Abstract：
AIM:To first compare the accuracy of self-, Physician-HPV testing and VIA as standalone screening tests; and second to compare the accuracy of Self-HPV positive test triaged with VIA with the different standalone screening tests as colposcopy and histologically confirmed CIN for cervical cancer screening in low-resource settings METHODS:1,601 women in Sharkya Governerate, Egypt concurrently received HPV DNA testing [Hybrid Capture 2 (HC2) assay] for self-collected and physician-obtained samples, and VIA. Women who tested positive for HPV DNA or VIA received colposcopy and biopsy. RESULTS:Percentage of women testing positive was 84.8 % on Self-HPV, 87.8 % on Physician-HPV, and 76.8 % on VIA. Test positivity increased in all screening methods with increasing severity of histopathologic diagnosis. Physician-HPV and HPV testing on a self-sample showed a very good agreement for HPV testing results [κ = 0.89 (95 % CI = 0.52-0.79)]; no statistically significant variation between age groups in the sensitivities of HPV testing on a self-sample, Physician-HPV testing for detecting CIN2 or CIN3 lesions. Conversely, VIA sensitivity was lower in detecting CIN2 and CIN3 than HPV testing on a self-sample and decreased significantly in the older age groups. HPV testing on a self-sample positive combined with VIA increases specificity to 98.1 % for CIN2 and 99.4 % for CIN3, and decreased colposcopy referral rate to 2.5 %. CONCLUSION:HPV testing on a self-sample is more accurate than VIA and as accurate as clinician-HPV testing for cervical cancer in low-resource settings.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Kamal EM,El Sayed GA,El Behery MM,El Shennawy GAdoi
10.1007/s00404-014-3321-6subject
Has Abstractpub_date
2014-12-01 00:00:00pages
1207-13issue
6eissn
0932-0067issn
1432-0711journal_volume
290pub_type
杂志文章abstract：OBJECTIVE:To identify differentially expressed genes (DEGs) in endometriosis and further analyze molecular mechanisms implicated in disease pathogenesis. MATERIALS AND METHODS:Gene expression data (ID: GSE7846) of human endometrial endothelial cells (HEECs) collected from eutopic endometria tissue of patients with and...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3875-y
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:The study aimed at determining the prevalence and associated risk factors for gestational diabetes mellitus (GDM) among antenatal women attending the Jos University Teaching Hospital (JUTH), Jos, Nigeria. METHODS:A cross-sectional study was done between February and April 2009 among 265 pregnant women enroll...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2649-z
更新日期：2013-05-01 00:00:00
abstract：:In this study, our aim was to compare the effects of metformin and gonadotropin releasing hormone (GnRH) analogues in clinical and hormonal parameters in women with polycystic ovary syndrome (PCOS). There were 50 women with PCOS who were included in our study and they were divided into two groups. In this randomized t...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00404-002-0344-1
更新日期：2003-06-01 00:00:00
abstract：PURPOSE:Serum anti-Mullerian hormone shows a strong positive correlation to the quantitative ovarian reserve but its correlation to embryo quality is unclear. This study assessed the association between serum AMH as a marker of ovarian reserve and embryo quality, using the technology of time-lapse imaging of the embryo...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4453-2
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:The management of ovarian cancer during pregnancy represents a major challenge and requires close multidisciplinary team approach. CASE:A 35-year-old pregnant woman with a yolk sac tumor underwent left salpingo-oophorectomy at 25 weeks of gestation. Chemotherapy was deferred to the end of the pregnancy owin...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-0977-4
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine whether the timing of prophylactic antibiotics at cesarean delivery influences maternal and neonatal infectious morbidity. STUDY DESIGN:This was a prospective, randomized trial. Four hundred patients that underwent elective cesarean section between June and December 200...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-008-0845-7
更新日期：2009-07-01 00:00:00
abstract：PURPOSE:Robotic surgery represents the latest development in the field of minimally invasive surgery and offers many technical advantages. Despite the higher costs, this novel approach has been applied increasingly in gynecological surgery. Regarding the implementation of a new operative method; however, the most impor...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05751-8
更新日期：2020-12-01 00:00:00
abstract：:Interleukin-6 (IL-6) is a pleiotropic cytokine that is not only a mediator in major immunologic reactions but also a growth factor of keratinocytes. We studied the IL-6 secretion in vitro of 15 human cell lines derived from both squamous cell carcinoma (SCC) and adenocarcinoma of the uterine cervix. Four of the eight ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF01370929
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:The aim of this study was to analyze whether the umbilical artery pH value can be estimated throughout CTG assessment 60 min prior to delivery and if the estimated umbilical artery pH value correlates with the actual one. This includes analysis of correlation between CTG trace classification and actual umbilica...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4516-4
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:The growing popularity and acceptance of integrative medicine is evident both among patients and among the oncologists treating them. As little data are available regarding health-care professionals' knowledge, attitudes, and practices relating to the topic, a nationwide online survey was designed. METHODS:Ove...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4420-y
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:To evaluate the possibility of using maternal anthropometric measurements for prediction of low birth weight in developing and developed countries. METHODS:Bivariate diagnostic meta-analysis was performed with hierarchical summary receiver operating characteristic curves. Ten databases, i.e., PubMed, EMBASE, C...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,meta分析
doi：10.1007/s00404-015-3721-2
更新日期：2015-10-01 00:00:00
abstract：:In the 72 h after a single oral dose of 400 mg of the antiprogesterone mifepristone, 12 out of 14 first and one second trimester fetuses had a slight increase in heart rate; 2 fetuses died and one aborted. During the same 72 h, uterine activity increased moderately, and was physiological with no increase in resting pr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00931376
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:Preterm birth (PTB) can be categorised according to aetiology into: spontaneous preterm labour (SPL), preterm prelabour rupture of membranes (PPROM), and iatrogenic (iatro) PTB. Outcomes could differ between these groups, which could be of interest in counselling. We aimed to explore differences between aetiolo...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05673-5
更新日期：2020-10-01 00:00:00
abstract：:Since 1985, after excluding nonimmunological reasons for habitual abortion, we have been performing an MCL, a cross-match, and an HLA typing in these patients. Those with a low MLC response and a negative cross-match are considered to be immunological aborters. Only three out of 42 examined couples showed a low respon...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF02417221
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:This study aimed to compare the clinical outcomes in different endometrial preparation methods prior to frozen embryo transfer (FET) in women with normal menstrual cycles. METHODS:A total of 471 eligible patients were randomly allocated into four groups of endometrial preparation prior to FET: natural cycle wi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-019-05062-7
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:The present meta-analysis aims to assess the efficacy of cervical cerclage retention after the occurrence of preterm premature rupture of the membranes by analyzing the observed maternal and neonatal perinatal outcomes. METHODS:We searched Medline (1966-2014), Scopus (2004-2014), Clinicaltrials.org (1997-2014)...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-014-3551-7
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:To investigate the function and mechanism of lnc NEAT1 in regulating the growth, migration and invasion of endometrial carcinoma (EC) cells. MATERIALS AND METHODS:NEAT1 and miR-214-3p levels were measured by qRT-PCR. The protein levels of HMGA1, β-catenin, c-myc and MMP9 were evaluated by Western blot. The e...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4365-1
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:The age-standardized incidence rate (ASR) of invasive cervical cancer in Israeli-Jewish women is persistently low compared to many other countries. The aim of the present study was to assess selected demographic characteristics of Israeli-Jewish women with cervical squamous cell carcinoma (SCC) in an attempt to...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1582-2
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy and safety of laparoscopic treatment of bladder endometriosis, especially in cases of full thickness endometriotic nodules. DESIGN:Retrospective review of medical records. SETTING:Tertiary medical center and a referral center for endometriosis. POPULATION:Sixty-nine patients with bla...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2917-6
更新日期：2013-12-01 00:00:00
abstract：:Traditional protocols for oxytocin infusion regimens recommend increases of infusion rate at 15-20 min intervals. However recent clinical studies agree that prolonged intervals of 30-40 or even 60 minutes are superior to shorter dosage intervals in terms of safety and efficacy. These results are in good agreement with...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00634710
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:To investigate the differences in steroid receptor expression patterns between glandular and stromal portions in endometrial polyps among premenopausal and postmenopausal patients and the relationship between the receptor expression in endometrial polyps and clinical parameters. MATERIALS AND METHODS:A total...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1142-9
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:In case of non-gynecological solid tumors and hematological malignancies diagnosed during pregnancy, individual diagnostic and treatment options must be established by an interdisciplinary team. METHODS:In part II of the present review we report on diagnostic and therapeutic principles in distinct entities of ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-011-2059-7
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:To assess the main neonatal morbidity results in relation to induced labour indications. METHODS:Historical groups from a total of 3,817 deliveries over a three year period (2009, 2010 and 2011) in "Mancha-Centro" Hospital (Alcázar de San Juan) formed the study group. All programmed and non-avoidable caesarean...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3349-7
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVE:To study the outcome of pregnancy in women with idiopathic thrombocytopenic purpura. MATERIALS AND METHODS:A retrospective analysis of 30 pregnancies in 26 women with idiopathic thrombocytopenic purpura was carried out at a tertiary hospital in India. The courses of the disease, maternal and perinatal outcom...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2958-x
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:Total laparoscopic hysterectomy (TLH) in the case of endometriosis may be extremely challenging. Our aim has been to analyze perioperative details and complications of TLH in women with vs. women without endometriosis. METHODS:Consecutive women who underwent TLH for endometriosis (endometriosis group) were com...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-016-4115-9
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:To evaluate women with delayed childbearing after 35 years and the perinatal profile of their surviving offspring in a low-income country. METHOD:A matched case-control study of advanced maternal age (AMA) parturients above 35 years was compared to younger mothers (20-35 years) in an inner-city maternity hos...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2105-5
更新日期：2012-04-01 00:00:00
abstract：:On the basis of 333 documented cases of permanent perinatal neurological damage, associated with arrest of the shoulders at birth, the authors conducted a retrospective study in order to evaluate the predisposing role, if any, of the utilization of extraction instruments. The investigation revealed that 35% of all inj...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-007-0465-7
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:Color Doppler ultrasound (CDU) accuracy of kidneys and bladder in the diagnosis and treatment of hydronephrosis and/or renal colic in pregnancies was evaluated. METHODS:Between January 2010 and September 2012, 234 pregnant women asymptomatic in 204 cases and with unilateral renal colic in 30 (median 26 years) ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2768-1
更新日期：2013-09-01 00:00:00
abstract：PURPOSE:The first part of the study involved data collection for the detection of geographic variations and chronologic fluctuations in the rates of shoulder dystocia. The second part of the research evaluated head-to-body delivery times in cases of arrest of the shoulders at birth that had resulted in fetal damage dur...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3453-8
更新日期：2015-04-01 00:00:00
abstract：:Female genital tuberculosis is a rare disease in developed countries but it is a frequent cause of chronic pelvic inflammatory disease and infertility in undeveloped countries. A rare case of tubercular endometritis diagnosed at hysteroscopy and successfully treated in a woman with secondary infertility, is presented....
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1325-4
更新日期：2010-06-01 00:00:00
