposures, increasing from 927 in 1993 to 2,445 in 1999. The majority of children during the entire study period experienced no effect (60.3%) or m...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280304200210
更新日期:2003-03-01 00:00:00
abstract::The differential leukocyte count was studied within the first 24 hours of life in 115 infants of diabetic mothers (IDMs) appropriate for gestational age (AGA), 16 IDMs large for gestational age (LGA), 104 infants of non-diabetic mothers (INM's) AGA, and 22 INMs-LGA. A significant "shift to the left" was found in IDM's...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500806
更新日期:1986-08-01 00:00:00
abstract::Two hundred and seventy one infants were enrolled in a study to compare six different methods of treating the umbilical cord. Antimicrobial control was equal for all methods. Repeated triple dye application was considered least acceptable by staff and parents and had the longest attachment time. Povidone-iodine was as...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000992288802700302
更新日期:1988-03-01 00:00:00
abstract::Family health history (FHH) can identify families at increased risk for disease. Purpose. To learn mothers' (1) perceptions of the benefits of FHH and (2) willingness to complete a FHH tool, My Family Health Portrait (MFHP). Methods. Qualitative in-depth interviews were conducted with mothers recruited through Cincinn...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922812467531
更新日期:2013-01-01 00:00:00
abstract::An infant exposed in utero to valproic acid was born with multiple congenital malformations, including duodenal atresia, lumbar vertebral fusion, thoracolumbar scoliosis, renal abnormalities, diastasis recti abdominis, depigmentation of the eyebrows, and a large hemangioma. The child had neonatal hyperbilirubinemia an...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300611
更新日期:1984-06-01 00:00:00
abstract:BACKGROUND:This is a retrospective chart review of autistic patients presenting to the emergency department (ED) in a tertiary care pediatric center during the year 2011. RESULTS:There were 160 ED visits by 130 patients, 25% of visits were repeated, and 20% were admitted to the hospital. There were 126 (79%) male and ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814540983
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Control of environmental triggers (ETs) greatly improves asthma outcomes in children. Disseminating these findings to general pediatricians has not been well established. METHODS:After delivering a structured and standardized presentation on ET identification and control to pediatricians, we surveyed them a...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/0009922813482752
更新日期:2013-06-01 00:00:00
abstract::Lactobezoar is a compact mass of undigested milk concretions located within the gastrointestinal tract. Most often found in infants, they can precipitate gastric outlet obstruction, mimicking a variety of medical and surgical conditions. A common etiology and method of cure have yet to be elucidated. A review of the l...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280104001104
更新日期:2001-11-01 00:00:00
abstract::One pattern of dysfunctional family interaction is described as a syndrome. Four case histories are presented in which different family members take polar positions on various continua. In one instance the continuum is oral communication, with garrulousness on one side and silence on the other. Another continuum is fa...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288102000408
更新日期:1981-04-01 00:00:00
abstract::A study of 58 consecutive Indian infants operated for congenital hypertrophic pyloric stenosis revealed an accentuated male predominance in the incidence of the disease and far less preoperative hemetemesis as compared to that in their Western counterparts. 'Pyloric tumor' was palpable in 89% of cases. Only 34.5% of t...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002901002
更新日期:1990-10-01 00:00:00
abstract::Iron poisoning was a leading cause of pediatric morbidity and mortality. We sought to assess whether the removal of strict iron packaging requirements in 2003 resulted in an increase in iron-related morbidity and mortality in pediatric exposures. We performed a retrospective cohort study utilizing the National Poison ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922819901010
更新日期:2020-05-01 00:00:00
abstract::A comprehensive program was founded in 1982 to provide adolescents with prenatal and family planning care. The program's impact through its first five years of operation on medical aspects of pregnancy course and fetal outcome will be the subject of a separate report. This study examines subsequent maternal and infant...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289103000508
更新日期:1991-05-01 00:00:00
abstract::This study was done to evaluate the spectrum of diagnoses and identify risk factors for significant kidney disease in asymptomatic children with proteinuria and/or microhematuria detected by routine urinalysis. Clinical and laboratory data were obtained by retrospective chart review of 239 patients referred to a terti...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280504400105
更新日期:2005-01-01 00:00:00
abstract::Care coordination (CC) has shown positive outcomes among children with special health care needs (CSHCN); however, the association between CC and well-child care (WCC) visits is unknown. We hypothesize that CSHCN who receive CC are more likely to attend the recommended WCC visits. A retrospective cohort analysis was c...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820910823
更新日期:2020-06-01 00:00:00
abstract::More than 300 patients who presented consecutively to a sexual abuse clinic, a family planning clinic, and a family practice clinic filled out an anonymous survey regarding unwanted sexual experiences. In the family planning and family practice clinics, 40% of females and 16% of males reported having at least one unwa...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/000992289503400603
更新日期:1995-06-01 00:00:00