Abstract:
:A routine part of the process for developing National Institute for Health and Care Excellence (NICE) medical technologies guidance is a submission of clinical and economic evidence by the technology manufacturer. The Birmingham and Brunel Consortium External Assessment Centre (EAC; a consortium of the University of Birmingham and Brunel University) independently appraised the submission on the EXOGEN bone healing system for long bone fractures with non-union or delayed healing. This article is an overview of the original evidence submitted, the EAC's findings, and the final NICE guidance issued.
journal_name
Appl Health Econ Health Policyjournal_title
Applied health economics and health policyauthors
Higgins A,Glover M,Yang Y,Bayliss S,Meads C,Lord Jdoi
10.1007/s40258-014-0117-6subject
Has Abstractpub_date
2014-10-01 00:00:00pages
477-84issue
5eissn
1175-5652issn
1179-1896journal_volume
12pub_type
杂志文章,评审abstract::This paper reconsiders the evidence and several of the key arguments associated with the theory of supplier-induced demand (SID). It proposes a new theory to explain how ethical behaviour is consistent with SID. The purpose of a theory of demand and one criterion for the evaluation of a theory is the provision of a pl...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.2165/00148365-200605020-00003
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abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is the second most common cancer in Taiwan. For males in Taiwan, it is the most dangerous cancer, with both the highest incidence and mortality rate. OBJECTIVE:To determine cancer-related medical care costs for long-term survivors of HCC. METHODS:The estimation of the lifetim...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/00148365-200806010-00005
更新日期:2008-01-01 00:00:00
abstract::Central venous catheters are commonly used to deliver therapies and to monitor patients, and require securing at the point of percutaneous entry to avoid dislodgement. SecurAcath is a catheter securement device designed for central venous catheters. The National Institute for Health and Care Excellence, as a part of i...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-018-0427-1
更新日期:2018-12-01 00:00:00
abstract::Virtual Touch™ Quantification (VTq) is a software application used with Siemens Acuson ultrasound scanners to assess the stiffness of liver tissue. The National Institute for Health and Care Excellence (NICE) Medical Technologies Advisory Committee (MTAC) selected VTq for evaluation and invited the company to submit c...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-016-0277-7
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to construct an early economic evaluation for acalabrutinib for relapsed chronic lymphocytic leukaemia (CLL) to assist early reimbursement decision making. Scenarios were assessed to find the relative impact of critical parameters on incremental costs and quality-adjusted life...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-019-00496-1
更新日期:2019-12-01 00:00:00
abstract::The first objective of this paper is to expound the particular challenge posed by the occurrence of inconsistency in the expression of preferences by mental health patients to both economists and policy makers. Since this difficulty cannot be resolved, the second aim of the paper is to identify agents who may be count...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-019-00479-2
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:This research seeks to identify the relationship between economic factors related to the ability to receive and pay for health services and adverse cancer outcomes, as well as preventative screening and behavioral factors that influence the risk of cancer. We focus on the Northern High Plains region, where w...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-014-0099-4
更新日期:2014-08-01 00:00:00
abstract:CONTEXT:The in-hospital costs of extracorporeal membrane oxygenation (ECMO) have not been well established. OBJECTIVE:To evaluate the in-hospital costs of ECMO technology in both US and non-US settings for all patient types. DATA SOURCES:Systematic review of English-language articles, using the PubMed, Embase, Web of...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-015-0170-9
更新日期:2015-08-01 00:00:00
abstract::This paper examines the use of propensity score matching in economic analyses of observational data. Several excellent papers have previously reviewed practical aspects of propensity score estimation and other aspects of the propensity score literature. The purpose of this paper is to compare the conceptual foundation...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-013-0075-4
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:When pharmaceuticals are administered based on patient characteristics (for example weight or body surface area), an amount of product will be unused and must be disposed of. This wastage represents inefficiency and can distort decision making. METHODS:We present a method for the analysis of optimum fill vo...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-018-0444-0
更新日期:2019-06-01 00:00:00
abstract::We conducted a scoping review with the objective of synthesizing available literature and mapping what designs and methods have been used to evaluate health insurance reforms in sub-Saharan Africa. We systematically searched for scientific and grey literature in English and French published between 1980 and 2017 using...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-019-00499-y
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:The clinical management of intracranial aneurysms is debated in many countries because of the associated disability risk and costs. Therefore, estimating the costs and explaining their variability will provide important information for decision makers. OBJECTIVE:We aimed to evaluate the acute and post-acute...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-013-0041-1
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:In virologically suppressed patients, switching to darunavir/ritonavir (DRV/r) monotherapy maintains HIV RNA suppression, and could also lower treatment costs. OBJECTIVE:The purpose of this analysis was to calculate the potential cost savings from the use of DRV/r monotherapy in the UK. METHODS:In the MONE...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,随机对照试验
doi:10.2165/11592220-000000000-00000
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Price, income and health status are likely to affect the demand for healthcare in developing countries, and their quantitative effects are unclear in the literature. Some studies report that prices are not important determinants, while others conclude that prices are important determinants of the demand for ...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/BF03256160
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To develop a statistical model generating utility estimates for prostate cancer specific health states, using preference weights derived from the perspectives of prostate cancer patients, men at risk for prostate cancer, and society. METHODS:Utility estimate values were calculated using standard gamble (SG) ...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-016-0282-x
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:Invasive pneumococcal disease (IPD), pneumonia and acute otitis media (AOM) still represent a significant medical burden in children < 5 years of age in New Zealand (NZ), with marked disparities across socio-economic and ethnic groups. This cost-effectiveness evaluation aims to compare the potential impact o...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-018-0387-5
更新日期:2018-06-01 00:00:00
abstract::The biotech industry now accounts for a substantial and growing proportion of total R&D spending on new medicines. However, compared with the pharmaceutical industry, the biotech industry is financially fragile. This article illustrates the financial fragility of the biotech and pharmaceutical industries in the US and...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/BF03256149
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Opinions on the use of research abstracts in policy decision making are conflicting. We sought to evaluate the influence of research abstracts in guiding decisions of the Joint Oncology Drug Review of Canada (JODR), which conducts clinical and economic reviews of new cancer treatment drugs for ...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/11530510-000000000-00000
更新日期:2010-01-01 00:00:00
abstract::The rapid rise in pharmaceutical costs in France has been driven by new technologies and the growing prevalence of chronic diseases as well as considerable prescribing freedom and choice of physician among patients. This has led to the introduction of a number of reforms and initiatives in an attempt to moderate expen...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/BF03256162
更新日期:2010-01-01 00:00:00
abstract::Memokath-051 is a thermo-expandable, nickel-titanium alloy spiral stent used to treat ureteric obstruction resulting from malignant or benign strictures. The National Institute for Health and Care Excellence (NICE) selected Memokath-051 for evaluation. The company, PNN Medical, claimed Memokath-051 has clinical superi...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-018-0389-3
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Canadian patients, healthcare providers and payers share interest in assessing the value of self-monitoring of blood glucose (SMBG) for individuals with type 2 diabetes but not on insulin. Using the UKPDS (UK Prospective Diabetes Study) model, the Canadian Optimal Prescribing and Utilization Service (COMPUS)...
journal_title:Applied health economics and health policy
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doi:10.2165/11594270-000000000-00000
更新日期:2011-11-01 00:00:00
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journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:
更新日期:2003-01-01 00:00:00
abstract::The South Korean Government recently announced a reform in the drug anti-rebate law, with the purpose of eradicating pervasive, unethical, and illegal rebate practices in pharmaceutical marketing. The main objective of this reform is to have the ability to bring criminal charges against doctors and pharmacists for rec...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
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更新日期:2013-08-01 00:00:00
abstract::Economic models are developed to provide decision makers with information related to the real-world effectiveness of therapeutics, screening and diagnostic regimens. Although compliance with these regimens often has a significant impact on real-world clinical outcomes and costs, compliance and persistence have histori...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/BF03261872
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:The Xpert® MTB/RIF (Xpert) test has been shown to be effective and cost-effective for diagnosing tuberculosis (TB) under conditions with high HIV prevalence and HIV-TB co-infection but less is known about Xpert's cost in low HIV prevalence settings. Cambodia, a country with low HIV prevalence (0.7%), high TB...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-018-0397-3
更新日期:2018-08-01 00:00:00
abstract::Payment incentives to both consumers and providers have significant consequences for the equity and efficiency of a healthcare system, and have recently come to the fore in health policy reforms. This review first discusses the economic rationale for the apparent international convergence toward payment systems with m...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/00148365-200403010-00009
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Community-based health insurance (CBHI) schemes have been introduced in low- and middle-income countries to increase health service utilization and provide financial protection from high healthcare expenditures. OBJECTIVE:We assess the impact of household size on decisions to enroll in CBHI and demonstrate ...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-016-0222-9
更新日期:2016-04-01 00:00:00
abstract::The mandatory nature of recommendations made by the National Institute for Health and Clinical Excellence (NICE) in the UK has highlighted inherent difficulties in the process of disinvestment in existing technologies to fund NICE-approved technologies. A lack of evidence on candidate technologies means that the proce...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/BF03256137
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:There is obscurity regarding how US hospitals determine patients' charges. Whether insurance status influences a patient's hospital charge has not been explored. OBJECTIVE:The objective of this study was to determine whether hospitals charge patients differently based on their insurance status. METHODS:Thi...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-017-0308-z
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Osteoporosis is recognized as a serious health condition in developed as well as developing countries. There are no accurate estimates of the extent of the burden of osteoporosis in New Zealand. The purpose of this study was to estimate the economic burden of osteoporosis in New Zealand using data from inter...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/11531500-000000000-00000
更新日期:2011-03-01 00:00:00