Sheep hemifacial and auricular transplantation models: an anatomic study.

Abstract:

INTRODUCTION:Currently, only a few large animal models, including swine, dog, and nonhuman primate, are described for composite face transplantation studies and the literature lacks reports on the large animal model of composite auricular transplantation. Large animal models offer better understanding of the immunological mechanisms and major histocompatibility complex characterization and, for this reason, are preferred to the small animal models for the assessment of new immunosuppressive tolerance induction protocols. Thus, the aim of this study was to demonstrate feasibility of dissection and exploration of vascular territories of the hemifacial and auricle transplantation models in the sheep cadavers. MATERIALS AND METHODS:Ten cadaver sheep heads were studied. The vascular territories of the composite hemifacial flap and composite auricle flap were defined by anatomical dissection. Methylene blue staining and laser-assisted indocyanine green angiography using SPY Elite System were used for vascular territories assessment. RESULTS:The dissection of cadaver sheep heads confirmed that the hemifacial flap and auricle flap can be raised on the same pedicle consisting of the common carotid artery and jugular vein. An adequate vascular network was observed in the flaps after injection of methylene blue dye via the arterial pedicle. Laser-assisted indocyanine green angiography identified vascular territories of the hemifacial and auricular vascular network. CONCLUSIONS:We described a new hemifacial and an auricular transplantation models in the sheep cadavers and have confirmed presence of the adequate vascular network as demonstrated by the laser-assisted angiography. This study introduces 2 new large animal models into the armamentarium of vascular composite allotransplantation.

journal_name

Ann Plast Surg

authors

Uygur S,Ozturk C,Kwiecien G,Djohan R,Siemionow M

doi

10.1097/SAP.0000000000000122

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

469-74

issue

4

eissn

0148-7043

issn

1536-3708

pii

00000637-201404000-00022

journal_volume

72

pub_type

杂志文章
  • Long-term survival in basal cell carcinoma metastatic to bone: a case report.

    abstract::A total of 97 cases of metastatic basal cell carcinoma have been reported in the literature, 22 of which were metastatic to bone. To date there has been no survival following bone metastasis. A case report of significant long-term survival--over three times the expected--is presented. The treatment described is perhap...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-197912000-00010

    authors: Briggs RM,Pestana I

    更新日期:1979-12-01 00:00:00

  • Effect of Cross-Sex Hormone Therapy on Venous Thromboembolism Risk in Male-to-Female Gender-Affirming Surgery.

    abstract::Individuals with gender dysphoria often seek medical interventions, such as hormone treatment and surgery, to live as their identified gender. Cross-sex hormone therapy typically consists of various estrogen formulations which confer varying risks of venous thromboembolism (VTE). Currently, there is no standard practi...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002300

    authors: Haveles CS,Wang MM,Arjun A,Zaila KE,Lee JC

    更新日期:2021-01-01 00:00:00

  • Aesthetic units in skin grafting of the face.

    abstract::In patients with difficult facial reconstructions, one of the most important requirements is to plan well, before beginning treatment. It is known that it is important to consider the aesthetic unit of the face. Each cutaneous area is to be reconstructed by a single, separate graft or flap. We present 4 patients illus...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199104000-00009

    authors: Maillard GF,Clavel PR

    更新日期:1991-04-01 00:00:00

  • Skeletal distraction of the hypoplastic mandible.

    abstract::Six patients underwent percutaneous pin placement, 17 intraoral corticotomies, and application of an Orthofix lengthening device to facilitate complex multiplanar distraction as mandated by the patient's specific deformity. The patients underwent gradual bony and soft-tissue distraction at the rate of .25 mm four time...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199502000-00004

    authors: Pensler JM,Goldberg DP,Lindell B,Carroll NC

    更新日期:1995-02-01 00:00:00

  • Building surgical capacity in low-resource countries: a qualitative analysis of task shifting from surgeon volunteers' perspectives.

    abstract:INTRODUCTION:Surgical volunteer organizations (SVOs) focus considerable resources on addressing the backlog of cases in low-resource countries. This model of service may perpetuate dependency. Efforts should focus on models that establish independence in providing surgical care. Independence could be achieved through s...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31826aefc7

    authors: Aliu O,Corlew SD,Heisler ME,Pannucci CJ,Chung KC

    更新日期:2014-01-01 00:00:00

  • Microvascular temporalis fascia transfer for penile girth enhancement.

    abstract::The authors report a 44-year-old man with inadequate penile girth that caused psychological problems. Using microvascular temporalis fascia transfer, they achieved satisfactory penile girth enhancement based on reliable vascularity in a single stage. ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200107000-00016

    authors: Küçükçelebi A,Ertaş NM,Aydin A,Eroğlu A,Ozmen E,Velidedeoğlu H

    更新日期:2001-07-01 00:00:00

  • Refining the intrinsic chimera flap: a review.

    abstract::Reconstruction of complex tissue deficiencies in which each missing component is in a different spatial relationship to each other can be particularly challenging, especially in patients with limited recipient vessels. The chimera flap design is uniquely suited to reconstruct these deformities. Chimera flaps have been...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章,评审

    doi:10.1097/SAP.0b013e318193499f

    authors: Agarwal JP,Agarwal S,Adler N,Gottlieb LJ

    更新日期:2009-10-01 00:00:00

  • Heel and foot reconstruction using reverse-flow posterior tibial flap.

    abstract::Island flaps supplied by the intermuscular cutaneous perforator (IMCP) from a deep vessel, such as the peroneal flap pedicled by IMCP from the peroneal vessel or the anterior tibial flap supplied by IMCP from the anterior tibial vessel, are reported to be useful in reconstructive procedures for soft-tissue defects of ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199004000-00004

    authors: Satoh K,Sakai M,Hiromatsu N,Ohsumi N

    更新日期:1990-04-01 00:00:00

  • Outpatient reduction mammaplasty: a review of 338 consecutive cases.

    abstract::Reduction mammaplasty is usually accomplished under general anesthesia, often with an overnight stay. With cost-containment pressures, the ability to perform this surgery in an outpatient setting would have obvious benefits. We present a series of 338 patients who have undergone bilateral reduction mammaplasty over a ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199602000-00010

    authors: Buenaventura S,Severinac R,Mullis W,Beasley M,Jacobs W,Wood D

    更新日期:1996-02-01 00:00:00

  • Explantation of 41-year-old implants following primary breast augmentation.

    abstract::The long-term affects of primary breast augmentation is a topic of controversy. This case report will highlight the long-term outcome in a woman with Ivalon sponge breast implants and the reasons for explantation. The focus of the manuscript will include mammography, capsular contracture, and late hematoma. ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000227520.00124.51

    authors: Nahabedian MY

    更新日期:2007-01-01 00:00:00

  • Current practice among plastic surgeons of antibiotic prophylaxis and closed-suction drains in breast reconstruction: experience, evidence, and implications for postoperative care.

    abstract:BACKGROUND:Despite their widespread use, there are no evidence-based guidelines on the management of closed-suction drains or antibiotics in postmastectomy breast reconstruction. The purpose of this study was to assess consensus and variation in postoperative care among plastic surgeons. METHODS:The authors designed a...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31820c0593

    authors: Phillips BT,Wang ED,Mirrer J,Lanier ST,Khan SU,Dagum AB,Bui DT

    更新日期:2011-05-01 00:00:00

  • Predicting the risk of reoperation in metopic synostosis: a quantitative CT scan analysis.

    abstract::Children with metopic synostosis have a well-described clinical picture of trigonocephaly, often with hypotelorbitism. The craniofacial disorder itself is well recognized; however, objective prognostic factors for predicting the risk of reoperation are not well known. In 39 children with metopic synostosis, measuremen...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.SAP.0000058498.64113.11

    authors: Paige KT,Cohen SR,Simms C,Burstein FD,Hudgins R,Boydston W

    更新日期:2003-08-01 00:00:00

  • Universal Applicability of the Furlow Palatoplasty: Resident as Primary Surgeon in a Consecutive, Nonselective Series.

    abstract:BACKGROUND:Questions persist regarding the general applicability of the Furlow palatoplasty technique, and thus, widespread adoption of its use has been uneven. This study describes a consecutive, nonselective series of primary Furlow palatoplasties. Highlighted is the unique fact that plastic surgical residents functi...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001261

    authors: Stotland MA,Boonipat T,Lundgren CM,Gonzalo EG

    更新日期:2018-04-01 00:00:00

  • Outcome and management of infected wounds after total hip arthroplasty.

    abstract::Infected wounds after total hip arthroplasty can be limb threatening. Management strategies are designed to eradicate infection, to obtain stable wound coverage, and to preserve the prosthesis. However, there is no general consensus for optimal management. The authors reviewed their 7-year combined orthopaedic and pla...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200212000-00006

    authors: Gusenoff JA,Hungerford DS,Orlando JC,Nahabedian MY

    更新日期:2002-12-01 00:00:00

  • Do histologic changes in the skin-lined neovagina of male-to-female transsexuals really occur?

    abstract::Controversy exists on whether or not the epidermal keratinizing squamous epithelium of skin grafts and flaps applied to line a neovagina changes histologically to a nonkeratinizing mucosal type squamous epithelium after vaginoplasty in male-to-female transsexuals. To end this discussion, the aim of this study was to o...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000258953.00234.50

    authors: Dekker JJ,Hage JJ,Karim RB,Bloemena E

    更新日期:2007-11-01 00:00:00

  • Subtotal midfacial/total nasal reconstruction following shotgun blast to the face employing composite microvascular serratus anterior rib, muscle, and scapular tip.

    abstract::A 40-year-old man presented with near-complete mid and lower facial destruction from a shotgun blast to the face. His midface was reconstructed with a serratus anterior muscle composite flap employing rib for nasal reconstruction and scapular tip for palate. Surfacing was done with split-thickness skin grafts. A tempo...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199703000-00018

    authors: Thomas WO,Harris CN

    更新日期:1997-03-01 00:00:00

  • The Chimera Flap: A Quarter Century Odyssey.

    abstract::Incredibly complicated multidimensional defects have always strained the ingenuity of the reconstructive surgeon. Secondary perhaps to vascularized composite allotransplantation as a solution to this dilemma, the compound flap has been developed to be a more useful and available alternative. Their greatest versatility...

    journal_title:Annals of plastic surgery

    pub_type: 历史文章,杂志文章

    doi:10.1097/SAP.0000000000000884

    authors: Hallock GG

    更新日期:2017-02-01 00:00:00

  • A comparison between proximal lateral leg flap and radial forearm flap for intraoral reconstruction.

    abstract::Free flaps have become a popular option for the reconstruction of intraoral defects. The radial forearm flap used to be the workhorse flap for small and thin defects, but was associated with numerous donor-site morbidities. The proximal lateral leg flap can provide a thin and pliable tissue similar to the radial forea...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000000047

    authors: Lee JT,Chen PR,Cheng LF,Wang CH,Wu MS,Huang CC,Chien SH,Hsu H

    更新日期:2013-12-01 00:00:00

  • Unilateral Cleft Lip Repair: A Quantitative Scale Assessment of Postoperative Lip and Nose Scars Across 2 Operative Techniques.

    abstract:BACKGROUND:There is no quantitative evidence supporting one unilateral cleft lip (UCL) repair technique over the other with regard to scarring. We sought to evaluate the difference between the extended Mohler and Millard techniques, using 3 scar assessment scales. METHODS:Postoperative frontal and basal photographs of...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001991

    authors: Ramly EP,Eisemann BS,Kantar RS,Alfonso AR,Wang M,Diaz-Siso JR,Staffenberg DA,Flores RL

    更新日期:2019-12-01 00:00:00

  • External fixation of extremity flaps and grafts.

    abstract::Positioning extremities after soft-tissue reconstructive procedures can be difficult, particularly when flaps or skin grafts have been placed for posterior or circumferential defects. We describe a method using the patient's existing external fixator, when present, to aid in the postoperative care and positioning of t...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199102000-00017

    authors: Bindiger A,Ecker J,Kuschner S,Sherman R

    更新日期:1991-02-01 00:00:00

  • Chest wall reconstruction in a pediatric patient with ectopia cordis.

    abstract::Ectopia cordis is defined as a congenital malposition of the heart outside of the thoracic cavity. It is a rare condition, and complete ectopia cordis can be a fatal condition. Successful surgical reconstruction of this defect has been reported but is uncommon. The general approach to reconstructing the chest wall inv...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3181c5a7ff

    authors: Mohan R,Peralta M,Perez R,Rosenkranz ER,Panthaki ZJ

    更新日期:2010-08-01 00:00:00

  • Microsurgical ear replantation without venous repair: failure of development of venous channels despite patency of arterial anastomosis for 14 days.

    abstract::The authors describe a case of microvascular ear replantation with repair of the artery only and medicinal leech therapy that survived for 14 days but ultimately failed as a result of the absence of development of venous channels between the replant and the recipient bed. A 35-year-old man presented with complete avul...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200104000-00016

    authors: Akyürek M,Safak T,Keçik A

    更新日期:2001-04-01 00:00:00

  • Intraosseous ganglion of the lunate.

    abstract::Intraosseous ganglia are occasionally found affecting the carpal bones of the hand and should be considered in the differential diagnosis of chronic wrist pain. They have characteristic radiographic findings of a cyst with a thin sclerotic rim. This case report illustrates an unusual presentation of a cyst in the luna...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200204000-00018

    authors: Bennett DC,Hauck RM

    更新日期:2002-04-01 00:00:00

  • The free dorsoradial forearm perforator flap: anatomical study and clinical application in finger reconstruction.

    abstract::The perforator flaps are characterized by their thinness and the adjustable length of their vascular pedicle. The purpose of this investigation is to refine the anatomy of the perforators in the middorsoradial forearm and present our clinical experience using this free perforator flap in the reconstruction of finger d...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3181d3772e

    authors: Gao W,Yan H,Li Z,Li X,Jiang L,Yu Q,Maxwell EH,Zhang F

    更新日期:2011-01-01 00:00:00

  • Investigation of Prognostic Features in Primary Cutaneous and Soft Tissue Angiosarcoma After Surgical Resection: A Retrospective Study.

    abstract::Primary cutaneous and soft tissue angiosarcoma is a rare but highly aggressive malignancy. To date, surgical resection is the mainstay of treatment, but poor prognosis is expected. To investigate whether there are factors associated with poor prognosis after surgical resection and to develop a treatment guideline for ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001004

    authors: Lee BL,Chen CF,Chen PC,Lee HC,Liao WC,Perng CK,Ma H,Lin CH

    更新日期:2017-03-01 00:00:00

  • Automated facial image analysis: detecting improvement in abnormal facial movement after treatment with botulinum toxin A.

    abstract::The purpose of this study was to evaluate the ability of Automated Facial Image Analysis (AFA) to detect changes in facial motion after Botox injections in patients with facial nerve disorders accompanied by abnormal muscle activity. Eight subjects received Botox for oral to ocular synkinesis (n = 6), ocular to oral s...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000250761.26824.4f

    authors: Rogers CR,Schmidt KL,VanSwearingen JM,Cohn JF,Wachtman GS,Manders EK,Deleyiannis FW

    更新日期:2007-01-01 00:00:00

  • The effect of saliva and oral intake on the tensile properties of sutures: an experimental study.

    abstract::The plastic surgeon often operates in the oral cavity. Little or no information exists regarding the effect of saliva and oral intake upon the tensile properties of suture. Polyglactin 910 (Vicryl) and chromic gut were studied. Five sutures of each type were subjected to saline, saliva, milk, or soy milk over differen...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000245071.98517.8c

    authors: Ferguson RE Jr,Schuler K,Thornton BP,Vasconez HC,Rinker B

    更新日期:2007-03-01 00:00:00

  • The superior dermoglandular pedicle approach to breast reduction.

    abstract::The superior dermoglandular pedicle technique of breast reduction and its results in 193 reductions are presented. This technique offers aesthetically pleasing results, sensate nipple/areola complex, and safety. The natural shape obtained results from preservation of the superior portion of the breast tissue (where ti...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199209000-00004

    authors: Robbins LB,Hoffman DK

    更新日期:1992-09-01 00:00:00

  • Management of tattoos in the operative field.

    abstract::Tattooing is increasingly common in Western society. The aim of the study was to create an overview of the surgical options when a tattoo is present in the operative site and to present an algorithm for the surgical plan.A literature-based study was conducted, using the Pubmed database. The following search terms have...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章,评审

    doi:10.1097/SAP.0b013e3181b1429f

    authors: Smit JM,Scheele K,Lapid O,Hoogbergen MM

    更新日期:2010-01-01 00:00:00

  • Reconstruction of defects after excision of facial skin cancer using a venous free flap.

    abstract::After extensive excision of skin cancer on the face, or when skin cancer is located on the 3-dimensional structures of the face, reconstruction with a local flap can be impossible, or clinicians are reluctant to reconstruct defects with a skin graft because of postoperative contraction, hyperpigmentation, or other com...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e318209a77f

    authors: Park SW,Heo EP,Choi JH,Cho HC,Kim SH,Xu L,Lee Y,Choi TH,Kim S

    更新日期:2011-12-01 00:00:00